Acquired Immune Deficiency Syndrome in Low-Risk Patients: Evidence for Possible Transmission by an Asymptomatic Carrier

Arthur E. Pitchenik, Margaret A. Fischl, Thomas J. Spira

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

Two patients who contracted acquired immune deficiency syndrome (AIDS) could not be included in any of the known high-risk groups for this syndrome (i.e., they were not homosexual, intravenous [IV] drug abusers, Haitian, or hemophiliacs). Patient 1, however, had regular sexual contact with her husband, an IV drug abuser who is asymptomatic despite a severe T-cell defect (T-helper cells, 33/cu mm; T-helper/T-suppressor ratio, 0.32; and a depressed lymphoproliferative response to mitogens and antigens). We hypothesize that he may be an asymptomatic carrier of an AIDS agent that he transmitted to his wife through intimate heterosexual contact. This mode of sexual transmission may provide a vector for the spread of AIDS to low-risk populations.

Original languageEnglish (US)
Pages (from-to)1310-1312
Number of pages3
JournalJAMA: The Journal of the American Medical Association
Volume250
Issue number10
DOIs
StatePublished - Sep 9 1983

ASJC Scopus subject areas

  • Medicine(all)

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