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2020

Surface chemistry and spectroscopic studies of the native phenylalanine dehydrogenase Langmuir monolayer at the air/aqueous NaCl interface

da Silva, R. L. C. G., Sharma, S. K., Paudyal, S., Mintz, K. J., Caseli, L. & Leblanc, R. M., Feb 15 2020, In : Journal of Colloid And Interface Science. 560, p. 458-466 9 p.

Research output: Contribution to journalArticle

Surface chemistry
Monolayers
Enzymes
Air
Conformations
2019
1 Citation (Scopus)

Carbon Dots: Diverse Preparation, Application, and Perspective in Surface Chemistry

Zhou, Y., Mintz, K. J., Sharma, S. K. & Leblanc, R. M., Jun 20 2019, In : Langmuir. 35, 28, p. 9115-9132 18 p.

Research output: Contribution to journalArticle

Surface chemistry
Carbon
chemistry
preparation
carbon
5 Citations (Scopus)

Carbon Nitride Dots: A Selective Bioimaging Nanomaterial

Liyanage, P. Y., Graham, R. M., Pandey, R. R., Chusuei, C. C., Mintz, K. J., Zhou, Y., Harper, J. K., Wu, W., Wikramanayake, A. H., Vanni, S. & Leblanc, R. M., Jan 16 2019, In : Bioconjugate Chemistry. 30, 1, p. 111-123 13 p.

Research output: Contribution to journalArticle

Quantum Dots
Carbon nitride
Nanostructures
Nanostructured materials
Semiconductor quantum dots
3 Citations (Scopus)

Close-Packed Langmuir Monolayers of Saccharide-Based Carbon Dots at the Air-Subphase Interface

Seven, E. S., Sharma, S. K., Meziane, DI., Zhou, Y., Mintz, K. J., Pandey, R. R., Chusuei, C. C. & Leblanc, R., Jan 1 2019, In : Langmuir.

Research output: Contribution to journalArticle

monomolecular films
carbohydrates
Monolayers
Carbon
carbon
Synucleins
helices
Conformations
Spectrum Analysis
incidence
2 Citations (Scopus)

Conjugation of carbon dots with β-galactosidase enzyme: Surface chemistry and use in biosensing

Sharma, S. K., Micic, M., Li, S., Hoar, B., Paudyal, S., Zahran, E. M. & Leblanc, R. M., Sep 9 2019, In : Molecules. 24, 18, 3275.

Research output: Contribution to journalArticle

Open Access
Galactosidases
Surface chemistry
conjugation
enzymes
Carbon
4 Citations (Scopus)

Insights into the photoluminescence properties of gel-like carbon quantum dots embedded in poly(methyl methacrylate) polymer

Rodrigues, J., Pereira, S. O., Soreto Teixeira, S., Zhou, Y., Peng, Z., Liyanage, P. Y., Leblanc, R., Barros-Timmons, A. M. M. V., Costa, L. C., Costa, F. M. & Monteiro, T., Mar 1 2019, In : Materials Today Communications. 18, p. 32-38 7 p.

Research output: Contribution to journalArticle

Polymethyl Methacrylate
Polymethyl methacrylates
Semiconductor quantum dots
Photoluminescence
Polymers
1 Citation (Scopus)

Interfacial Behavior of Fumonisin B1 Toxin and Its Degradation on the Membrane

Sharma, S. K., Poudel Sharma, S., Miller, D., Parel, J-M. A. & Leblanc, R., Feb 19 2019, In : Langmuir. 35, 7, p. 2814-2820 7 p.

Research output: Contribution to journalArticle

monomolecular films
Monolayers
degradation
membranes
Membranes
1 Citation (Scopus)

Nanoparticle-mediated approaches for Alzheimer's disease pathogenesis, diagnosis, and therapeutics

Hettiarachchi, S. D., Zhou, Y., Seven, E., Lakshmana, M. K., Kaushik, A. K., Chand, H. S. & Leblanc, R. M., Nov 28 2019, In : Journal of Controlled Release. 314, p. 125-140 16 p.

Research output: Contribution to journalReview article

Nanoparticles
Alzheimer Disease
Pharmaceutical Preparations
Biological Availability
Therapeutics
4 Citations (Scopus)

Nanoparticle-mediated targeted drug delivery for breast cancer treatment

Liyanage, P. Y., Hettiarachchi, S. D., Zhou, Y., Ouhtit, A., Seven, E. S., Oztan, C. Y., Celik, E. & Leblanc, R., Apr 1 2019, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1871, 2, p. 419-433 15 p.

