A new type D retrovirus isolated from macaques with an immunodeficiency syndrome

M. D. Daniel, N. W. King, N. L. Letvin, R. D. Hunt, P. K. Sehgal, Ronald Charles Desrosiers

Research output: Contribution to journalArticle

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Abstract

Macaque monkeys with the recently described acquired immunodeficiency syndrome show a marked defect in T-lymphocyte function and die with opportunistic infections and lymphoproliferative abnormalities. In the study described here a new type D retrovirus was isolated from two Macaca cyclopis with this syndrome. This virus is related to, but distinct from, Mason-Pfizer monkey virus, a type D retrovirus previously isolated from a mammary tumor of a rhesus monkey (Macaca mulatta).

Original languageEnglish (US)
Pages (from-to)602-605
Number of pages4
JournalScience
Volume223
Issue number4636
DOIs
StatePublished - 1984
Externally publishedYes

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Betaretrovirus
Macaca
Macaca mulatta
Mason-Pfizer monkey virus
Opportunistic Infections
Haplorhini
Acquired Immunodeficiency Syndrome
Breast Neoplasms
Viruses
T-Lymphocytes

ASJC Scopus subject areas

  • General

Cite this

Daniel, M. D., King, N. W., Letvin, N. L., Hunt, R. D., Sehgal, P. K., & Desrosiers, R. C. (1984). A new type D retrovirus isolated from macaques with an immunodeficiency syndrome. Science, 223(4636), 602-605. https://doi.org/10.1126/science.6695172

A new type D retrovirus isolated from macaques with an immunodeficiency syndrome. / Daniel, M. D.; King, N. W.; Letvin, N. L.; Hunt, R. D.; Sehgal, P. K.; Desrosiers, Ronald Charles.

In: Science, Vol. 223, No. 4636, 1984, p. 602-605.

Research output: Contribution to journalArticle

Daniel, MD, King, NW, Letvin, NL, Hunt, RD, Sehgal, PK & Desrosiers, RC 1984, 'A new type D retrovirus isolated from macaques with an immunodeficiency syndrome', Science, vol. 223, no. 4636, pp. 602-605. https://doi.org/10.1126/science.6695172
Daniel, M. D. ; King, N. W. ; Letvin, N. L. ; Hunt, R. D. ; Sehgal, P. K. ; Desrosiers, Ronald Charles. / A new type D retrovirus isolated from macaques with an immunodeficiency syndrome. In: Science. 1984 ; Vol. 223, No. 4636. pp. 602-605.
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