A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa

Lena S. Andersen; Jessica F. Magidson; Conall O’Cleirigh; Jessica E. Remmert; Ashraf Kagee; Matthew Leaver; Dan J. Stein; Steven A. Safren; John Joska

doi:10.1177/1359105316643375

A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa

Lena S. Andersen, Jessica F. Magidson, Conall O’Cleirigh, Jessica E. Remmert, Ashraf Kagee, Matthew Leaver, Dan J. Stein, Steven A. Safren, John Joska

Psychology

Research output: Contribution to journal › Article

18 Scopus citations

Abstract

Depression is prevalent among people living with HIV in South Africa and interferes with adherence to antiretroviral therapy. This study evaluated a nurse-delivered, cognitive behavioral therapy intervention for adherence and depression among antiretroviral therapy users with depression in South Africa (n = 14). Primary outcomes were depression, antiretroviral therapy adherence, feasibility, and acceptability. Findings support robust improvements in mood through a 3-month follow up. Antiretroviral therapy adherence was maintained during the intervention period. Participant retention supports acceptability; however, modest provider fidelity despite intensive supervision warrants additional attention to feasibility. Future effectiveness research is needed to evaluate this nurse-delivered cognitive behavioral therapy intervention for adherence and depression in this context.

Original language	English (US)
Pages (from-to)	776-787
Number of pages	12
Journal	Journal of Health Psychology
Volume	23
Issue number	6
DOIs	https://doi.org/10.1177/1359105316643375
State	Published - May 1 2018

Keywords

HIV
South Africa
adherence
cognitive behavioral therapy
depression
low- and middle-income countries
task-sharing

ASJC Scopus subject areas

Applied Psychology

Access to Document

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Andersen, L. S., Magidson, J. F., O’Cleirigh, C., Remmert, J. E., Kagee, A., Leaver, M., Stein, D. J., Safren, S. A., & Joska, J. (2018). A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa. Journal of Health Psychology, 23(6), 776-787. https://doi.org/10.1177/1359105316643375

A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa. / Andersen, Lena S.; Magidson, Jessica F.; O’Cleirigh, Conall; Remmert, Jessica E.; Kagee, Ashraf; Leaver, Matthew; Stein, Dan J.; Safren, Steven A.; Joska, John.

In: Journal of Health Psychology, Vol. 23, No. 6, 01.05.2018, p. 776-787.

Research output: Contribution to journal › Article

Andersen, Lena S. ; Magidson, Jessica F. ; O’Cleirigh, Conall ; Remmert, Jessica E. ; Kagee, Ashraf ; Leaver, Matthew ; Stein, Dan J. ; Safren, Steven A. ; Joska, John. / A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa. In: Journal of Health Psychology. 2018 ; Vol. 23, No. 6. pp. 776-787.

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