A new model system for studying the phosphatidylinositol cycle

Marie E. Monaco; Marc E. Lippman

doi:10.1002/jcp.1041120122

A new model system for studying the phosphatidylinositol cycle

Marie E. Monaco, Marc E. Lippman

Medicine

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

An early manifestation of the response of WRK-1 rat mammary tumor cells to vasopressin is an increase in incorporation of (³²P)Pi into phospholipids. Incorporation into all classes of phospholipids is stimulated; however, incorporation into phosphatidylinositol (Pl) is increased to the greatest degree (3- to 10-fold as compared with 1.3- to 2-fold for the other phospholipids). Furthermore, increased incorporation into Pl is accompanied by an increased rate of Pl turnover; turnover rates of the other phospholipids are unaffected by vasopressin.

Original language	English (US)
Pages (from-to)	148-153
Number of pages	6
Journal	Journal of Cellular Physiology
Volume	112
Issue number	1
DOIs	https://doi.org/10.1002/jcp.1041120122
State	Published - Jul 1982

ASJC Scopus subject areas

Physiology
Clinical Biochemistry
Cell Biology

Access to Document

10.1002/jcp.1041120122

Fingerprint Dive into the research topics of 'A new model system for studying the phosphatidylinositol cycle'. Together they form a unique fingerprint.

Cite this

@article{b45c793c9134433980d649f3a5a056e7,

title = "A new model system for studying the phosphatidylinositol cycle",

abstract = "An early manifestation of the response of WRK-1 rat mammary tumor cells to vasopressin is an increase in incorporation of (32P)Pi into phospholipids. Incorporation into all classes of phospholipids is stimulated; however, incorporation into phosphatidylinositol (Pl) is increased to the greatest degree (3- to 10-fold as compared with 1.3- to 2-fold for the other phospholipids). Furthermore, increased incorporation into Pl is accompanied by an increased rate of Pl turnover; turnover rates of the other phospholipids are unaffected by vasopressin.",

author = "Monaco, {Marie E.} and Lippman, {Marc E.}",

year = "1982",

month = jul,

doi = "10.1002/jcp.1041120122",

language = "English (US)",

volume = "112",

pages = "148--153",

journal = "Journal of Cellular Physiology",

issn = "0021-9541",

publisher = "Wiley-Liss Inc.",

number = "1",

}

TY - JOUR

T1 - A new model system for studying the phosphatidylinositol cycle

AU - Monaco, Marie E.

AU - Lippman, Marc E.

PY - 1982/7

Y1 - 1982/7

N2 - An early manifestation of the response of WRK-1 rat mammary tumor cells to vasopressin is an increase in incorporation of (32P)Pi into phospholipids. Incorporation into all classes of phospholipids is stimulated; however, incorporation into phosphatidylinositol (Pl) is increased to the greatest degree (3- to 10-fold as compared with 1.3- to 2-fold for the other phospholipids). Furthermore, increased incorporation into Pl is accompanied by an increased rate of Pl turnover; turnover rates of the other phospholipids are unaffected by vasopressin.

AB - An early manifestation of the response of WRK-1 rat mammary tumor cells to vasopressin is an increase in incorporation of (32P)Pi into phospholipids. Incorporation into all classes of phospholipids is stimulated; however, incorporation into phosphatidylinositol (Pl) is increased to the greatest degree (3- to 10-fold as compared with 1.3- to 2-fold for the other phospholipids). Furthermore, increased incorporation into Pl is accompanied by an increased rate of Pl turnover; turnover rates of the other phospholipids are unaffected by vasopressin.

UR - http://www.scopus.com/inward/record.url?scp=0019953601&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019953601&partnerID=8YFLogxK

U2 - 10.1002/jcp.1041120122

DO - 10.1002/jcp.1041120122

M3 - Article

C2 - 7050132

AN - SCOPUS:0019953601

VL - 112

SP - 148

EP - 153

JO - Journal of Cellular Physiology

JF - Journal of Cellular Physiology

SN - 0021-9541

IS - 1

ER -