A simple, effective mixing chamber used in conjunction with a syringe pump for flow analysis

Natchanon Amornthammarong, Peter B. Ortner, Jia Zhong Zhang

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

A simple, effective mixing chamber used in conjunction with a syringe pump for flow analysis is described and evaluated. A mixing chamber was constructed using a conventional 5 mL pipette tip and its performance compared with a widely used mixing coil. The results demonstrate that the mixing coil does not rapidly and completely mix solutions. Utilizing a configuration that reversed solution positions in the chamber with each mixing cycle, the proposed mixing chamber achieved complete mixing in a significantly shorter time than the mixing coil. The influence of injected sample volume on absorbance signals was evaluated by calculating an S1/2 value for the system. As tested with a minimal rinse, the system has no discernable carryover. Testing this new approach in our previously described silicate measurement system resulted in a more than twofold improvement in sensitivity.

Original languageEnglish (US)
Pages (from-to)1472-1476
Number of pages5
JournalTalanta
Volume81
Issue number4-5
DOIs
StatePublished - Jun 15 2010

Keywords

  • Flow analysis
  • Mixing chamber
  • Mixing coil
  • Mixing efficiency
  • Syringe pump

ASJC Scopus subject areas

  • Chemistry(all)

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