A Family History Study of Neuropsychiatric Disorders in the Adult Siblings of Autistic Individuals

JOSEPH PIVEN, JEANNE GAYLE, GARY A. CHASE, BARBIE FINK, REBECCA LANDA, MARYANN M. WZOREK, SUSAN E. FOLSTEIN

Research output: Contribution to journalArticle

152 Scopus citations

Abstract

The family history method was used to obtain developmental, social, and psychiatric histories on the 67 adult siblings of 37 autistic probands. Two of 67 siblings (3.0%) were autistic, three siblings (4.4%) had severe social dysfunction and isolation, 10 (15%) had cognitive disorders, and 10 (15%) had received treatment for affective disorder. This study is the first to investigate the frequecy of disorders in the adult siblings of autistic probands. These results suggest aggregation of a variety of neuropsychiatric disorders in the siblings of autistic individuals.

Original languageEnglish (US)
Pages (from-to)177-183
Number of pages7
JournalJournal of the American Academy of Child and Adolescent Psychiatry
Volume29
Issue number2
DOIs
StatePublished - 1990

Keywords

  • affective disorder
  • autism
  • cognitive disorder
  • genetics

ASJC Scopus subject areas

  • Developmental and Educational Psychology
  • Psychiatry and Mental health

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    PIVEN, JOSEPH., GAYLE, JEANNE., CHASE, GARY. A., FINK, BARBIE., LANDA, REBECCA., WZOREK, MARYANN. M., & FOLSTEIN, SUSAN. E. (1990). A Family History Study of Neuropsychiatric Disorders in the Adult Siblings of Autistic Individuals. Journal of the American Academy of Child and Adolescent Psychiatry, 29(2), 177-183. https://doi.org/10.1097/00004583-199003000-00004