A case report of simultaneous thrombosis of two coronary artery stents in association with clopidogrel resistance

Sun Lee Jin, Steven P. Dunn, Helen M. Marshall, Mauricio G Cohen, Susan S. Smyth

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Despite aggressive antiplatelet therapy in the setting of PCI, the incidence of acute stent thrombosis remains approximately 0.5-2%. We report a patient with simultaneous thrombosis of two drug-eluting coronary artery stents, suggesting a systemic thrombotic state. Evaluation by optical platelet aggregometry revealed clopidogrel resistance, which was overcome at a higher drug dose. We aim to highlight the potential utility of platelet function analysis to guide therapy for patients in whom inadequate antiplatelet therapy may have catastrophic clinical outcomes.

Original languageEnglish
Pages (from-to)200-203
Number of pages4
JournalClinical Cardiology
Volume30
Issue number4
DOIs
StatePublished - Apr 1 2007
Externally publishedYes

Fingerprint

clopidogrel
Stents
Coronary Vessels
Thrombosis
Blood Platelets
Pharmaceutical Preparations
Therapeutics
Incidence

Keywords

  • Angiography
  • Platelet
  • Stent
  • Thrombosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

A case report of simultaneous thrombosis of two coronary artery stents in association with clopidogrel resistance. / Jin, Sun Lee; Dunn, Steven P.; Marshall, Helen M.; Cohen, Mauricio G; Smyth, Susan S.

In: Clinical Cardiology, Vol. 30, No. 4, 01.04.2007, p. 200-203.

Research output: Contribution to journalArticle

Jin, Sun Lee ; Dunn, Steven P. ; Marshall, Helen M. ; Cohen, Mauricio G ; Smyth, Susan S. / A case report of simultaneous thrombosis of two coronary artery stents in association with clopidogrel resistance. In: Clinical Cardiology. 2007 ; Vol. 30, No. 4. pp. 200-203.
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