A review of the iStent® trabecular micro-bypass stent: Safety and efficacy

Sarah R. Wellik, Elizabeth A. Dale

Research output: Contribution to journalReview articlepeer-review

36 Scopus citations


There is a significant demand for procedures that can effectively treat glaucoma with low risk and good visual outcomes. To fill this void, procedures termed “minimally invasive glaucoma surgery”, are gaining in popularity. This review will focus on the safety and efficacy of one such minimally invasive glaucoma surgery procedure, the trabecular micro-bypass stent. This stent is intended to lower intraocular pressure by directly cannulating Schlemm’s canal and thereby enhancing aqueous outflow. Recent randomized controlled trials and case series have demonstrated the micro-bypass stent to be a relatively safe procedure, with limited complications and no serious adverse sequelae. The most common complication across all studies was stent obstruction or malposition, which generally did not result in any adverse outcome in vision or pressure control. In addition, increased rates of hypotony, choroidal hemorrhage, or infection were not seen with the micro-bypass stent in comparison to cataract surgery alone.

Original languageEnglish (US)
Pages (from-to)677-684
Number of pages8
JournalClinical Ophthalmology
StatePublished - Apr 15 2015


  • Glaucoma
  • MIGS
  • Minimally invasive glaucoma surgery
  • Schlemm’s canal

ASJC Scopus subject areas

  • Ophthalmology


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