A Cap for Every Occasion: Alternative eIF4F Complexes

J. J David Ho, Stephen Lee

Research output: Contribution to journal › Short survey

11 Citations (Scopus)

Abstract

The eukaryotic translation initiation factor 4F (eIF4F) has become essentially synonymous with 5′ cap-dependent mRNA translation. Recent studies demonstrate that cells assemble variants of eIF4F to produce adaptive, cap-dependent translatomes during physiological conditions that inhibit eIF4F. These findings challenge us to reassess classical perceptions of cellular translational pathways.

Original languageEnglish (US)
Pages (from-to)821-823
Number of pages3
JournalTrends in Biochemical Sciences
Volume41
Issue number10
DOIs
StatePublished - Oct 1 2016

Fingerprint

Eukaryotic Initiation Factor-4F
Eukaryotic Initiation Factors
Protein Biosynthesis
Messenger RNA

Keywords

  • eIF4E
  • eIF4E2
  • eIF4F
  • eIF4G3
  • hypoxia
  • translation

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology

Cite this

A Cap for Every Occasion : Alternative eIF4F Complexes. / Ho, J. J David; Lee, Stephen.

In: Trends in Biochemical Sciences, Vol. 41, No. 10, 01.10.2016, p. 821-823.

Research output: Contribution to journal › Short survey

Ho, JJD & Lee, S 2016, 'A Cap for Every Occasion: Alternative eIF4F Complexes', Trends in Biochemical Sciences, vol. 41, no. 10, pp. 821-823. https://doi.org/10.1016/j.tibs.2016.05.009
Ho JJD, Lee S. A Cap for Every Occasion: Alternative eIF4F Complexes. Trends in Biochemical Sciences. 2016 Oct 1;41(10):821-823. https://doi.org/10.1016/j.tibs.2016.05.009
Ho, J. J David ; Lee, Stephen. / A Cap for Every Occasion : Alternative eIF4F Complexes. In: Trends in Biochemical Sciences. 2016 ; Vol. 41, No. 10. pp. 821-823.
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