Postoperative complications of transcorneal fixated keratoprosthesis (KPro) are frequent and severe and may lead to the loss of the eye. To avoid these problems, a novel supra-Descemetic, non penetrating mesoplant was developed. It is locked in place by an annular skirt and is placed over Descemet's membrane. Four different biocompatible polymers were implanted in eyes of New Zealand white rabbits (NZW). A new delamination and trephination technique was developed. In 8 eyes the new KPro (2× PMMA, 2× Hema-NVP, 2× Hema-MMA and 2× Hema-EMA) were implanted. There were no postoperative complications, the KPros stayed clear and in place and allowed an excellent view of the fundus. The follow-up of one month is nevertheless too short to determine stability and possible use of this new KPro in humans.
- Descemet membrane
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