Absence of hippocampal sclerosis in children with multiple daily seizures since infancy

Sanjeev V. Kothare; Ana Sotrel; Michael Duchowny; Prasanna Jayakar; Paul C. Marshall; Thomas W. Smith

doi:10.1177/088307380101600804

Absence of hippocampal sclerosis in children with multiple daily seizures since infancy

Sanjeev V. Kothare, Ana Sotrel, Michael Duchowny, Prasanna Jayakar, Paul C. Marshall, Thomas W. Smith

Neurology

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

We report a series of nine children with multiple daily seizures since infancy who underwent functional hemispherectomy that included en bloc resection of the hippocampus and the temporal neocortex. In all cases, the hippocampi were normal by conventional histology despite the fact that these patients had suffered from recurrent seizures over a long period of time. This observation suggests that extremely frequent seizures in childhood are not invariably associated with the development of hippocampal sclerosis.

Original language	English (US)
Pages (from-to)	562-564
Number of pages	3
Journal	Journal of child neurology
Volume	16
Issue number	8
DOIs	https://doi.org/10.1177/088307380101600804
State	Published - Jan 1 2001

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Clinical Neurology

Access to Document

10.1177/088307380101600804

Cite this

@article{aee8cdfc3fd2449ca750b95c8e7c53ef,

title = "Absence of hippocampal sclerosis in children with multiple daily seizures since infancy",

abstract = "We report a series of nine children with multiple daily seizures since infancy who underwent functional hemispherectomy that included en bloc resection of the hippocampus and the temporal neocortex. In all cases, the hippocampi were normal by conventional histology despite the fact that these patients had suffered from recurrent seizures over a long period of time. This observation suggests that extremely frequent seizures in childhood are not invariably associated with the development of hippocampal sclerosis.",

author = "Kothare, {Sanjeev V.} and Ana Sotrel and Michael Duchowny and Prasanna Jayakar and Marshall, {Paul C.} and Smith, {Thomas W.}",

year = "2001",

month = jan,

day = "1",

doi = "10.1177/088307380101600804",

language = "English (US)",

volume = "16",

pages = "562--564",

journal = "Journal of Child Neurology",

issn = "0883-0738",

publisher = "SAGE Publications Inc.",

number = "8",

}

TY - JOUR

T1 - Absence of hippocampal sclerosis in children with multiple daily seizures since infancy

AU - Kothare, Sanjeev V.

AU - Sotrel, Ana

AU - Duchowny, Michael

AU - Jayakar, Prasanna

AU - Marshall, Paul C.

AU - Smith, Thomas W.

PY - 2001/1/1

Y1 - 2001/1/1

N2 - We report a series of nine children with multiple daily seizures since infancy who underwent functional hemispherectomy that included en bloc resection of the hippocampus and the temporal neocortex. In all cases, the hippocampi were normal by conventional histology despite the fact that these patients had suffered from recurrent seizures over a long period of time. This observation suggests that extremely frequent seizures in childhood are not invariably associated with the development of hippocampal sclerosis.

AB - We report a series of nine children with multiple daily seizures since infancy who underwent functional hemispherectomy that included en bloc resection of the hippocampus and the temporal neocortex. In all cases, the hippocampi were normal by conventional histology despite the fact that these patients had suffered from recurrent seizures over a long period of time. This observation suggests that extremely frequent seizures in childhood are not invariably associated with the development of hippocampal sclerosis.

UR - http://www.scopus.com/inward/record.url?scp=0034857320&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034857320&partnerID=8YFLogxK

U2 - 10.1177/088307380101600804

DO - 10.1177/088307380101600804

M3 - Article

C2 - 11510925

AN - SCOPUS:0034857320

VL - 16

SP - 562

EP - 564

JO - Journal of Child Neurology

JF - Journal of Child Neurology

SN - 0883-0738

IS - 8

ER -

Absence of hippocampal sclerosis in children with multiple daily seizures since infancy

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this