A retrospective comparison of primary baerveldt implantation versus trabeculectomy with mitomycin C

Joseph F. Panarelli, Michael R. Banitt, Steven J. Gedde, Wei Shi, Joyce C. Schiffman, William J. Feuer

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Purpose To compare the safety and efficacy of Baerveldt implantation (Abbott Medical Optics, Santa Ana, CA) and trabeculectomy with mitomycin C (MMC) in patients who have not undergone prior incisional ocular surgery. Design Retrospective, comparative case series. Participants A total of 125 patients with low-risk glaucoma undergoing primary glaucoma surgery, including 55 patients who received a 350-mm2 Baerveldt glaucoma implant and 70 patients who underwent trabeculectomy with MMC. Methods Eligible patients were identified using Current Procedural Terminology codes, and their medical records were reviewed retrospectively. Main Outcome Measures The primary outcome measure was surgical success (intraocular pressure [IOP] ≤21 mmHg and reduced ≥20% from baseline, IOP >5 mmHg, no reoperation for glaucoma, no loss of light-perception vision). Secondary outcome measures included visual acuity, IOP, number of glaucoma medications, and complications. Results The cumulative probability of success at 3 years with or without medical therapy was 87% in the Baerveldt group and 76% in the trabeculectomy group (P = 0.23). Postoperative complications occurred in 11 patients (20%) in the Baerveldt group and 20 patients (29%) in the trabeculectomy group (P = 0.27). Mean follow-up ± standard deviation was 27±19 months in the Baerveldt group and 34±20 months in the trabeculectomy group (P = 0.053). Conclusions Similar rates of surgical success and postoperative complications were observed in patients undergoing trabeculectomy with MMC and in those undergoing Baerveldt implantation during 3 years of follow-up. Both are viable primary glaucoma procedures in patients who have not undergone prior ocular surgery.

Original languageEnglish (US)
Pages (from-to)789-795
Number of pages7
JournalOphthalmology
Volume123
Issue number4
DOIs
StatePublished - Apr 1 2016

ASJC Scopus subject areas

  • Ophthalmology

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