A tissue phantom for investigating volume quantification on retinal images obtained with the stratus OCT system

Delia Cabrera DeBuc, H. M. Salinas

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

The performance of the Stratus OCT system in extracting shape and volume of retinal lesions was investigated by scanning a tissue phantom containing specific enclosed geometric gaps of known size. Measurements were made by filling the gaps with an aqueous suspension containing a fixed tissue suspended in phosphate-buffered saline inside the gaps. OCT raw data was exported for subsequent analysis using custom software written in MATLAB software platform. An active contour model was used to outline the boundaries of the fixed tissue on OCT images of the tissue phantom. Images provided by the OCT system were analyzed with the custom software and later compared with the actual geometric parameters of the tissue phantom. An active contour model is effective in detecting the boundaries of the tested object and accurately estimating its volume. We show that a tissue phantom provides an easy and reproducible method of verifying the accuracy and precision of specific features in the images retrieved by the Stratus OCT system.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages1225-1228
Number of pages4
Volume26 II
StatePublished - 2004
EventConference Proceedings - 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2004 - San Francisco, CA, United States
Duration: Sep 1 2004Sep 5 2004

Other

OtherConference Proceedings - 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2004
CountryUnited States
CitySan Francisco, CA
Period9/1/049/5/04

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Tissue
MATLAB
Suspensions
Phosphates
Scanning

Keywords

  • Image processing
  • Light propagation in tissue
  • Optical coherence tomography
  • Retina
  • Tissue phantom
  • Volume quantification

ASJC Scopus subject areas

  • Bioengineering

Cite this

Cabrera DeBuc, D., & Salinas, H. M. (2004). A tissue phantom for investigating volume quantification on retinal images obtained with the stratus OCT system. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 26 II, pp. 1225-1228)

A tissue phantom for investigating volume quantification on retinal images obtained with the stratus OCT system. / Cabrera DeBuc, Delia; Salinas, H. M.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 26 II 2004. p. 1225-1228.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Cabrera DeBuc, D & Salinas, HM 2004, A tissue phantom for investigating volume quantification on retinal images obtained with the stratus OCT system. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 26 II, pp. 1225-1228, Conference Proceedings - 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2004, San Francisco, CA, United States, 9/1/04.
Cabrera DeBuc D, Salinas HM. A tissue phantom for investigating volume quantification on retinal images obtained with the stratus OCT system. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 26 II. 2004. p. 1225-1228
Cabrera DeBuc, Delia ; Salinas, H. M. / A tissue phantom for investigating volume quantification on retinal images obtained with the stratus OCT system. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 26 II 2004. pp. 1225-1228
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