Acquired progressive kinking of the hair. Clinical features, pathological study, and follow-up of 7 patients

Antonella Tosti, Bianca Maria Piraccini, Massimiliano Pazzaglia, Cosimo Misciali

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Background: Acquired progressive kinking of the hair (APKH) is a relatively rare condition, with fewer than 20 cases reported in the literature. Whether APKH is a separate entity or a variety of androgenetic alopecia is still controversial. This study reviews the clinical and pathological features and long-term follow-up of 7 patients with APKH. Observations: Since January 1989, we have diagnosed APKH in 7 males aged 15 to 22 years. All patients had strong family history for androgenetic alopecia. Hair kinking affected the frontotemporal region and/or the vertex where the hair appeared curly, frizzy, and lusterless. The pathological features of the affected scalp were consistent with the diagnosis of the early stages of androgenetic alopecia. In all patients, APKH evolved into androgenetic alopecia during the follow-up period. Mean follow-up was 4.5 years (range, 2-9 years). Treatment with topical minoxidil did not prevent development of hair-thinning in the scalp areas affected by hair kinking. Conclusions: The term acquired progressive kinking of the hair encompasses a number of conditions characterized by acquired curling of the scalp hair. Acquired hair kinking on the androgen-dependent areas of the scalp represents a modality of onset of androgenetic alopecia associated with poor prognosis.

Original languageEnglish
Pages (from-to)1223-1226
Number of pages4
JournalArchives of Dermatology
Volume135
Issue number10
DOIs
StatePublished - Oct 1 1999
Externally publishedYes

Fingerprint

Hair
Alopecia
Scalp
Minoxidil
Androgens

ASJC Scopus subject areas

  • Dermatology

Cite this

Acquired progressive kinking of the hair. Clinical features, pathological study, and follow-up of 7 patients. / Tosti, Antonella; Piraccini, Bianca Maria; Pazzaglia, Massimiliano; Misciali, Cosimo.

In: Archives of Dermatology, Vol. 135, No. 10, 01.10.1999, p. 1223-1226.

Research output: Contribution to journalArticle

Tosti, Antonella ; Piraccini, Bianca Maria ; Pazzaglia, Massimiliano ; Misciali, Cosimo. / Acquired progressive kinking of the hair. Clinical features, pathological study, and follow-up of 7 patients. In: Archives of Dermatology. 1999 ; Vol. 135, No. 10. pp. 1223-1226.
@article{e830f548e7024daab02b6cbb8dc24f0b,
title = "Acquired progressive kinking of the hair. Clinical features, pathological study, and follow-up of 7 patients",
abstract = "Background: Acquired progressive kinking of the hair (APKH) is a relatively rare condition, with fewer than 20 cases reported in the literature. Whether APKH is a separate entity or a variety of androgenetic alopecia is still controversial. This study reviews the clinical and pathological features and long-term follow-up of 7 patients with APKH. Observations: Since January 1989, we have diagnosed APKH in 7 males aged 15 to 22 years. All patients had strong family history for androgenetic alopecia. Hair kinking affected the frontotemporal region and/or the vertex where the hair appeared curly, frizzy, and lusterless. The pathological features of the affected scalp were consistent with the diagnosis of the early stages of androgenetic alopecia. In all patients, APKH evolved into androgenetic alopecia during the follow-up period. Mean follow-up was 4.5 years (range, 2-9 years). Treatment with topical minoxidil did not prevent development of hair-thinning in the scalp areas affected by hair kinking. Conclusions: The term acquired progressive kinking of the hair encompasses a number of conditions characterized by acquired curling of the scalp hair. Acquired hair kinking on the androgen-dependent areas of the scalp represents a modality of onset of androgenetic alopecia associated with poor prognosis.",
author = "Antonella Tosti and Piraccini, {Bianca Maria} and Massimiliano Pazzaglia and Cosimo Misciali",
year = "1999",
month = "10",
day = "1",
doi = "10.1001/archderm.135.10.1223",
language = "English",
volume = "135",
pages = "1223--1226",
journal = "JAMA Dermatology",
issn = "2168-6068",
publisher = "American Medical Association",
number = "10",

}

TY - JOUR

T1 - Acquired progressive kinking of the hair. Clinical features, pathological study, and follow-up of 7 patients

AU - Tosti, Antonella

AU - Piraccini, Bianca Maria

AU - Pazzaglia, Massimiliano

AU - Misciali, Cosimo

PY - 1999/10/1

Y1 - 1999/10/1

N2 - Background: Acquired progressive kinking of the hair (APKH) is a relatively rare condition, with fewer than 20 cases reported in the literature. Whether APKH is a separate entity or a variety of androgenetic alopecia is still controversial. This study reviews the clinical and pathological features and long-term follow-up of 7 patients with APKH. Observations: Since January 1989, we have diagnosed APKH in 7 males aged 15 to 22 years. All patients had strong family history for androgenetic alopecia. Hair kinking affected the frontotemporal region and/or the vertex where the hair appeared curly, frizzy, and lusterless. The pathological features of the affected scalp were consistent with the diagnosis of the early stages of androgenetic alopecia. In all patients, APKH evolved into androgenetic alopecia during the follow-up period. Mean follow-up was 4.5 years (range, 2-9 years). Treatment with topical minoxidil did not prevent development of hair-thinning in the scalp areas affected by hair kinking. Conclusions: The term acquired progressive kinking of the hair encompasses a number of conditions characterized by acquired curling of the scalp hair. Acquired hair kinking on the androgen-dependent areas of the scalp represents a modality of onset of androgenetic alopecia associated with poor prognosis.

AB - Background: Acquired progressive kinking of the hair (APKH) is a relatively rare condition, with fewer than 20 cases reported in the literature. Whether APKH is a separate entity or a variety of androgenetic alopecia is still controversial. This study reviews the clinical and pathological features and long-term follow-up of 7 patients with APKH. Observations: Since January 1989, we have diagnosed APKH in 7 males aged 15 to 22 years. All patients had strong family history for androgenetic alopecia. Hair kinking affected the frontotemporal region and/or the vertex where the hair appeared curly, frizzy, and lusterless. The pathological features of the affected scalp were consistent with the diagnosis of the early stages of androgenetic alopecia. In all patients, APKH evolved into androgenetic alopecia during the follow-up period. Mean follow-up was 4.5 years (range, 2-9 years). Treatment with topical minoxidil did not prevent development of hair-thinning in the scalp areas affected by hair kinking. Conclusions: The term acquired progressive kinking of the hair encompasses a number of conditions characterized by acquired curling of the scalp hair. Acquired hair kinking on the androgen-dependent areas of the scalp represents a modality of onset of androgenetic alopecia associated with poor prognosis.

UR - http://www.scopus.com/inward/record.url?scp=0032696234&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032696234&partnerID=8YFLogxK

U2 - 10.1001/archderm.135.10.1223

DO - 10.1001/archderm.135.10.1223

M3 - Article

C2 - 10522670

AN - SCOPUS:0032696234

VL - 135

SP - 1223

EP - 1226

JO - JAMA Dermatology

JF - JAMA Dermatology

SN - 2168-6068

IS - 10

ER -