Abstract
We studied eye movements in 50 patients with Huntington's disease. Fixation was impaired in 73% of patients; such individuals had difficulty in suppressing saccades toward novel visual stimuli. Impaired initiation of saccades was manifest by increased reaction time (89%) and inability to make a saccade without head movements (89%) or blink (35%). Saccades and quick phases of nystagmus were slowed in 62%. Smooth pursuit was abnormal in 60%, and vergence in 33%. The vestibulo-ocular reflex and the ability to hold eccentric gaze were preserved even late in the disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1268-1275 |
| Number of pages | 8 |
| Journal | Neurology |
| Volume | 33 |
| Issue number | 10 |
| DOIs | |
| State | Published - Oct 1983 |
ASJC Scopus subject areas
- Clinical Neurology
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Leigh, R. J., Newma, S. A., Folstein, S. E., Lasker, A. G., & Jensen, B. A. (1983). Abnormal ocular motor control in huntington’s disease. Neurology, 33(10), 1268-1275. https://doi.org/10.1212/wnl.33.10.1268