Abstract
Two patients who contracted acquired immune deficiency syndrome (AIDS) could not be included in any of the known high-risk groups for this syndrome (i.e., they were not homosexual, intravenous [IV] drug abusers, Haitian, or hemophiliacs). Patient 1, however, had regular sexual contact with her husband, an IV drug abuser who is asymptomatic despite a severe T-cell defect (T-helper cells, 33/cu mm; T-helper/T-suppressor ratio, 0.32; and a depressed lymphoproliferative response to mitogens and antigens). We hypothesize that he may be an asymptomatic carrier of an AIDS agent that he transmitted to his wife through intimate heterosexual contact. This mode of sexual transmission may provide a vector for the spread of AIDS to low-risk populations.
| Original language | English |
|---|---|
| Pages (from-to) | 1310-1312 |
| Number of pages | 3 |
| Journal | Journal of the American Medical Association |
| Volume | 250 |
| Issue number | 10 |
| DOIs | |
| State | Published - Jan 1 1983 |
Fingerprint
ASJC Scopus subject areas
- Medicine(all)
Cite this
Acquired immune deficiency syndrome in low-risk patients. Evidence for possible transmission by an asymptomatic carrier. / Pitchenik, A. E.; Fischl, Margaret A; Spira, T. J.
In: Journal of the American Medical Association, Vol. 250, No. 10, 01.01.1983, p. 1310-1312.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Acquired immune deficiency syndrome in low-risk patients. Evidence for possible transmission by an asymptomatic carrier
AU - Pitchenik, A. E.
AU - Fischl, Margaret A
AU - Spira, T. J.
PY - 1983/1/1
Y1 - 1983/1/1
N2 - Two patients who contracted acquired immune deficiency syndrome (AIDS) could not be included in any of the known high-risk groups for this syndrome (i.e., they were not homosexual, intravenous [IV] drug abusers, Haitian, or hemophiliacs). Patient 1, however, had regular sexual contact with her husband, an IV drug abuser who is asymptomatic despite a severe T-cell defect (T-helper cells, 33/cu mm; T-helper/T-suppressor ratio, 0.32; and a depressed lymphoproliferative response to mitogens and antigens). We hypothesize that he may be an asymptomatic carrier of an AIDS agent that he transmitted to his wife through intimate heterosexual contact. This mode of sexual transmission may provide a vector for the spread of AIDS to low-risk populations.
AB - Two patients who contracted acquired immune deficiency syndrome (AIDS) could not be included in any of the known high-risk groups for this syndrome (i.e., they were not homosexual, intravenous [IV] drug abusers, Haitian, or hemophiliacs). Patient 1, however, had regular sexual contact with her husband, an IV drug abuser who is asymptomatic despite a severe T-cell defect (T-helper cells, 33/cu mm; T-helper/T-suppressor ratio, 0.32; and a depressed lymphoproliferative response to mitogens and antigens). We hypothesize that he may be an asymptomatic carrier of an AIDS agent that he transmitted to his wife through intimate heterosexual contact. This mode of sexual transmission may provide a vector for the spread of AIDS to low-risk populations.
UR - http://www.scopus.com/inward/record.url?scp=0020604460&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0020604460&partnerID=8YFLogxK
U2 - 10.1001/jama.250.10.1310
DO - 10.1001/jama.250.10.1310
M3 - Article
C2 - 6224028
AN - SCOPUS:0020604460
VL - 250
SP - 1310
EP - 1312
JO - JAMA - Journal of the American Medical Association
JF - JAMA - Journal of the American Medical Association
SN - 0002-9955
IS - 10
ER -