Research output: Contribution to journalReview article

Nanoparticles
Breast Neoplasms
Drug Delivery Systems
Pharmaceutical Preparations
Neoplasms

Nontoxic amphiphilic carbon dots as promising drug nanocarriers across the blood-brain barrier and inhibitors of β-amyloid

Zhou, Y., Liyanage, P. Y., Devadoss, D., Rios Guevara, L. R., Cheng, L., Graham, R. M., Chand, H. S., Al-Youbi, A. O., Bashammakh, A. S., El-Shahawi, M. S. & Leblanc, R. M., Dec 14 2019, In : Nanoscale. 11, 46, p. 22387-22397 11 p.

Research output: Contribution to journalArticle

Drug delivery
Amyloid
Carbon
Neurology
Pathology
3 Citations (Scopus)

Novel Curcumin inspired bis-chalcone promotes endoplasmic reticulum stress and glioblastoma neurosphere cell death

Sansalone, L., Veliz, E. A., Myrthil, N. G., Stathias, V., Walters, W., Torrens, I. I., Schürer, S. C., Vanni, S., Leblanc, R. M. & Graham, R. M., Mar 1 2019, In : Cancers. 11, 3, 357.

Research output: Contribution to journalArticle

Open Access
Chalcone
Endoplasmic Reticulum Stress
Curcumin
Glioblastoma
Cell Death
32 Citations (Scopus)

Recent development of carbon quantum dots regarding their optical properties, photoluminescence mechanism, and core structure

Mintz, K. J., Zhou, Y. & Leblanc, R., Mar 21 2019, In : Nanoscale. 11, 11, p. 4634-4652 19 p.

Research output: Contribution to journalReview article

Semiconductor quantum dots
Photoluminescence
Carbon
Optical properties
Quantum yield

Rose Bengal Photodynamic Antimicrobial Therapy for Patients With Progressive Infectious Keratitis: A Pilot Clinical Study

Naranjo, A., Arboleda, A., Martinez, J. D., Durkee, H., Aguilar, M. C., Relhan, N., Nikpoor, N., Galor, A., Dubovy, S. R., Leblanc, R., Flynn, H. W., Miller, D., Parel, J. M. & Amescua, G., Dec 2019, In : American journal of ophthalmology. 208, p. 387-396 10 p.

Research output: Contribution to journalArticle

Rose Bengal
Keratitis
Photochemotherapy
Corneal Transplantation
Re-Epithelialization
15 Citations (Scopus)

Size-dependent photocatalytic activity of carbon dots with surface-state determined photoluminescence

Zhou, Y., Zahran, E., Quiroga, B. A., Perez, J., Mintz, K. J., Peng, Z., Liyanage, P. Y., Pandey, R. R., Chusuei, C. C. & Leblanc, R., Jul 5 2019, In : Applied Catalysis B: Environmental. 248, p. 157-166 10 p.

Research output: Contribution to journalArticle

Surface states
Photoluminescence
Carbon
carbon
Degradation
11 Citations (Scopus)

Triple conjugated carbon dots as a nano-drug delivery model for glioblastoma brain tumors

Hettiarachchi, S. D., Graham, R. M., Mintz, K. J., Zhou, Y., Vanni, S., Peng, Z. & Leblanc, R. M., Jan 1 2019, In : Nanoscale. 11, 13, p. 6192-6205 14 p.

Research output: Contribution to journalArticle

Drug delivery
Transferrin
Tumors
Brain
Carbon
7 Citations (Scopus)

Tryptophan carbon dots and their ability to cross the blood-brain barrier

Mintz, K. J., Mercado, G., Zhou, Y., Ji, Y., Hettiarachchi, S. D., Liyanage, P. Y., Pandey, R. R., Chusuei, C. C., Dallman, J. & Leblanc, R., Apr 1 2019, In : Colloids and Surfaces B: Biointerfaces. 176, p. 488-493 6 p.

Research output: Contribution to journalArticle

blood-brain barrier
Aptitude
tryptophan
Blood-Brain Barrier
Tryptophan
2018
34 Citations (Scopus)

Cancer targeting and drug delivery using carbon-based quantum dots and nanotubes

Pardo, J., Peng, Z. & Leblanc, R., Jan 1 2018, In : Molecules. 23, 2, 378.

