A review of kidney transplantation from HCV-viremic donors into HCV-negative recipients

Reem Daloul, Todd E. Pesavento, David S. Goldberg, Peter P. Reese

Research output: Contribution to journalReview articlepeer-review

Abstract

The safety and efficacy of direct-acting antiviral therapies have allowed the transplantation of organs from hepatitis C virus (HCV)–viremic donors into uninfected recipients. This novel strategy contrasts with the previous standard-of-care practice of limiting the transplantation of HCV infected–donor organs to HCV-infected recipients, or all too often, discarding viable organs. In this review, we summarize the published literature about the safety and feasibility of transplanting organs from HCV-viremic donors, the challenges that hinder wider adoption of this strategy, and future research needs.

Original languageEnglish (US)
Pages (from-to)1190-1198
Number of pages9
JournalKidney international
Volume100
Issue number6
DOIs
StatePublished - Dec 2021

Keywords

  • antiviral agents
  • deceased donor
  • hepacivirus
  • hepatitis C
  • kidney transplantation
  • tissue donor

ASJC Scopus subject areas

  • Nephrology

Fingerprint

Dive into the research topics of 'A review of kidney transplantation from HCV-viremic donors into HCV-negative recipients'. Together they form a unique fingerprint.

Cite this