Accelerating discovery with on-demand LIMS

Research output: Contribution to journalArticle

Abstract

Researchers at LemBix Laboratory, a part of the Miami Project to Cure Paralysis, conducts high-content screening (HCS) of neurons aimed at finding new or improved treatments for spinal cord injury and other neurological disorders. HCS offers an ideal way to identify genes, molecular pathways and, ultimately, drugs that can promote the regeneration of central nervous system nerve cells. The team at the laboratory focuses on understanding how nerve cells extend their long processes, called axons, to their targets, why young neurons do it so successfully and why older neurons have lost their ability to do this. The team selected Thermo Scientific Nautilus to meet its research needs, due to its ease of developing workflows and sophisticated plate handling. The team use complicated media and many different types of reagents for cell culture and screening. The team also installed enterprise-level laboratory information management systems (LIMS) in 2008, using an Oracle database on the central University servers.

Original languageEnglish
Pages (from-to)25-27
Number of pages3
JournalScientific Computing
Volume27
Issue number6
StatePublished - Nov 1 2010

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Clinical Laboratory Information Systems
management information systems
Information Management
Information management
Neurons
neurons
screening
nerves
Screening
spinal cord injuries
paralysis
Nautilus
axons
central nervous system
cells
regeneration
genes
Workflow
reagents
Neurology

ASJC Scopus subject areas

  • Computer Science(all)

Cite this

Accelerating discovery with on-demand LIMS. / Lemmon, Vance.

In: Scientific Computing, Vol. 27, No. 6, 01.11.2010, p. 25-27.

Research output: Contribution to journalArticle

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