Activation of NF-κB in Schwann cells is dispensable for myelination In vivo

Paul D. Morton, Anna Dellarole, Michelle H. Theus, Winston M. Walters, Summer S. Berge, John R. Bethea

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Peripheral myelination is a dynamic process orchestrated by axons and Schwann cells. Although the signaling mechanisms governing myelination are not fully understood, NF-κB activation in Schwann cells has been implicated as a key regulator in vitro. Using a mouse model, we show that nuclear factor κB activation in Schwann cells is not required for myelination in vivo.

Original languageEnglish
Pages (from-to)9932-9936
Number of pages5
JournalJournal of Neuroscience
Volume33
Issue number24
DOIs
StatePublished - Jun 17 2013

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Schwann Cells
Axons

ASJC Scopus subject areas

  • Neuroscience(all)

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Morton, P. D., Dellarole, A., Theus, M. H., Walters, W. M., Berge, S. S., & Bethea, J. R. (2013). Activation of NF-κB in Schwann cells is dispensable for myelination In vivo. Journal of Neuroscience, 33(24), 9932-9936. https://doi.org/10.1523/JNEUROSCI.2483-12.2013

Activation of NF-κB in Schwann cells is dispensable for myelination In vivo. / Morton, Paul D.; Dellarole, Anna; Theus, Michelle H.; Walters, Winston M.; Berge, Summer S.; Bethea, John R.

In: Journal of Neuroscience, Vol. 33, No. 24, 17.06.2013, p. 9932-9936.

Research output: Contribution to journalArticle

Morton, PD, Dellarole, A, Theus, MH, Walters, WM, Berge, SS & Bethea, JR 2013, 'Activation of NF-κB in Schwann cells is dispensable for myelination In vivo', Journal of Neuroscience, vol. 33, no. 24, pp. 9932-9936. https://doi.org/10.1523/JNEUROSCI.2483-12.2013
Morton PD, Dellarole A, Theus MH, Walters WM, Berge SS, Bethea JR. Activation of NF-κB in Schwann cells is dispensable for myelination In vivo. Journal of Neuroscience. 2013 Jun 17;33(24):9932-9936. https://doi.org/10.1523/JNEUROSCI.2483-12.2013
Morton, Paul D. ; Dellarole, Anna ; Theus, Michelle H. ; Walters, Winston M. ; Berge, Summer S. ; Bethea, John R. / Activation of NF-κB in Schwann cells is dispensable for myelination In vivo. In: Journal of Neuroscience. 2013 ; Vol. 33, No. 24. pp. 9932-9936.
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