A comparison of vascular pulsatility and resistive indices in gynecological tumor detection using transvaginal ultrasound

J. R. Carter, M. Lau, L. B. Twiggs

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Abstract

Transvaginal Doppler ultrasound was applied to 85 patients to determine whether pelvic malignancy could be predicted by pulsatility (PI) and resistive indices (RI) of intratumoral, ovarian, and uterine vessels. Thirty- five of the patients in the study were confirmed to have malignant tumors of the cervix, uterus, or ovary. The mean intratumoral PI and RI from malignant tumors were 0.81 (SD 0.24; range 0.3-1.2) and 0.54 (SD 0.10; range 0.27- 0.62), respectively. They were significantly lower than those of the benign group (both with P < 0.05, Student's t test). Thresholds of intratumoral PI < 1.0 and RI < 0.6, which differentiate malignant from benign tumors, were determined by using two receiver operating characteristic (ROC) curves. These gave a sensitivity of 94% and specificity of 63% for PI and a sensitivity of 71% and specificity of 63% for RI. The mean PI and RI from individual ovarian and uterine vessels were also significantly lower for the malignant group than those for the benign group. The authors conclude that PIs and RIs from intratumoral, ovarian, and uterine vessels are all useful in differentiating malignant tumors from benign ones, but universal thresholds for this purpose are far from determined. Also, comparison of intratumoral PI and RI showed that neither PI nor RI was statistically better than the other in malignancy prediction, because the areas under the two ROC curves were not statistically different (P > 0.2, chi-square method).

Original languageEnglish
Pages (from-to)29-35
Number of pages7
JournalVascular Surgery
Volume29
Issue number1
StatePublished - Jan 1 1995
Externally publishedYes

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Blood Vessels
Doppler Ultrasonography
Neoplasms
Cervix Uteri
Ovary

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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A comparison of vascular pulsatility and resistive indices in gynecological tumor detection using transvaginal ultrasound. / Carter, J. R.; Lau, M.; Twiggs, L. B.

In: Vascular Surgery, Vol. 29, No. 1, 01.01.1995, p. 29-35.

Research output: Contribution to journalArticle

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abstract = "Transvaginal Doppler ultrasound was applied to 85 patients to determine whether pelvic malignancy could be predicted by pulsatility (PI) and resistive indices (RI) of intratumoral, ovarian, and uterine vessels. Thirty- five of the patients in the study were confirmed to have malignant tumors of the cervix, uterus, or ovary. The mean intratumoral PI and RI from malignant tumors were 0.81 (SD 0.24; range 0.3-1.2) and 0.54 (SD 0.10; range 0.27- 0.62), respectively. They were significantly lower than those of the benign group (both with P < 0.05, Student's t test). Thresholds of intratumoral PI < 1.0 and RI < 0.6, which differentiate malignant from benign tumors, were determined by using two receiver operating characteristic (ROC) curves. These gave a sensitivity of 94{\%} and specificity of 63{\%} for PI and a sensitivity of 71{\%} and specificity of 63{\%} for RI. The mean PI and RI from individual ovarian and uterine vessels were also significantly lower for the malignant group than those for the benign group. The authors conclude that PIs and RIs from intratumoral, ovarian, and uterine vessels are all useful in differentiating malignant tumors from benign ones, but universal thresholds for this purpose are far from determined. Also, comparison of intratumoral PI and RI showed that neither PI nor RI was statistically better than the other in malignancy prediction, because the areas under the two ROC curves were not statistically different (P > 0.2, chi-square method).",
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