A translocation t(9;11)(p11;q23) in T-cell acute lymphoblastic leukemia (FAB-L2)

Yao Shan Fan, Jacob M. Rowe, Paola Dal Cin, Avery A. Sandberg

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

We here report a t(9;11)(p11;q23) as the only abnormality in the affected cells of a 20-year-old male with acute lymphoblastic leukemia (L2) of T-cell origin. One hundred six patients with acute leukemia and involvement of band 11q23 were reviewed. Young age, hyperleukocytosis, and poor prognosis characterized almost all the cases in the acute leukemias with the 11q23 translocation, despite involvement of different recipient chromosomes and different morphologic and immunologic phenotypes.

Original languageEnglish (US)
Pages (from-to)263-269
Number of pages7
JournalCancer Genetics and Cytogenetics
Volume31
Issue number2
DOIs
StatePublished - Apr 1988
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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