Research output: Contribution to journalReview article

Nanotubes
Quantum Dots
Drug Delivery Systems
Drug delivery
Semiconductor quantum dots
5 Citations (Scopus)

Carbon dots and gold nanoparticles based immunoassay for detection of alpha-L-fucosidase

Mintz, K., Waidely, E., Zhou, Y., Peng, Z., Al-Youbi, A. O., Bashammakh, A. S., El-Shahawi, M. S. & Leblanc, R., Jan 1 2018, (Accepted/In press) In : Analytica Chimica Acta.

Research output: Contribution to journalArticle

alpha-L-Fucosidase
immunoassay
Immunoassay
Gold
Nanoparticles
93 Citations (Scopus)

Crossing the blood-brain barrier with nanoparticles

Zhou, Y., Peng, Z., Seven, E. S. & Leblanc, R., Jan 28 2018, In : Journal of Controlled Release. 270, p. 290-303 14 p.

Research output: Contribution to journalReview article

Blood-Brain Barrier
Nanoparticles
Pharmaceutical Preparations
Drug Delivery Systems
Enbucrilate
8 Citations (Scopus)

Embedding carbon dots in superabsorbent polymers for additive manufacturing

Zhou, Y., Mintz, K. J., Oztan, C. Y., Hettiarachchi, S. D., Peng, Z., Seven, E. S., Liyanage, P. Y., De La Torre, S., Celik, E. & Leblanc, R., Aug 17 2018, In : Polymers. 10, 8, 921.

Research output: Contribution to journalArticle

carbopol 940
3D printers
Polyacrylates
Polymers
Carbon

Enhancement of thermoelectric figure of merit of Bi 2 Te 3 using carbon dots

Celik, E., Oztan, C., Zhou, Y., Leblanc, R., Genc, O. & Ballikaya, S., Jan 1 2018, Energy. American Society of Mechanical Engineers (ASME), (ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE); vol. 6B-2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Carbon
Semiconductor quantum dots
Thermal gradients
Conversion efficiency
Thermal conductivity
4 Citations (Scopus)

Photoinduced Electron Transfer in Carbon Dots with Long-Wavelength Photoluminescence

Mintz, K. J., Guerrero, B. & Leblanc, R., Jan 1 2018, (Accepted/In press) In : Journal of Physical Chemistry C.

Research output: Contribution to journalArticle

Photoluminescence
electron transfer
Carbon
photoluminescence
Wavelength
17 Citations (Scopus)

Photoluminescent Carbon Dots: A Mixture of Heterogeneous Fractions

Zhou, Y., Liyanage, P. Y., Geleroff, D. L., Peng, Z., Mintz, K. J., Hettiarachchi, S. D., Pandey, R. R., Chusuei, C. C., Blackwelder, P. L. & Leblanc, R., Jan 1 2018, (Accepted/In press) In : ChemPhysChem.

Research output: Contribution to journalArticle

Carbon
Acetone
Gels
gels
carbon
2 Citations (Scopus)

Quantification of Nucleic Acid Concentration in the Nanoparticle or Polymer Conjugates Using Circular Dichroism Spectroscopy

Peng, Z., Li, J., Li, S., Pardo, J., Zhou, Y., Al-Youbi, A. O., Bashammakh, A. S., El-Shahawi, M. S. & Leblanc, R., Feb 6 2018, In : Analytical Chemistry. 90, 3, p. 2255-2262 8 p.

Research output: Contribution to journalArticle

Circular dichroism spectroscopy
Nucleic Acids
Polymers
Nanoparticles
Dichroism
8 Citations (Scopus)

Surface Chemistry and Spectroscopic Study of a Cholera Toxin B Langmuir Monolayer

Sharma, S. K., Seven, E. S., Micic, M., Li, S. & Leblanc, R., Feb 20 2018, In : Langmuir. 34, 7, p. 2557-2564 8 p.

Research output: Contribution to journalArticle

cholera
monomolecular films
Cholera Toxin
Surface chemistry
Monolayers
4 Citations (Scopus)

Ultrasensitive Plasmonic Biosensors for Real-Time Parallel Detection of Alpha-L-Fucosidase and Cardiac-Troponin-I in Whole Human Blood

Han, X., Shokri Kojori, H., Leblanc, R. & Kim, S. J., Jul 3 2018, In : Analytical Chemistry. 90, 13, p. 7795-7799 5 p.

