A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa

Lena S. Andersen, Jessica F. Magidson, Conall O’Cleirigh, Jessica E. Remmert, Ashraf Kagee, Matthew Leaver, Dan J. Stein, Steven Safren, John Joska

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Depression is prevalent among people living with HIV in South Africa and interferes with adherence to antiretroviral therapy. This study evaluated a nurse-delivered, cognitive behavioral therapy intervention for adherence and depression among antiretroviral therapy users with depression in South Africa (n = 14). Primary outcomes were depression, antiretroviral therapy adherence, feasibility, and acceptability. Findings support robust improvements in mood through a 3-month follow up. Antiretroviral therapy adherence was maintained during the intervention period. Participant retention supports acceptability; however, modest provider fidelity despite intensive supervision warrants additional attention to feasibility. Future effectiveness research is needed to evaluate this nurse-delivered cognitive behavioral therapy intervention for adherence and depression in this context.

Original languageEnglish (US)
Pages (from-to)776-787
Number of pages12
JournalJournal of Health Psychology
Volume23
Issue number6
DOIs
StatePublished - May 1 2018

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Cognitive Therapy
South Africa
Nurses
HIV
Depression
Therapeutics
Research

Keywords

  • adherence
  • cognitive behavioral therapy
  • depression
  • HIV
  • low- and middle-income countries
  • South Africa
  • task-sharing

ASJC Scopus subject areas

  • Applied Psychology

Cite this

A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa. / Andersen, Lena S.; Magidson, Jessica F.; O’Cleirigh, Conall; Remmert, Jessica E.; Kagee, Ashraf; Leaver, Matthew; Stein, Dan J.; Safren, Steven; Joska, John.

In: Journal of Health Psychology, Vol. 23, No. 6, 01.05.2018, p. 776-787.

Research output: Contribution to journalArticle

Andersen, Lena S. ; Magidson, Jessica F. ; O’Cleirigh, Conall ; Remmert, Jessica E. ; Kagee, Ashraf ; Leaver, Matthew ; Stein, Dan J. ; Safren, Steven ; Joska, John. / A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa. In: Journal of Health Psychology. 2018 ; Vol. 23, No. 6. pp. 776-787.
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