A Personalized approach to managing inflammatory bowel disease

Michael J. Kingsley, Maria T Abreu

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

The management of inflammatory bowel disease (IBD) requires a personalized approach to treat what is a heterogeneous group of patients with inherently variable disease courses. In its current state, personalized care of the IBD patient involves identifying patients at high risk for rapid progression to complications, selecting the most appropriate therapy for a given patient, using therapeutic drug monitoring, and achieving the individualized goal that is most appropriate for that patient. The growing body of research in this area allows clinicians to better predict outcomes for individual patients. Some paradigms, especially within the realm of therapeutic drug monitoring, have begun to change as therapy is targeted to individual patient results and goals. Future personalized medical decisions may allow specific therapeutic plans to draw on serologic, genetic, and microbial data for Crohn's disease and ulcerative colitis patients.

Original languageEnglish (US)
Pages (from-to)308-315
Number of pages8
JournalGastroenterology and Hepatology
Volume12
Issue number5
StatePublished - May 1 2016

Keywords

  • Biomarkers
  • Crohn's disease
  • Inflammatory bowel disease
  • Personalized medicine
  • Serologic markers
  • Therapeutic drug monitoring
  • Ulcerative colitis

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

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