A novel bonding method for polymer-based microfluidic platforms

Siyi Lai, Yeny Hudiono, L. James Lee, Sylvia Daunert, Marc J. Madou

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

Polymer-based microfluidic platforms have great potential for use in BioMEMS applications because many polymers are low cost, biocompatible, and have good processibility. However, packaging (i.e., sealing the platform with a lid) is a challenging issue in their fabrication. In this paper, we compare several available bonding techniques such as adhesive tape bonding and chemical-assisted bonding with a new method recently developed in our lab: resin-gas injection-assisted bonding. This new approach can easily seal microfluidic devices with micron and sub-micron sized channels without blocking the flow path. It can also be used to modify the channel shape, size, and surface characteristics (e.g., hydrophilicity, degree of protein adsorption). By applying the masking technique, local modification of the channel surface can be achieved through cascade resin-gas injection. Experiments are carded out to demonstrate the bonding efficiency and surface modification.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsJ.M. Karam, J Yasaitis
Pages280-287
Number of pages8
Volume4557
DOIs
StatePublished - 2001
Externally publishedYes
EventMicromachining and Microfabrication Process Technology VII - San Francisco, CA, United States
Duration: Oct 22 2001Oct 24 2001

Other

OtherMicromachining and Microfabrication Process Technology VII
CountryUnited States
CitySan Francisco, CA
Period10/22/0110/24/01

Fingerprint

Microfluidics
platforms
polymers
Polymers
gas injection
resins
BioMEMS
Resins
microfluidic devices
sealing
Hydrophilicity
masking
packaging
Tapes
adhesives
tapes
Seals
Surface treatment
Adhesives
Packaging

Keywords

  • Bonding
  • Microfluidic
  • Surface modification

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Lai, S., Hudiono, Y., Lee, L. J., Daunert, S., & Madou, M. J. (2001). A novel bonding method for polymer-based microfluidic platforms. In J. M. Karam, & J. Yasaitis (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 4557, pp. 280-287) https://doi.org/10.1117/12.442956

A novel bonding method for polymer-based microfluidic platforms. / Lai, Siyi; Hudiono, Yeny; Lee, L. James; Daunert, Sylvia; Madou, Marc J.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / J.M. Karam; J Yasaitis. Vol. 4557 2001. p. 280-287.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lai, S, Hudiono, Y, Lee, LJ, Daunert, S & Madou, MJ 2001, A novel bonding method for polymer-based microfluidic platforms. in JM Karam & J Yasaitis (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 4557, pp. 280-287, Micromachining and Microfabrication Process Technology VII, San Francisco, CA, United States, 10/22/01. https://doi.org/10.1117/12.442956
Lai S, Hudiono Y, Lee LJ, Daunert S, Madou MJ. A novel bonding method for polymer-based microfluidic platforms. In Karam JM, Yasaitis J, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 4557. 2001. p. 280-287 https://doi.org/10.1117/12.442956
Lai, Siyi ; Hudiono, Yeny ; Lee, L. James ; Daunert, Sylvia ; Madou, Marc J. / A novel bonding method for polymer-based microfluidic platforms. Proceedings of SPIE - The International Society for Optical Engineering. editor / J.M. Karam ; J Yasaitis. Vol. 4557 2001. pp. 280-287
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