A helicase is born

Carlos T Moraes

doi:10.1038/90020

A helicase is born

Carlos T Moraes

Neurology

Research output: Contribution to journal › Article

8 Citations (Scopus)

Abstract

One of three loci previously associated with autosomal dominant progressive external ophthalmoplegia (adPEO) encodes ANT1, a mitochondrial nucleotide transporter. Now, mutations in two other genes are found in people with adPEO. One of these encodes a new helicase, Twinkle, which is related to the product of bacteriophage T7 gene 4, and co-localizes with mitochondrial DNA. The identification of Twinkle adds a new star to the expanding constellation of 'helicase diseases'.

Original language	English
Pages (from-to)	200-201
Number of pages	2
Journal	Nature Genetics
Volume	28
Issue number	3
DOIs	https://doi.org/10.1038/90020
State	Published - Jul 20 2001

Fingerprint

Chronic Progressive External Ophthalmoplegia

Bacteriophage T7

Mitochondrial DNA

Genes

Nucleotides

Mutation

ASJC Scopus subject areas

Genetics(clinical)
Genetics

Cite this

Moraes, C. T. (2001). A helicase is born. Nature Genetics, 28(3), 200-201. https://doi.org/10.1038/90020

A helicase is born. / Moraes, Carlos T.

In: Nature Genetics, Vol. 28, No. 3, 20.07.2001, p. 200-201.

Research output: Contribution to journal › Article

Moraes, CT 2001, 'A helicase is born', Nature Genetics, vol. 28, no. 3, pp. 200-201. https://doi.org/10.1038/90020

Moraes CT. A helicase is born. Nature Genetics. 2001 Jul 20;28(3):200-201. https://doi.org/10.1038/90020

Moraes, Carlos T. / A helicase is born. In: Nature Genetics. 2001 ; Vol. 28, No. 3. pp. 200-201.

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Access to Document

10.1038/90020