A novel isoform of Cbl-associated protein that binds protein kinase A

Sarah A. Matson; Genevieve C. Pare; Michael S. Kapiloff

doi:10.1016/j.bbaexp.2004.12.004

A novel isoform of Cbl-associated protein that binds protein kinase A

Sarah A. Matson, Genevieve C. Pare, Michael S. Kapiloff

Pediatrics

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

A novel isoform of Cbl-associated protein (CAP) was identified in a yeast two-hybrid screen for A-kinase anchoring proteins expressed in the heart. CAP is a scaffold protein implicated in insulin signaling and cytoskeleton regulation. The protein kinase A binding site is encoded by a previously unidentified, alternatively spliced exon.

Original language	English (US)
Pages (from-to)	145-149
Number of pages	5
Journal	Biochimica et Biophysica Acta - Gene Structure and Expression
Volume	1727
Issue number	2
DOIs	https://doi.org/10.1016/j.bbaexp.2004.12.004
State	Published - Feb 14 2005

Keywords

A-kinase anchoring protein
Cbl-associated protein
Heart
Protein kinase A
SORBS1

ASJC Scopus subject areas

Biochemistry
Genetics
Structural Biology
Biophysics

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title = "A novel isoform of Cbl-associated protein that binds protein kinase A",

abstract = "A novel isoform of Cbl-associated protein (CAP) was identified in a yeast two-hybrid screen for A-kinase anchoring proteins expressed in the heart. CAP is a scaffold protein implicated in insulin signaling and cytoskeleton regulation. The protein kinase A binding site is encoded by a previously unidentified, alternatively spliced exon.",

keywords = "A-kinase anchoring protein, Cbl-associated protein, Heart, Protein kinase A, SORBS1",

author = "Matson, {Sarah A.} and Pare, {Genevieve C.} and Kapiloff, {Michael S.}",

note = "Funding Information: This work was supported by NHLBI grants K08 HL04229 and R01 HL075398. We thank John Scott and Neal Alto for the RIIα yeast two-hybrid bait vector.",

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doi = "10.1016/j.bbaexp.2004.12.004",

language = "English (US)",

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T1 - A novel isoform of Cbl-associated protein that binds protein kinase A

AU - Matson, Sarah A.

AU - Pare, Genevieve C.

AU - Kapiloff, Michael S.

N1 - Funding Information: This work was supported by NHLBI grants K08 HL04229 and R01 HL075398. We thank John Scott and Neal Alto for the RIIα yeast two-hybrid bait vector.

PY - 2005/2/14

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AB - A novel isoform of Cbl-associated protein (CAP) was identified in a yeast two-hybrid screen for A-kinase anchoring proteins expressed in the heart. CAP is a scaffold protein implicated in insulin signaling and cytoskeleton regulation. The protein kinase A binding site is encoded by a previously unidentified, alternatively spliced exon.

KW - A-kinase anchoring protein

KW - Cbl-associated protein

KW - Heart

KW - Protein kinase A

KW - SORBS1

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SP - 145

EP - 149

JO - Biochimica et Biophysica Acta - Gene Structure and Expression

JF - Biochimica et Biophysica Acta - Gene Structure and Expression

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