A novel characterization of posterior keratoconus using anterior segment optical coherence tomography in an infant: A case report Cornea and external eye diseases

Nisha Garg, Ta Chang, Bibiana Jin Reiser, Kara M Cavuoto

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2 Scopus citations


Background: Posterior keratoconus is a rare cause of a corneal opacity in an infant. It is characterized by thinning of the posterior cornea without ectasia of the anterior cornea. Imaging of this condition with anterior segment optical coherence tomography (AS-OCT) has not been reported in the literature. Case presentation: A six week old African-American male presented with a congenital corneal opacity of the right eye. He underwent an examination under anesthesia in which photography and AS-OCT were performed. AS-OCT confirmed the diagnosis of posterior keratoconus. The patient subsequently underwent an optical iridectomy for visual development. Conclusion: AS-OCT is a useful tool in cases when a child presents with a corneal opacity of unknown or unclear etiology. In our patient, AS-OCT showed the classic description of central corneal thinning seen in this condition. Additionally, it revealed an associated detached Descemet membrane, a feature which has not been previously described in posterior keratoconus.

Original languageEnglish (US)
Article number158
JournalBMC Ophthalmology
Issue number1
StatePublished - Nov 4 2015



  • Anterior segment optical coherence tomography
  • Corneal opacity
  • Infant
  • Posterior keratoconus

ASJC Scopus subject areas

  • Ophthalmology

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