A solid phase C1q enzyme assay for circulating immune complexes adapted for routine clinical laboratory testing

K. James; A. Vahey; M. Robinson; R. Marder

doi:10.1093/ajcp/80.4.445

A solid phase C1q enzyme assay for circulating immune complexes adapted for routine clinical laboratory testing

K. James, A. Vahey, M. Robinson, R. Marder

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3 Scopus citations

Abstract

An assay for circulating immune complexes (CIC) that is adaptable to a routine clinical laboratory is described. This solid phase C1q (SP C1q) enzyme immunoassay (EIA) uses commercially available reagents and is reproducible with CV% of <20% in the abnormal range. We also demonstrate the specificity of the assay for detecting clinically relevant dsDNA-anti-DNA immune complexes.

Original language	English (US)
Pages (from-to)	445-452
Number of pages	8
Journal	American journal of clinical pathology
Volume	80
Issue number	4
DOIs	https://doi.org/10.1093/ajcp/80.4.445
State	Published - 1983
Externally published	Yes

ASJC Scopus subject areas

Pathology and Forensic Medicine

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10.1093/ajcp/80.4.445

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abstract = "An assay for circulating immune complexes (CIC) that is adaptable to a routine clinical laboratory is described. This solid phase C1q (SP C1q) enzyme immunoassay (EIA) uses commercially available reagents and is reproducible with CV% of <20% in the abnormal range. We also demonstrate the specificity of the assay for detecting clinically relevant dsDNA-anti-DNA immune complexes.",

author = "K. James and A. Vahey and M. Robinson and R. Marder",

year = "1983",

doi = "10.1093/ajcp/80.4.445",

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AU - Vahey, A.

AU - Robinson, M.

AU - Marder, R.

PY - 1983

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N2 - An assay for circulating immune complexes (CIC) that is adaptable to a routine clinical laboratory is described. This solid phase C1q (SP C1q) enzyme immunoassay (EIA) uses commercially available reagents and is reproducible with CV% of <20% in the abnormal range. We also demonstrate the specificity of the assay for detecting clinically relevant dsDNA-anti-DNA immune complexes.

AB - An assay for circulating immune complexes (CIC) that is adaptable to a routine clinical laboratory is described. This solid phase C1q (SP C1q) enzyme immunoassay (EIA) uses commercially available reagents and is reproducible with CV% of <20% in the abnormal range. We also demonstrate the specificity of the assay for detecting clinically relevant dsDNA-anti-DNA immune complexes.

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A solid phase C1q enzyme assay for circulating immune complexes adapted for routine clinical laboratory testing

Abstract

ASJC Scopus subject areas

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