A reduced dose of zidovudine in patients with AIDS

Raymond C.y. Chung, S. Escolano, J. L. Golmard, A. Mallet, Margaret A. Fischl, Anastasios Tsiatis, Ann C. Collier, Teresa Tartaglione, Lawrence Corey

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Abstract

To the Editor: The article by Fischl et al. (Oct. 11 issue)* is a very important contribution to the literature on the use of zidovudine in patients with the acquired immunodeficiency syndrome (AIDS). The data presented have already substantially affected the day-to-day care of patients with human immunodeficiency virus (HIV) infection. The study was designed to use an intention-to-treat analysis of the data. Was there a difference in the incidence of opportunistic infections and death between the standard-treatment group and the low-dose group when the results for those who remained on therapy were analyzed? This question is important, because patients.

Original languageEnglish (US)
Pages (from-to)994-996
Number of pages3
JournalNew England Journal of Medicine
Volume324
Issue number14
DOIs
StatePublished - Apr 4 1991

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Chung, R. C. Y., Escolano, S., Golmard, J. L., Mallet, A., Fischl, M. A., Tsiatis, A., Collier, A. C., Tartaglione, T., & Corey, L. (1991). A reduced dose of zidovudine in patients with AIDS. New England Journal of Medicine, 324(14), 994-996. https://doi.org/10.1056/NEJM199104043241414