A reduced dose of zidovudine in patients with AIDS

Raymond C.y. Chung, S. Escolano, J. L. Golmard, A. Mallet, Margaret A Fischl, Anastasios Tsiatis, Ann C. Collier, Teresa Tartaglione, Lawrence Corey

Research output: Contribution to journalLetter

8 Citations (Scopus)

Abstract

To the Editor: The article by Fischl et al. (Oct. 11 issue)* is a very important contribution to the literature on the use of zidovudine in patients with the acquired immunodeficiency syndrome (AIDS). The data presented have already substantially affected the day-to-day care of patients with human immunodeficiency virus (HIV) infection. The study was designed to use an intention-to-treat analysis of the data. Was there a difference in the incidence of opportunistic infections and death between the standard-treatment group and the low-dose group when the results for those who remained on therapy were analyzed? This question is important, because patients.

Original languageEnglish (US)
Pages (from-to)994-996
Number of pages3
JournalNew England Journal of Medicine
Volume324
Issue number14
DOIs
StatePublished - Apr 4 1991

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Zidovudine
Acquired Immunodeficiency Syndrome
Intention to Treat Analysis
Opportunistic Infections
Virus Diseases
HIV
Incidence
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Chung, R. C. Y., Escolano, S., Golmard, J. L., Mallet, A., Fischl, M. A., Tsiatis, A., ... Corey, L. (1991). A reduced dose of zidovudine in patients with AIDS. New England Journal of Medicine, 324(14), 994-996. https://doi.org/10.1056/NEJM199104043241414

A reduced dose of zidovudine in patients with AIDS. / Chung, Raymond C.y.; Escolano, S.; Golmard, J. L.; Mallet, A.; Fischl, Margaret A; Tsiatis, Anastasios; Collier, Ann C.; Tartaglione, Teresa; Corey, Lawrence.

In: New England Journal of Medicine, Vol. 324, No. 14, 04.04.1991, p. 994-996.

Research output: Contribution to journalLetter

Chung, RCY, Escolano, S, Golmard, JL, Mallet, A, Fischl, MA, Tsiatis, A, Collier, AC, Tartaglione, T & Corey, L 1991, 'A reduced dose of zidovudine in patients with AIDS', New England Journal of Medicine, vol. 324, no. 14, pp. 994-996. https://doi.org/10.1056/NEJM199104043241414
Chung RCY, Escolano S, Golmard JL, Mallet A, Fischl MA, Tsiatis A et al. A reduced dose of zidovudine in patients with AIDS. New England Journal of Medicine. 1991 Apr 4;324(14):994-996. https://doi.org/10.1056/NEJM199104043241414
Chung, Raymond C.y. ; Escolano, S. ; Golmard, J. L. ; Mallet, A. ; Fischl, Margaret A ; Tsiatis, Anastasios ; Collier, Ann C. ; Tartaglione, Teresa ; Corey, Lawrence. / A reduced dose of zidovudine in patients with AIDS. In: New England Journal of Medicine. 1991 ; Vol. 324, No. 14. pp. 994-996.
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