A prospective, randomized trial of acticoat versus silver sulfadiazine in the treatment of partial-thickness burns: Which method is less painful?

Robin Prater Varas, Terence O'Keeffe, Nicholas Namias, Louis R. Pizano, Olga Delia Quintana, Marlene Herrero Tellachea, Qammar Rashid, C. Gillon Ward

Research output: Contribution to journalArticle

48 Scopus citations


Despite recent improvements in analgesia, pain control during dressing changes continues to be a major challenge in patients with burns. We investigated two different dressing modalities to compare how much pain the patient experienced during and after the dressing change. Patients with partial-thickness burns that required only topical wound care were assigned randomly to treatment with Acticoat® (Smith and Nephew USA, Largo, FL) or silver sulfadiazine (AgSD). The outcome variable was pain during wound care, which was measured using visual analog pain scores. The mean visual analog pain scores for the wounds treated with Acticoat® or AgSD wounds were 3.2 and 7.9, respectively (P < .0001; paired Student's t-test). In 41 of the 47 paired pain score observations, the pain in the wound treated with AgSD was perceived as greater than in the wound treated with Acticoat®. Burn wound care with Acticoat® is less painful than burn wound care with AgSD in patients with selected partial-thickness burns.

Original languageEnglish (US)
Pages (from-to)344-347
Number of pages4
JournalJournal of Burn Care and Rehabilitation
Issue number4
StatePublished - Jul 1 2005


ASJC Scopus subject areas

  • Surgery
  • Nursing(all)
  • Emergency Medicine
  • Rehabilitation
  • Health Professions(all)

Cite this