A spontaneous outbreak of polychlorinated biphenyl (PCB) toxicity in rhesus monkeys (Macaca mulatta): Clinical observations

N. H. Altman; A. E. New; E. E. McConnell; T. L. Ferrell

A spontaneous outbreak of polychlorinated biphenyl (PCB) toxicity in rhesus monkeys (Macaca mulatta)

Clinical observations

N. H. Altman, A. E. New, E. E. McConnell, T. L. Ferrell

Research output: Chapter in Book/Report/Conference proceeding › Chapter

15 Citations (Scopus)

Abstract

A spontaneous, progressive disease occurred in a large domestic breeding colony of rhesus monkeys (Macaca mulatta). The disease was characterized by slow but continuous weight loss, alopecia, acne, facial edema, diarrhea and trauma from other monkeys. Breeding efficiency was impaired with a high incidence of abortions and stillbirths. Live offspring were small and unthrifty contributing to a high infant mortality rate. The cause of this disease was polychlorinated biphenyls (PCBs) which were present in the concrete sealant on the cage floors. Removing the sealant and resurfacing the floors alleviated the problem.

Original language	English
Title of host publication	Laboratory Animal Science
Pages	661-665
Number of pages	5
Volume	29
Edition	5
State	Published - Dec 1 1979
Externally published	Yes

Fingerprint

Polychlorinated Biphenyls

Macaca mulatta

Disease Outbreaks

Breeding

Stillbirth

Alopecia

Acne Vulgaris

Infant Mortality

Haplorhini

Weight Loss

Diarrhea

Edema

Mortality

Incidence

Wounds and Injuries

ASJC Scopus subject areas

Medicine(all)

Cite this

Altman, N. H., New, A. E., McConnell, E. E., & Ferrell, T. L. (1979). A spontaneous outbreak of polychlorinated biphenyl (PCB) toxicity in rhesus monkeys (Macaca mulatta): Clinical observations. In Laboratory Animal Science (5 ed., Vol. 29, pp. 661-665)

A spontaneous outbreak of polychlorinated biphenyl (PCB) toxicity in rhesus monkeys (Macaca mulatta) : Clinical observations. / Altman, N. H.; New, A. E.; McConnell, E. E.; Ferrell, T. L.

Laboratory Animal Science. Vol. 29 5. ed. 1979. p. 661-665.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Altman, NH, New, AE, McConnell, EE & Ferrell, TL 1979, A spontaneous outbreak of polychlorinated biphenyl (PCB) toxicity in rhesus monkeys (Macaca mulatta): Clinical observations. in Laboratory Animal Science. 5 edn, vol. 29, pp. 661-665.

Altman NH, New AE, McConnell EE, Ferrell TL. A spontaneous outbreak of polychlorinated biphenyl (PCB) toxicity in rhesus monkeys (Macaca mulatta): Clinical observations. In Laboratory Animal Science. 5 ed. Vol. 29. 1979. p. 661-665

Altman, N. H. ; New, A. E. ; McConnell, E. E. ; Ferrell, T. L. / A spontaneous outbreak of polychlorinated biphenyl (PCB) toxicity in rhesus monkeys (Macaca mulatta) : Clinical observations. Laboratory Animal Science. Vol. 29 5. ed. 1979. pp. 661-665

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