Abstract
A simple, effective mixing chamber used in conjunction with a syringe pump for flow analysis is described and evaluated. A mixing chamber was constructed using a conventional 5 mL pipette tip and its performance compared with a widely used mixing coil. The results demonstrate that the mixing coil does not rapidly and completely mix solutions. Utilizing a configuration that reversed solution positions in the chamber with each mixing cycle, the proposed mixing chamber achieved complete mixing in a significantly shorter time than the mixing coil. The influence of injected sample volume on absorbance signals was evaluated by calculating an S1/2 value for the system. As tested with a minimal rinse, the system has no discernable carryover. Testing this new approach in our previously described silicate measurement system resulted in a more than twofold improvement in sensitivity.
Original language | English (US) |
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Pages (from-to) | 1472-1476 |
Number of pages | 5 |
Journal | Talanta |
Volume | 81 |
Issue number | 4-5 |
DOIs | |
State | Published - Jun 15 2010 |
Keywords
- Flow analysis
- Mixing chamber
- Mixing coil
- Mixing efficiency
- Syringe pump
ASJC Scopus subject areas
- Chemistry(all)