A prospective study of sensory function in patients with Type 2 diabetes

Jay M Sosenko, M. Kato, R. Soto, D. E. Bild

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Sensory function was prospectively examined in 201 Type 2 diabetic patients over a 2-year period. Quantitative sensory testing for vibration, cool, warm, and pressure perception at the hallux was performed at baseline, 1-month, 1-year, and 2-year visits. There were statistically significant increments of thresholds for all sensory modalities from the baseline visit to the 1-year visit (p < 0.001) and from the 1-year visit to the 2-year visit (p < 0.001). Thirty percent of 77 subjects considered to be at low risk for foot ulceration at baseline progressed to a higher risk category at the 2-year visit. There were no significant differences in mean glycosylated haemoglobin, height, sex distribution, age, or diabetes duration when patients who had a faster progression of insensitivity were compared with patients who had a slower progression. There was a high degree of autocorrelation between baseline and 2-year visits for all sensory modalities (r = 0.83 to r = 0.88, p < 0.001 for all). Also, changes in sensory thresholds from the baseline to 2-year visits for one modality tended to correlate with other modalities (r = 0.36 to r = 0.70, p < 0.001 for all). These data indicate that an appreciable proportion of Type 2 diabetic patients are at risk for a marked rate of decline of sensory function, and suggest a need for at least yearly quantitative sensory testing.

Original languageEnglish
Pages (from-to)110-114
Number of pages5
JournalDiabetic Medicine
Volume10
Issue number2
StatePublished - Jan 1 1993

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Type 2 Diabetes Mellitus
Prospective Studies
Sensory Thresholds
Hallux
Sex Distribution
Glycosylated Hemoglobin A
Vibration
Foot
Pressure

Keywords

  • diabetic neuropathy
  • glycosylated haemoglobin
  • Type 2 diabetes

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

Cite this

A prospective study of sensory function in patients with Type 2 diabetes. / Sosenko, Jay M; Kato, M.; Soto, R.; Bild, D. E.

In: Diabetic Medicine, Vol. 10, No. 2, 01.01.1993, p. 110-114.

Research output: Contribution to journalArticle

Sosenko, JM, Kato, M, Soto, R & Bild, DE 1993, 'A prospective study of sensory function in patients with Type 2 diabetes', Diabetic Medicine, vol. 10, no. 2, pp. 110-114.
Sosenko, Jay M ; Kato, M. ; Soto, R. ; Bild, D. E. / A prospective study of sensory function in patients with Type 2 diabetes. In: Diabetic Medicine. 1993 ; Vol. 10, No. 2. pp. 110-114.
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