Abstract
Purpose of Review: Inflatable penile prosthesis (IPP) is a treatment for erectile dysfunction. IPPs have undergone improvements; however, post-surgical infections still occur. Furthermore, the type of pathogens infecting the implants has changed recently from Gram-positive to Gram-negative bacteria and fungi due to advances in antibiotic dips targeting the skin flora. To protect against infection, the AMS 700 is pre-coated with InhibiZone (mixture of Rifampin/Minocycline) and the Coloplast Titan, with several antibiotic dip options of differing efficacies. This review discusses strategies to decrease the infection rates in implant surgery, focusing on antibiotic dips. Recent Findings: Current research endorses the use of rifampin/gentamicin as the most studied combination; however, some studies have utilized different dips for additional coverage including the InhibiZone on the AMS 700. Summary: With the increasing prevalence of diabetes and Gram-negative organisms, there is a need to develop strategies for increased coverage against infections. Controlled studies with different antibiotic combinations are needed to identify the ideal cocktail to decrease infection.
| Original language | English (US) |
|---|---|
| Article number | 11 |
| Journal | Current Urology Reports |
| Volume | 20 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 1 2019 |
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Keywords
- Antibiotic dips
- IPPs (inflatable penile prosthesis)
- Penile implant infections
- Penile implant surgery
ASJC Scopus subject areas
- Urology
Cite this
A Surgeon's Guide to the Various Antibiotic Dips Available During Penile Prosthesis Implantation. / Lokeshwar, Soum D.; Bitran, Joshua; Madhusoodanan, Vinayak; Kava, Bruce; Ramasamy, Ranjith.
In: Current Urology Reports, Vol. 20, No. 2, 11, 01.02.2019.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - A Surgeon's Guide to the Various Antibiotic Dips Available During Penile Prosthesis Implantation
AU - Lokeshwar, Soum D.
AU - Bitran, Joshua
AU - Madhusoodanan, Vinayak
AU - Kava, Bruce
AU - Ramasamy, Ranjith
PY - 2019/2/1
Y1 - 2019/2/1
N2 - Purpose of Review: Inflatable penile prosthesis (IPP) is a treatment for erectile dysfunction. IPPs have undergone improvements; however, post-surgical infections still occur. Furthermore, the type of pathogens infecting the implants has changed recently from Gram-positive to Gram-negative bacteria and fungi due to advances in antibiotic dips targeting the skin flora. To protect against infection, the AMS 700 is pre-coated with InhibiZone (mixture of Rifampin/Minocycline) and the Coloplast Titan, with several antibiotic dip options of differing efficacies. This review discusses strategies to decrease the infection rates in implant surgery, focusing on antibiotic dips. Recent Findings: Current research endorses the use of rifampin/gentamicin as the most studied combination; however, some studies have utilized different dips for additional coverage including the InhibiZone on the AMS 700. Summary: With the increasing prevalence of diabetes and Gram-negative organisms, there is a need to develop strategies for increased coverage against infections. Controlled studies with different antibiotic combinations are needed to identify the ideal cocktail to decrease infection.
AB - Purpose of Review: Inflatable penile prosthesis (IPP) is a treatment for erectile dysfunction. IPPs have undergone improvements; however, post-surgical infections still occur. Furthermore, the type of pathogens infecting the implants has changed recently from Gram-positive to Gram-negative bacteria and fungi due to advances in antibiotic dips targeting the skin flora. To protect against infection, the AMS 700 is pre-coated with InhibiZone (mixture of Rifampin/Minocycline) and the Coloplast Titan, with several antibiotic dip options of differing efficacies. This review discusses strategies to decrease the infection rates in implant surgery, focusing on antibiotic dips. Recent Findings: Current research endorses the use of rifampin/gentamicin as the most studied combination; however, some studies have utilized different dips for additional coverage including the InhibiZone on the AMS 700. Summary: With the increasing prevalence of diabetes and Gram-negative organisms, there is a need to develop strategies for increased coverage against infections. Controlled studies with different antibiotic combinations are needed to identify the ideal cocktail to decrease infection.
KW - Antibiotic dips
KW - IPPs (inflatable penile prosthesis)
KW - Penile implant infections
KW - Penile implant surgery
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UR - http://www.scopus.com/inward/citedby.url?scp=85060893120&partnerID=8YFLogxK
U2 - 10.1007/s11934-019-0874-8
DO - 10.1007/s11934-019-0874-8
M3 - Review article
C2 - 30701340
AN - SCOPUS:85060893120
VL - 20
JO - Current Urology Reports
JF - Current Urology Reports
SN - 1527-2737
IS - 2
M1 - 11
ER -