A new type D retrovirus isolated from macaques with an immunodeficiency syndrome

Muthiah D. Daniel, Norval W. King, Norman L. Letvin, Ronald D. Hunt, Prabhat K. Sehgal, Ronald C. Desrosiers

Research output: Contribution to journalArticlepeer-review

152 Scopus citations

Abstract

Macaque monkeys with the recently described acquired immunodeficiency syndrome show a marked defect in T-lymphocyte function and die with opportunistic infections and lymphoproliferative abnormalities. In the study described here a new type D retrovirus was isolatedfrom two Macaca cyclopis with this syndrome. This virus is related to, but distinct from, Mason-Pfizer monkey virus, a type D retrovirus previously isolated from a mammary tumor of a rhesus monkey (Macaca mulatta).

Original languageEnglish (US)
Pages (from-to)602-605
Number of pages4
JournalScience
Volume223
Issue number4636
DOIs
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • General

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