A Case of Weber-Christian Disease With Collapsing Glomerulopathy

Nilay Nahar, Victoriano Pardo, Sanghamitra Sadhu, Larry Young, Nora Gonzalez, Edgar A. Jaimes

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We report a case of Weber-Christian disease confirmed by skin biopsy in a patient who presented with collapsing glomerulopathy and lipophagic interstitial nephritis. On renal biopsy, glomerular visceral epithelial cells, tubular cells, and interstitial macrophages were loaded with inclusions that were morphologically consistent with oxidized lipoproteins, suggesting that lipids derived from the panniculitis may have an etiopathogenic role.

Original languageEnglish
Pages (from-to)484-488
Number of pages5
JournalAmerican Journal of Kidney Diseases
Volume48
Issue number3
DOIs
StatePublished - Sep 1 2006
Externally publishedYes

Fingerprint

Nodular Nonsuppurative Panniculitis
Panniculitis
Biopsy
Interstitial Nephritis
Podocytes
Lipoproteins
Macrophages
Kidney
Lipids
Skin

Keywords

  • collapsing glomerulopathy
  • panniculitis
  • proteinuria
  • Weber-Christian disease

ASJC Scopus subject areas

  • Nephrology

Cite this

A Case of Weber-Christian Disease With Collapsing Glomerulopathy. / Nahar, Nilay; Pardo, Victoriano; Sadhu, Sanghamitra; Young, Larry; Gonzalez, Nora; Jaimes, Edgar A.

In: American Journal of Kidney Diseases, Vol. 48, No. 3, 01.09.2006, p. 484-488.

Research output: Contribution to journalArticle

Nahar, Nilay ; Pardo, Victoriano ; Sadhu, Sanghamitra ; Young, Larry ; Gonzalez, Nora ; Jaimes, Edgar A. / A Case of Weber-Christian Disease With Collapsing Glomerulopathy. In: American Journal of Kidney Diseases. 2006 ; Vol. 48, No. 3. pp. 484-488.
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