A questionnaire-based (UM-PDHQ) study of hallucinations in Parkinson's disease

Spiridon Papapetropoulos, Heather Katzen, Anette Schrag, Carlos Singer, Blake K. Scanlon, Daniel Nation, Alexandra Guevara, Bonnie Levin

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Background: Hallucinations occur in 20-40% of PD patients and have been associated with unfavorable clinical outcomes (i.e., nursing home placement, increased mortality). Hallucinations, like other non-motor features of PD, are not well recognized in routine primary/secondary clinical practice. So far, there has been no instrument for uniform characterization of hallucinations in PD. To this end, we developed the University of Miami Parkinson's disease Hallucinations Questionnaire (UM-PDHQ) that allows comprehensive assessment of hallucinations in clinical or research settings. Methods: The UM-PDHQ is composed of 6 quantitative and 14 qualitative items. For our study PD patients of all ages and in all stages of the disease were recruited over an 18-month period. The UPDRS, MMSE, and Beck Depression and Anxiety Inventories were used for comparisons. Results and Discussion: Seventy consecutive PD patients were included in the analyses. Thirty-one (44.3%) were classified as hallucinators and 39 as non-hallucinators. No significant group differences were observed in terms of demographics, disease characteristics, stage, education, depressive/anxiety scores or cognitive functioning (MMSE) between hallucinators and non-hallucinators. Single mode hallucinations were reported in 20/31 (visual/14, auditory/4, olfactory/2) whereas multiple modalities were reported in 11/31 patients. The most common hallucinatory experience was a whole person followed by small animals, insects and reptiles. Conclusion: Using the UM-PDHQ, we were able to define the key characteristics of hallucinations in PD in our cohort. Future directions include the validation of the quantitative part of the questionnaire than will serve as a rating scale for severity of hallucinations.

Original languageEnglish
Article number21
JournalBMC Neurology
Volume8
DOIs
StatePublished - Jun 20 2008

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Hallucinations
Parkinson Disease
Anxiety
Surveys and Questionnaires
Reptiles
Nursing Homes
Insects
Demography
Depression
Education
Equipment and Supplies
Mortality

ASJC Scopus subject areas

  • Medicine(all)
  • Clinical Neurology

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A questionnaire-based (UM-PDHQ) study of hallucinations in Parkinson's disease. / Papapetropoulos, Spiridon; Katzen, Heather; Schrag, Anette; Singer, Carlos; Scanlon, Blake K.; Nation, Daniel; Guevara, Alexandra; Levin, Bonnie.

In: BMC Neurology, Vol. 8, 21, 20.06.2008.

Research output: Contribution to journalArticle

Papapetropoulos, S, Katzen, H, Schrag, A, Singer, C, Scanlon, BK, Nation, D, Guevara, A & Levin, B 2008, 'A questionnaire-based (UM-PDHQ) study of hallucinations in Parkinson's disease', BMC Neurology, vol. 8, 21. https://doi.org/10.1186/1471-2377-8-21
Papapetropoulos, Spiridon ; Katzen, Heather ; Schrag, Anette ; Singer, Carlos ; Scanlon, Blake K. ; Nation, Daniel ; Guevara, Alexandra ; Levin, Bonnie. / A questionnaire-based (UM-PDHQ) study of hallucinations in Parkinson's disease. In: BMC Neurology. 2008 ; Vol. 8.
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