A blind controlled trial of adrenocorticotropin and cerebral gangliosides in nerve regeneration in the rat

Jacob P. Verghese, W. G. Bradley, Hiroshi Mitsumoto, David Chad

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Rapid axonal regeneration and successful reinnervation of muscle and sensory end organs are the requisites for effective recovery from nerve lesions. Axonal regeneration has been reportedly accelerated by cerebral gangliosides and ACTH. We measured the rate of regeneration of sensory axons in rats after sciatic nerve crush by using the pinch test. We found no difference between rats treated with ACTH or gangliosides and the control group.

Original languageEnglish (US)
Pages (from-to)455-458
Number of pages4
JournalExperimental neurology
Volume77
Issue number2
DOIs
StatePublished - Aug 1982
Externally publishedYes

ASJC Scopus subject areas

  • Neurology
  • Developmental Neuroscience

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