Research output: Contribution to journalArticle

alpha-L-Fucosidase
Troponin I
Biosensors
Blood
Biomarkers
2017
4 Citations (Scopus)

Alpha- l -Fucosidase Immunoassay for Early Detection of Hepatocellular Carcinoma

Waidely, E., Al-Youbi, A. O., Bashammakh, A. S., El-Shahawi, M. S. & Leblanc, R., Sep 5 2017, In : Analytical Chemistry. 89, 17, p. 9459-9466 8 p.

Research output: Contribution to journalArticle

alpha-L-Fucosidase
Assays
Blood
Enzyme kinetics
Quartz
19 Citations (Scopus)

A resorcinarene for inhibition of Aβ fibrillation

Han, X., Park, J., Wu, W., Malagon, A., Wang, L., Vargas, E., Wikramanayake, A., Houk, K. N. & Leblanc, R., 2017, In : Chemical Science. 8, 3, p. 2003-2009 7 p.

Research output: Contribution to journalArticle

Poisons
Cytotoxicity
Computational methods
resorcinarene
Amyloid
17 Citations (Scopus)

Biocompatible and blood-brain barrier permeable carbon dots for inhibition of Aβ fibrillation and toxicity, and BACE1 activity

Han, X., Jing, Z., Wu, W., Zou, B., Peng, Z., Ren, P., Wikramanayake, A., Lu, Z. & Leblanc, R., Sep 21 2017, In : Nanoscale. 9, 35, p. 12862-12866 5 p.

Research output: Contribution to journalArticle

Toxicity
Carbon
Amyloid Precursor Protein Secretases
Computational methods
Amyloid
14 Citations (Scopus)

Biosensors based on β-galactosidase enzyme: Recent advances and perspectives

Sharma, S. K. & Leblanc, R., Oct 15 2017, In : Analytical Biochemistry. 535, p. 1-11 11 p.

Research output: Contribution to journalReview article

Galactosidases
Biosensing Techniques
Biosensors
Enzymes
Industry
36 Citations (Scopus)

Carbon dots: Promising biomaterials for bone-specific imaging and drug delivery

Peng, Z., Miyanji, E. H., Zhou, Y., Pardo, J., Hettiarachchi, S. D., Li, S., Blackwelder, P. L., Skromne, I. & Leblanc, R., Nov 28 2017, In : Nanoscale. 9, 44, p. 17533-17543 11 p.

Research output: Contribution to journalArticle

Biocompatible Materials
Drug delivery
Biomaterials
Bone
Carbon
97 Citations (Scopus)

Carbon dots: Biomacromolecule interaction, bioimaging and nanomedicine

Peng, Z., Han, X., Li, S., Al-Youbi, A. O., Bashammakh, A. S., El-Shahawi, M. S. & Leblanc, R., Jul 15 2017, In : Coordination Chemistry Reviews. 343, p. 256-277 22 p.

Research output: Contribution to journalReview article

Medical nanotechnology
Drug delivery
Carbon
carbon
delivery
6 Citations (Scopus)

Characterization of Surface-Active Biofilm Protein BslA in Self-Assembling Langmuir Monolayer at the Air-Water Interface

Liu, W., Li, S., Wang, Z., Yan, E. C. Y. & Leblanc, R., Aug 1 2017, In : Langmuir. 33, 30, p. 7548-7555 8 p.

Research output: Contribution to journalArticle

biofilms
monomolecular films
Biofilms
assembling
Monolayers
25 Citations (Scopus)

Gel-like Carbon Dots: Characterization and their Potential Applications

Zhou, Y., Desserre, A., Sharma, S. K., Li, S., Marksberry, M. H., Chusuei, C., Blackwelder, P. L. & Leblanc, R., 2017, (Accepted/In press) In : ChemPhysChem.

Research output: Contribution to journalArticle

Carbon
Gels
gels
carbon
Quantum yield
31 Citations (Scopus)

Polymers in carbon dots: A review

Zhou, Y., Sharma, S. K., Peng, Z. & Leblanc, R., 2017, In : Polymers. 9, 2, p. 67 1 p.

