A Surgeon's Guide to the Various Antibiotic Dips Available During Penile Prosthesis Implantation

Soum D. Lokeshwar, Joshua Bitran, Vinayak Madhusoodanan, Bruce Kava, Ranjith Ramasamy

Research output: Contribution to journalReview article

8 Scopus citations

Abstract

Purpose of Review: Inflatable penile prosthesis (IPP) is a treatment for erectile dysfunction. IPPs have undergone improvements; however, post-surgical infections still occur. Furthermore, the type of pathogens infecting the implants has changed recently from Gram-positive to Gram-negative bacteria and fungi due to advances in antibiotic dips targeting the skin flora. To protect against infection, the AMS 700 is pre-coated with InhibiZone (mixture of Rifampin/Minocycline) and the Coloplast Titan, with several antibiotic dip options of differing efficacies. This review discusses strategies to decrease the infection rates in implant surgery, focusing on antibiotic dips. Recent Findings: Current research endorses the use of rifampin/gentamicin as the most studied combination; however, some studies have utilized different dips for additional coverage including the InhibiZone on the AMS 700. Summary: With the increasing prevalence of diabetes and Gram-negative organisms, there is a need to develop strategies for increased coverage against infections. Controlled studies with different antibiotic combinations are needed to identify the ideal cocktail to decrease infection.

Original languageEnglish (US)
Article number11
JournalCurrent Urology Reports
Volume20
Issue number2
DOIs
StatePublished - Feb 1 2019

Keywords

  • Antibiotic dips
  • IPPs (inflatable penile prosthesis)
  • Penile implant infections
  • Penile implant surgery

ASJC Scopus subject areas

  • Urology

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