Abstract
In a randomized, placebo-controlled, double-blind study, the efficacy and safety of clobazam and diazepam were compared in 114 anxious outpatients. During the 4-week double-blind phase of the study, the mean daily dose was 59 mg for clobazam and 25 mg for diazepam. Results indicate statistically significant efficacy, measured by both patient and physician rating scales, for both active drugs compared to placebo. The incidence of sedation was similar for the two active treatment groups; dizziness was more frequent in the diazepam group.
| Original language | English |
|---|---|
| Pages (from-to) | 296-300 |
| Number of pages | 5 |
| Journal | Journal of Clinical Psychiatry |
| Volume | 44 |
| Issue number | 8 I |
| State | Published - Jan 1 1983 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Psychiatry and Mental health
- Clinical Psychology
Cite this
A placebo-controlled, double-blind comparison of clobazam and diazepam in the treatment of anxiety. / Jacobson, A. F.; Goldstein, B. J.; Dominguez, R. A.; Steinbook, R. M.
In: Journal of Clinical Psychiatry, Vol. 44, No. 8 I, 01.01.1983, p. 296-300.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A placebo-controlled, double-blind comparison of clobazam and diazepam in the treatment of anxiety
AU - Jacobson, A. F.
AU - Goldstein, B. J.
AU - Dominguez, R. A.
AU - Steinbook, R. M.
PY - 1983/1/1
Y1 - 1983/1/1
N2 - In a randomized, placebo-controlled, double-blind study, the efficacy and safety of clobazam and diazepam were compared in 114 anxious outpatients. During the 4-week double-blind phase of the study, the mean daily dose was 59 mg for clobazam and 25 mg for diazepam. Results indicate statistically significant efficacy, measured by both patient and physician rating scales, for both active drugs compared to placebo. The incidence of sedation was similar for the two active treatment groups; dizziness was more frequent in the diazepam group.
AB - In a randomized, placebo-controlled, double-blind study, the efficacy and safety of clobazam and diazepam were compared in 114 anxious outpatients. During the 4-week double-blind phase of the study, the mean daily dose was 59 mg for clobazam and 25 mg for diazepam. Results indicate statistically significant efficacy, measured by both patient and physician rating scales, for both active drugs compared to placebo. The incidence of sedation was similar for the two active treatment groups; dizziness was more frequent in the diazepam group.
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UR - http://www.scopus.com/inward/citedby.url?scp=0020550527&partnerID=8YFLogxK
M3 - Article
C2 - 6135690
AN - SCOPUS:0020550527
VL - 44
SP - 296
EP - 300
JO - Journal of Clinical Psychiatry
JF - Journal of Clinical Psychiatry
SN - 0160-6689
IS - 8 I
ER -