A Mediterranean Diet in Relation to Subclinical Vascular Conditions

Hannah Gardener, Clinton B. Wright

Research output: Chapter in Book/Report/Conference proceedingChapter


Adherence to a Mediterranean-style diet may be associated with the risk of vascular outcomes including stroke, cardiac disease, and cognitive impairment through its effects on blood vessels and related vascular damage. White matter lesions, brain infarction, and arterio/atherosclerosis are often subclinical. This chapter reviews the current evidence for a relationship between a Mediterranean diet and these subclinical vascular conditions. While some studies support a potential role of adherence to a Mediterranean diet in decreasing the burden of these subclinical vascular conditions, limited research has been conducted; therefore, the findings are scant and inconclusive. More research is needed on whether such vascular damage lies on causal pathways linking a Mediterranean diet with clinical vascular events in order to help identify patients who may benefit most from dietary changes and to support the use of these common subclinical markers in future clinical trials examining dietary interventions for improving brain health.

Original languageEnglish (US)
Title of host publicationThe Mediterranean Diet
Subtitle of host publicationAn Evidence-Based Approach
PublisherElsevier Inc.
Number of pages12
ISBN (Electronic)9780124079427
ISBN (Print)9780124078499
StatePublished - 2015
Externally publishedYes


  • Atherosclerosis
  • Carotid artery
  • Mediterranean diet
  • Subclinical brain infarctions
  • Subclinical vascular outcomes
  • White matter hyperintensities

ASJC Scopus subject areas

  • Medicine(all)


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