A solid phase C1q enzyme assay for circulating immune complexes adapted for routine clinical laboratory testing

K. James, A. Vahey, M. Robinson, R. Marder

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

An assay for circulating immune complexes (CIC) that is adaptable to a routine clinical laboratory is described. This solid phase C1q (SP C1q) enzyme immunoassay (EIA) uses commercially available reagents and is reproducible with CV% of <20% in the abnormal range. We also demonstrate the specificity of the assay for detecting clinically relevant dsDNA-anti-DNA immune complexes.

Original languageEnglish (US)
Pages (from-to)445-452
Number of pages8
JournalAmerican journal of clinical pathology
Volume80
Issue number4
DOIs
StatePublished - Jan 1 1983

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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