A placebo-controlled, double-blind comparison of clobazam and diazepam in the treatment of anxiety

A. F. Jacobson, B. J. Goldstein, R. A. Dominguez, R. M. Steinbook

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

In a randomized, placebo-controlled, double-blind study, the efficacy and safety of clobazam and diazepam were compared in 114 anxious outpatients. During the 4-week double-blind phase of the study, the mean daily dose was 59 mg for clobazam and 25 mg for diazepam. Results indicate statistically significant efficacy, measured by both patient and physician rating scales, for both active drugs compared to placebo. The incidence of sedation was similar for the two active treatment groups; dizziness was more frequent in the diazepam group.

Original languageEnglish (US)
Pages (from-to)296-300
Number of pages5
JournalJournal of Clinical Psychiatry
Volume44
Issue number8 I
StatePublished - Jan 1 1983

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ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Jacobson, A. F., Goldstein, B. J., Dominguez, R. A., & Steinbook, R. M. (1983). A placebo-controlled, double-blind comparison of clobazam and diazepam in the treatment of anxiety. Journal of Clinical Psychiatry, 44(8 I), 296-300.