A triphasic analysis of negative osmotic flows through charged hydrated soft tissues

Weiyong Gu, W. M. Lai, V. C. Mow

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

Osmotic flow and ion transport in a one-dimensional steady diffusion process through charged hydrated soft tissues such as articular cartilage were analysed using the triphasic theory. It was found that solvent would flow from the high NaCl concentration side to the low concentration side (i.e. negative osmosis) when the fixed charge density within the tissue (or membrane) separating the two electrolyte (NaCl) solutions was lower than a critical value. The condition for negative osmosis was derived based on a linear version of the triphasic theory. Distributions of ion concentration and strain field within the tissue were calculated numerically. Quantitative results of osmotic flow rates (ordinary and negative osmosis), ion flux and electric potential across the tissue during this diffusion process suggest that the negative osmosis phenomenon is due to the friction between ions and water since they could how through the tissues at different rates and different directions.

Original languageEnglish
Pages (from-to)71-78
Number of pages8
JournalJournal of Biomechanics
Volume30
Issue number1
DOIs
StatePublished - Jan 1 1997
Externally publishedYes

Fingerprint

Osmosis
Tissue
Ions
Friction
Ion Transport
Articular Cartilage
Electrolytes
Cartilage
Charge density
Membranes
Flow rate
Water
Fluxes
Electric potential

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this

A triphasic analysis of negative osmotic flows through charged hydrated soft tissues. / Gu, Weiyong; Lai, W. M.; Mow, V. C.

In: Journal of Biomechanics, Vol. 30, No. 1, 01.01.1997, p. 71-78.

Research output: Contribution to journalArticle

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