Acquired peripapillary changes and progression in glaucoma

Edward J. Rockwood, Douglas Anderson

Research output: Contribution to journalArticle

66 Citations (Scopus)

Abstract

In a review of fundus photographs, changes in the degree of depigmentation or atrophy of the retinal pigment epithelium (RPE) were observed near the disc over time in 21% of cases with progressive glaucomatous cupping, but they also occurred as a natural phenomenon over time in 4% of eyes with nonprogressive glaucoma and in 3% of nonglaucomatous eyes. Thus, the peripapillary RPE shows some progressive alteration in normal individuals, but also may sometimes suffer along with the axons during glaucomatous damage. The acquired changes observed in the progressive glaucomatous eyes seem too small and too infrequent to account for the high prevalence of large haloes and crescents seen around the optic disc in glaucoma.

Original languageEnglish
Pages (from-to)510-515
Number of pages6
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Volume226
Issue number6
DOIs
StatePublished - Nov 1 1988

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Glaucoma
Retinal Pigment Epithelium
Optic Disk
Atrophy
Axons

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Acquired peripapillary changes and progression in glaucoma. / Rockwood, Edward J.; Anderson, Douglas.

In: Graefe's Archive for Clinical and Experimental Ophthalmology, Vol. 226, No. 6, 01.11.1988, p. 510-515.

Research output: Contribution to journalArticle

Rockwood, Edward J. ; Anderson, Douglas. / Acquired peripapillary changes and progression in glaucoma. In: Graefe's Archive for Clinical and Experimental Ophthalmology. 1988 ; Vol. 226, No. 6. pp. 510-515.
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