Abstract
To determine the efficacy of nedocromil sodium in adult asthma patients using bronchodilators alone to control their disease, a consecutive sample of 127 patients with long-term asthma was studied for 16 weeks. The patients were maintained on sustained release theophylline preparations (SRT) and inhaled and oral beta-adrenergic bronchodilators (β2). One hundred sixteen patients (90 percent) completed the study; one placebo-treated patient withdrew owing to throat irradiation and wheezing. Nedocromil sodium provided an additional benefit to adult patients receiving SRT and inhaled β2-agonists. With the exception of night-time asthma, nedocromil sodium maintained this improvement for the final 12 weeks of the study despite a reduction in concomitant bronchodilator therapy.
Original language | English (US) |
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Pages (from-to) | 1299-1306 |
Number of pages | 8 |
Journal | CHEST |
Volume | 97 |
Issue number | 6 |
DOIs | |
State | Published - Jan 1 1990 |
Externally published | Yes |
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
- Critical Care and Intensive Care Medicine
- Cardiology and Cardiovascular Medicine