A method for in vivo high resolution MRI of rat spinal cord injury

John C. Ford, David B. Hackney, Peter M. Joseph, Megan Phelan, David C. Alsop, Stacy L. Tabor, Christopher M. Hand, Ronald S. Markowitz, Perry Black

Research output: Contribution to journalArticle

50 Scopus citations

Abstract

We have developed an implanted radiofrequency coil to obtain high resolution in vivo MR images at 1.9 Tesla of rat spinal cords that have been injured using a standardized weight drop technique. The signal‐to‐noise ratio and motion artifact suppression of these images is superior to that achieved in earlier attempts at this field strength using an external surface coil. The high quality and spatial resolution provided by this technique afford the possibility for longitudinal studies of experimental spinal cord injury before and after treatment, as well as detailed correlation of in vivo MRI contrast, histopathological findings, and functional deficit, in a controlled setting.

Original languageEnglish (US)
Pages (from-to)218-223
Number of pages6
JournalMagnetic Resonance in Medicine
Volume31
Issue number2
DOIs
StatePublished - Feb 1994

Keywords

  • high resolution MRI
  • radiofrequency coils
  • spinal cord injury

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'A method for in vivo high resolution MRI of rat spinal cord injury'. Together they form a unique fingerprint.

  • Cite this

    Ford, J. C., Hackney, D. B., Joseph, P. M., Phelan, M., Alsop, D. C., Tabor, S. L., Hand, C. M., Markowitz, R. S., & Black, P. (1994). A method for in vivo high resolution MRI of rat spinal cord injury. Magnetic Resonance in Medicine, 31(2), 218-223. https://doi.org/10.1002/mrm.1910310216