A new type D retrovirus isolated from macaques with an immunodeficiency syndrome

Muthiah D. Daniel, Norval W. King, Norman L. Letvin, Ronald D. Hunt, Prabhat K. Sehgal, Ronald C. Desrosiers

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152 Scopus citations

Abstract

Macaque monkeys with the recently described acquired immunodeficiency syndrome show a marked defect in T-lymphocyte function and die with opportunistic infections and lymphoproliferative abnormalities. In the study described here a new type D retrovirus was isolatedfrom two Macaca cyclopis with this syndrome. This virus is related to, but distinct from, Mason-Pfizer monkey virus, a type D retrovirus previously isolated from a mammary tumor of a rhesus monkey (Macaca mulatta).

Original languageEnglish (US)
Pages (from-to)602-605
Number of pages4
JournalScience
Volume223
Issue number4636
DOIs
StatePublished - Jan 1 1984
Externally publishedYes

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    Daniel, M. D., King, N. W., Letvin, N. L., Hunt, R. D., Sehgal, P. K., & Desrosiers, R. C. (1984). A new type D retrovirus isolated from macaques with an immunodeficiency syndrome. Science, 223(4636), 602-605. https://doi.org/10.1126/science.6695172