Aberrant serum enzyme patterns in dermatomyositis associated with hepatoma.

R. G. Gray, R. D. Altman, N. L. Gottlieb

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

A Caucasian male developed florid dermatomyositis documented by serum enzyme elevation, electromyography, and histology of skin and muscle. Serum enzymes, including creatine phosphokinase (CPK), aldolase, glutamic oxaloacetic transaminase (SGOT), and lactic dehydrogenase (LDH), decreased initially during high dose systemic corticosteroid therapy, although profound muscle weakness persisted. Subsequent elevation of serum LDH and SGOT levels during treatment provided a clue to underlying neoplasia. Primary hepatoma with widespread metastases was found at necropsy.

Original languageEnglish (US)
Pages (from-to)227-232
Number of pages6
JournalJournal of Rheumatology
Volume3
Issue number3
StatePublished - Sep 1 1976

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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    Gray, R. G., Altman, R. D., & Gottlieb, N. L. (1976). Aberrant serum enzyme patterns in dermatomyositis associated with hepatoma. Journal of Rheumatology, 3(3), 227-232.