Acid-base physiology and CO2 homeostasis: Regulation and compensation in response to elevated environmental CO2

Colin J. Brauner, Ryan B. Shartau, Christian Damsgaard, Andrew J. Esbaugh, Rod W. Wilson, Martin Grosell

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Citations (Scopus)

Abstract

Acid-base balance is one of the most tightly regulated physiological processes. Accumulation of metabolic CO2 produced at the tissues causes extra- or intracellular acidosis that can disrupt cellular processes. Consequently, fish have a well-developed system for CO2 transport and excretion; however, the system varies significantly among fish groups, which we review in this chapter. Elevated environmental CO2 that occurs naturally or due to anthropogenic factors (e.g., climate change and in aquaculture), in both freshwater and seawater, induces a rapid acid-base disturbance in fish. The resulting acidosis is compensated by a net elevation in plasma HCO3 in exchange for [Cl], primarily through processes at the gills, but also the kidney. The rate and completeness of acid-base compensation during CO2 exposure is affected by water ion composition, and at high CO2 levels, there appears to be an upper limit to the increase in plasma HCO3 . Fish that naturally live in such high CO2 environments appear to have an exceptional capacity for intracellular pH regulation. While it has long been thought that fish would not be affected by climate change relevant CO2 levels, negative physiological effects are seen. The effect of fluctuating CO2 levels in both marine and freshwater environments may be especially problematic, and an area where more research is required.

Original languageEnglish (US)
Title of host publicationFish Physiology
EditorsMartin Grosell, Philip L. Munday, Anthony P. Farrell, Colin J. Brauner
PublisherElsevier Inc.
Pages69-132
Number of pages64
ISBN (Print)9780128176092
DOIs
StatePublished - 2019

Publication series

NameFish Physiology
Volume37
ISSN (Print)1546-5098

Fingerprint

homeostasis
Fishes
Homeostasis
physiology
Acids
acids
fish
Climate Change
acidosis
Acidosis
Fresh Water
climate change
freshwater aquaculture
Physiological Phenomena
Aquaculture
acid-base balance
Acid-Base Equilibrium
Seawater
gills
excretion

Keywords

  • Acid-base regulation
  • Aquaculture
  • Carbon dioxide
  • Climate change
  • Fish
  • Freshwater acidification
  • Ocean acidification
  • Preferential pH regulation

ASJC Scopus subject areas

  • Physiology
  • Animal Science and Zoology

Cite this

Brauner, C. J., Shartau, R. B., Damsgaard, C., Esbaugh, A. J., Wilson, R. W., & Grosell, M. (2019). Acid-base physiology and CO2 homeostasis: Regulation and compensation in response to elevated environmental CO2. In M. Grosell, P. L. Munday, A. P. Farrell, & C. J. Brauner (Eds.), Fish Physiology (pp. 69-132). (Fish Physiology; Vol. 37). Elsevier Inc.. https://doi.org/10.1016/bs.fp.2019.08.003

Acid-base physiology and CO2 homeostasis : Regulation and compensation in response to elevated environmental CO2. / Brauner, Colin J.; Shartau, Ryan B.; Damsgaard, Christian; Esbaugh, Andrew J.; Wilson, Rod W.; Grosell, Martin.

Fish Physiology. ed. / Martin Grosell; Philip L. Munday; Anthony P. Farrell; Colin J. Brauner. Elsevier Inc., 2019. p. 69-132 (Fish Physiology; Vol. 37).

Research output: Chapter in Book/Report/Conference proceedingChapter

Brauner, CJ, Shartau, RB, Damsgaard, C, Esbaugh, AJ, Wilson, RW & Grosell, M 2019, Acid-base physiology and CO2 homeostasis: Regulation and compensation in response to elevated environmental CO2. in M Grosell, PL Munday, AP Farrell & CJ Brauner (eds), Fish Physiology. Fish Physiology, vol. 37, Elsevier Inc., pp. 69-132. https://doi.org/10.1016/bs.fp.2019.08.003
Brauner CJ, Shartau RB, Damsgaard C, Esbaugh AJ, Wilson RW, Grosell M. Acid-base physiology and CO2 homeostasis: Regulation and compensation in response to elevated environmental CO2. In Grosell M, Munday PL, Farrell AP, Brauner CJ, editors, Fish Physiology. Elsevier Inc. 2019. p. 69-132. (Fish Physiology). https://doi.org/10.1016/bs.fp.2019.08.003
Brauner, Colin J. ; Shartau, Ryan B. ; Damsgaard, Christian ; Esbaugh, Andrew J. ; Wilson, Rod W. ; Grosell, Martin. / Acid-base physiology and CO2 homeostasis : Regulation and compensation in response to elevated environmental CO2. Fish Physiology. editor / Martin Grosell ; Philip L. Munday ; Anthony P. Farrell ; Colin J. Brauner. Elsevier Inc., 2019. pp. 69-132 (Fish Physiology).
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