A Case of Weber-Christian Disease With Collapsing Glomerulopathy

Nilay Nahar, Victoriano Pardo, Sanghamitra Sadhu, Larry Young, Nora Gonzalez, Edgar A. Jaimes

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

We report a case of Weber-Christian disease confirmed by skin biopsy in a patient who presented with collapsing glomerulopathy and lipophagic interstitial nephritis. On renal biopsy, glomerular visceral epithelial cells, tubular cells, and interstitial macrophages were loaded with inclusions that were morphologically consistent with oxidized lipoproteins, suggesting that lipids derived from the panniculitis may have an etiopathogenic role.

Original languageEnglish (US)
Pages (from-to)484-488
Number of pages5
JournalAmerican Journal of Kidney Diseases
Volume48
Issue number3
DOIs
StatePublished - Sep 1 2006
Externally publishedYes

Keywords

  • collapsing glomerulopathy
  • panniculitis
  • proteinuria
  • Weber-Christian disease

ASJC Scopus subject areas

  • Nephrology

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