A retrospective analysis of the effects of anticholinergic medication on memory performance in Parkinson's disease

B. E. Levin, M. M. Llabre, S. Reisman, W. J. Weiner, M. C. Brown

Research output: Contribution to journalArticle

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Abstract

We examined the effects of anticholinergic medication on memory function in 113 patients with idiopathic Parkinson's disease (PD). Subjects were divided into three disease duration groups: early, middle, and advanced. The battery consisted of three tasks assessing memory of logical discourse, semantically related words, and figural material. We found no evidence of anticholinergic-induced memory dysfunction in any of the three groups. Analysis of covariance indicated that age was not a significant variable; however, dementia may have influenced the relationship between anticholinergic medication and memory scores. Our results indicate that anticholinergic medication does not uniformly compromise memory function in PD patients.

Original languageEnglish (US)
Pages (from-to)412-416
Number of pages5
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Volume3
Issue number4
DOIs
StatePublished - Jan 1 1991

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ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health

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