A solid phase C1q enzyme assay for circulating immune complexes adapted for routine clinical laboratory testing

K. James; A. Vahey; M. Robinson; R. Marder

doi:10.1093/ajcp/80.4.445

A solid phase C1q enzyme assay for circulating immune complexes adapted for routine clinical laboratory testing

K. James, A. Vahey, M. Robinson, R. Marder

Pathology

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

An assay for circulating immune complexes (CIC) that is adaptable to a routine clinical laboratory is described. This solid phase C1q (SP C1q) enzyme immunoassay (EIA) uses commercially available reagents and is reproducible with CV% of <20% in the abnormal range. We also demonstrate the specificity of the assay for detecting clinically relevant dsDNA-anti-DNA immune complexes.

Original language	English (US)
Pages (from-to)	445-452
Number of pages	8
Journal	American journal of clinical pathology
Volume	80
Issue number	4
DOIs	https://doi.org/10.1093/ajcp/80.4.445
State	Published - Jan 1 1983

ASJC Scopus subject areas

Pathology and Forensic Medicine

Access to Document

10.1093/ajcp/80.4.445

Cite this

@article{eaeaa537add641f0a6ad520ea1be15b2,

title = "A solid phase C1q enzyme assay for circulating immune complexes adapted for routine clinical laboratory testing",

abstract = "An assay for circulating immune complexes (CIC) that is adaptable to a routine clinical laboratory is described. This solid phase C1q (SP C1q) enzyme immunoassay (EIA) uses commercially available reagents and is reproducible with CV% of <20% in the abnormal range. We also demonstrate the specificity of the assay for detecting clinically relevant dsDNA-anti-DNA immune complexes.",

author = "K. James and A. Vahey and M. Robinson and R. Marder",

year = "1983",

month = jan,

day = "1",

doi = "10.1093/ajcp/80.4.445",

language = "English (US)",

volume = "80",

pages = "445--452",

journal = "American Journal of Clinical Pathology",

issn = "0002-9173",

publisher = "American Society of Clinical Pathologists",

number = "4",

}

TY - JOUR

T1 - A solid phase C1q enzyme assay for circulating immune complexes adapted for routine clinical laboratory testing

AU - James, K.

AU - Vahey, A.

AU - Robinson, M.

AU - Marder, R.

PY - 1983/1/1

Y1 - 1983/1/1

N2 - An assay for circulating immune complexes (CIC) that is adaptable to a routine clinical laboratory is described. This solid phase C1q (SP C1q) enzyme immunoassay (EIA) uses commercially available reagents and is reproducible with CV% of <20% in the abnormal range. We also demonstrate the specificity of the assay for detecting clinically relevant dsDNA-anti-DNA immune complexes.

AB - An assay for circulating immune complexes (CIC) that is adaptable to a routine clinical laboratory is described. This solid phase C1q (SP C1q) enzyme immunoassay (EIA) uses commercially available reagents and is reproducible with CV% of <20% in the abnormal range. We also demonstrate the specificity of the assay for detecting clinically relevant dsDNA-anti-DNA immune complexes.

UR - http://www.scopus.com/inward/record.url?scp=0020602193&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020602193&partnerID=8YFLogxK

U2 - 10.1093/ajcp/80.4.445

DO - 10.1093/ajcp/80.4.445

M3 - Article

C2 - 6353904

AN - SCOPUS:0020602193

VL - 80

SP - 445

EP - 452

JO - American Journal of Clinical Pathology

JF - American Journal of Clinical Pathology

SN - 0002-9173

IS - 4

ER -

A solid phase C1q enzyme assay for circulating immune complexes adapted for routine clinical laboratory testing

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this