A prospective randomized trial to assess fixation strategies for severe open tibia fractures: Modern ring external fixators versus internal fixation (FIXIT Study)

METRC

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The treatment of high-energy open tibia fractures is challenging in both the military and civilian environments. Treatment with modern ring external fixation may reduce complications common in these patients. However, no study has rigorously compared outcomes of modern ring external fixation with commonly used internal fixation approaches. The FIXIT study is a prospective, multicenter randomized trial comparing 1-year outcomes after treatment of severe open tibial shaft fractures with modern external ring fixation versus internal fixation among men and women of ages 18-64. The primary outcome is rehospitalization for major limb complications. Secondary outcomes include infection, fracture healing, limb function, and patient-reported outcomes including physical function and pain. One-year treatment costs and patient satisfaction will be compared between the 2 groups, and the percentage of Gustilo IIIB fractures that can be salvaged without soft tissue flap among patients receiving external fixation will be estimated.

Original languageEnglish (US)
Pages (from-to)S10-S17
JournalJournal of Orthopaedic Trauma
Volume31
DOIs
StatePublished - 2017

Fingerprint

External Fixators
Open Fractures
Tibia
Extremities
Tibial Fractures
Fracture Healing
Patient Satisfaction
Health Care Costs
Multicenter Studies
Pain
Therapeutics
Infection
Patient Reported Outcome Measures

Keywords

  • External ring fixation
  • Internal fixation
  • Open tibia fractures

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

@article{aced503d99f947f4b1c891db8aea4de1,
title = "A prospective randomized trial to assess fixation strategies for severe open tibia fractures: Modern ring external fixators versus internal fixation (FIXIT Study)",
abstract = "The treatment of high-energy open tibia fractures is challenging in both the military and civilian environments. Treatment with modern ring external fixation may reduce complications common in these patients. However, no study has rigorously compared outcomes of modern ring external fixation with commonly used internal fixation approaches. The FIXIT study is a prospective, multicenter randomized trial comparing 1-year outcomes after treatment of severe open tibial shaft fractures with modern external ring fixation versus internal fixation among men and women of ages 18-64. The primary outcome is rehospitalization for major limb complications. Secondary outcomes include infection, fracture healing, limb function, and patient-reported outcomes including physical function and pain. One-year treatment costs and patient satisfaction will be compared between the 2 groups, and the percentage of Gustilo IIIB fractures that can be salvaged without soft tissue flap among patients receiving external fixation will be estimated.",
keywords = "External ring fixation, Internal fixation, Open tibia fractures",
author = "METRC and O'Toole, {Robert V.} and Gary, {Joshua L.} and Lisa Reider and Bosse, {Michael J.} and Gordon, {Wade T.} and {Hutson, Jr.}, James and Stephen Quinnan and Castillo, {Renan C.} and Scharfstein, {Daniel O.} and MacKenzie, {Ellen J.} and Allen, {Lauren E.} and Ballreich, {Jeromie M.} and Carlini, {Anthony R.} and {De Lissovoy}, Gregory and Rachel Kirk and Jason Luly and Owens, {Christina D.}",
year = "2017",
doi = "10.1097/BOT.0000000000000804",
language = "English (US)",
volume = "31",
pages = "S10--S17",
journal = "Journal of Orthopaedic Trauma",
issn = "0890-5339",
publisher = "Lippincott Williams and Wilkins",

}

TY - JOUR

T1 - A prospective randomized trial to assess fixation strategies for severe open tibia fractures

T2 - Modern ring external fixators versus internal fixation (FIXIT Study)

AU - METRC

AU - O'Toole, Robert V.

AU - Gary, Joshua L.

AU - Reider, Lisa

AU - Bosse, Michael J.

AU - Gordon, Wade T.

AU - Hutson, Jr., James

AU - Quinnan, Stephen

AU - Castillo, Renan C.

AU - Scharfstein, Daniel O.

AU - MacKenzie, Ellen J.

AU - Allen, Lauren E.

AU - Ballreich, Jeromie M.

AU - Carlini, Anthony R.

AU - De Lissovoy, Gregory

AU - Kirk, Rachel

AU - Luly, Jason

AU - Owens, Christina D.

PY - 2017

Y1 - 2017

N2 - The treatment of high-energy open tibia fractures is challenging in both the military and civilian environments. Treatment with modern ring external fixation may reduce complications common in these patients. However, no study has rigorously compared outcomes of modern ring external fixation with commonly used internal fixation approaches. The FIXIT study is a prospective, multicenter randomized trial comparing 1-year outcomes after treatment of severe open tibial shaft fractures with modern external ring fixation versus internal fixation among men and women of ages 18-64. The primary outcome is rehospitalization for major limb complications. Secondary outcomes include infection, fracture healing, limb function, and patient-reported outcomes including physical function and pain. One-year treatment costs and patient satisfaction will be compared between the 2 groups, and the percentage of Gustilo IIIB fractures that can be salvaged without soft tissue flap among patients receiving external fixation will be estimated.

AB - The treatment of high-energy open tibia fractures is challenging in both the military and civilian environments. Treatment with modern ring external fixation may reduce complications common in these patients. However, no study has rigorously compared outcomes of modern ring external fixation with commonly used internal fixation approaches. The FIXIT study is a prospective, multicenter randomized trial comparing 1-year outcomes after treatment of severe open tibial shaft fractures with modern external ring fixation versus internal fixation among men and women of ages 18-64. The primary outcome is rehospitalization for major limb complications. Secondary outcomes include infection, fracture healing, limb function, and patient-reported outcomes including physical function and pain. One-year treatment costs and patient satisfaction will be compared between the 2 groups, and the percentage of Gustilo IIIB fractures that can be salvaged without soft tissue flap among patients receiving external fixation will be estimated.

KW - External ring fixation

KW - Internal fixation

KW - Open tibia fractures

UR - http://www.scopus.com/inward/record.url?scp=85017295410&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85017295410&partnerID=8YFLogxK

U2 - 10.1097/BOT.0000000000000804

DO - 10.1097/BOT.0000000000000804

M3 - Article

C2 - 28323796

AN - SCOPUS:85017295410

VL - 31

SP - S10-S17

JO - Journal of Orthopaedic Trauma

JF - Journal of Orthopaedic Trauma

SN - 0890-5339

ER -