Research output: Contribution to journalReview article

Polymers
Carbon
Photoluminescence
Biocompatibility
Semiconductor quantum dots

Recent Progress Toward the Spectroscopic Analysis of Biomacromolecule-Nanoparticle Interactions

Peng, Z., Li, S., Han, X., Al-Youbi, A. O., Bashammakh, A. S., El-Shahawi, M. S. & Leblanc, R., Jun 22 2017, Bioinspired and Biomimetic Supramolecular Chemistry. Elsevier Inc., Vol. 4. p. 649-666 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Spectroscopic analysis
Nanoparticles
Bioactivity
Biocompatibility
Nanotechnology
2 Citations (Scopus)

Rheology of a carbon dot gel

Ji, Y., Zhou, Y., Waidely, E., Desserre, A., Marksberry, M. H., Chusuei, C. C., Dar, A. A., Chat, O. A., Li, S. & Leblanc, R., Nov 1 2017, In : Inorganica Chimica Acta. 468, p. 119-124 6 p.

Research output: Contribution to journalArticle

Rheology
rheology
Carbon
Gels
gels
4 Citations (Scopus)

The Investigation on Resorcinarenes towards either Inhibiting or Promoting Insulin Fibrillation

Han, X., Tian, C., Gandra, I., Eslava, V., Galindres, D., Vargas, E. & Leblanc, R., Jan 1 2017, (Accepted/In press) In : Chemistry - A European Journal.

Research output: Contribution to journalArticle

Insulin
Assays
Circular dichroism spectroscopy
Atomic force microscopy
Molecules
2016
18 Citations (Scopus)

A narrow amide I vibrational band observed by sum frequency generation spectroscopy reveals highly ordered structures of a biofilm protein at the air/water interface

Wang, Z., Morales-Acosta, M. D., Li, S., Liu, W., Kanai, T., Liu, Y., Chen, Y. N., Walker, F. J., Ahn, C. H., Leblanc, R. & Yan, E. C. Y., Feb 18 2016, In : Chemical Communications. 52, 14, p. 2956-2959 4 p.

Research output: Contribution to journalArticle

Surface measurement
Biofilms
Vibrational spectra
Pressure measurement
Amides
tryptophan
phosphorescence
Tryptophan
peptides
Fluorescence
26 Citations (Scopus)

Crossing the blood-brain-barrier with transferrin conjugated carbon dots: A zebrafish model study

Li, S., Peng, Z., Dallman, J., Baker, J., Othman, A. M., Blackwelder, P. L. & Leblanc, R., Sep 1 2016, In : Colloids and Surfaces B: Biointerfaces. 145, p. 251-256 6 p.

Research output: Contribution to journalArticle

blood-brain barrier
Zebrafish
Transferrin
Blood-Brain Barrier
central nervous system
25 Citations (Scopus)

Determination of the composition, encapsulation efficiency and loading capacity in protein drug delivery systems using circular dichroism spectroscopy

Peng, Z., Li, S., Han, X., Al-Youbi, A. O., Bashammakh, A. S., El-Shahawi, M. S. & Leblanc, R., Sep 21 2016, In : Analytica Chimica Acta. 937, p. 113-118 6 p.

Research output: Contribution to journalArticle

Circular dichroism spectroscopy
encapsulation
Drug Delivery Systems
Circular Dichroism
Encapsulation
1 Citation (Scopus)

Fluorescence and phosphorescence of tryptophan in peptides of different length and sequence

Radotić, K., Melø, T. B., Leblanc, R., Yousef, Y. A. & Naqvi, K. R., Apr 1 2016, In : Journal of Photochemistry and Photobiology B: Biology. 157, p. 120-128 9 p.

Research output: Contribution to journalArticle

tryptophan
phosphorescence
Tryptophan
peptides
Fluorescence
19 Citations (Scopus)

Interactions between carbon nanomaterials and biomolecules

Han, X., Li, S., Peng, Z., Al-Yuobi, A. O., Bashammakh, A. S. O., El-Shahawi, M. S. & Leblanc, R., Jan 6 2016, In : Journal of Oleo Science. 65, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

Biomolecules
Nanostructured materials
Carbon
Graphite
Graphene
15 Citations (Scopus)
Tannins
Drug delivery
Fluorouracil
Polymers
Fabrication
45 Citations (Scopus)

Recent Development of Cardiac Troponin i Detection

Han, X., Li, S., Peng, Z., Othman, A. M. & Leblanc, R., Feb 26 2016, In : ACS Sensors. 1, 2, p. 106-114 9 p.

Research output: Contribution to journalReview article

Troponin
Troponin I
biomarkers
Biomarkers
myocardial infarction
29 Citations (Scopus)

Serum protein biomarkers relevant to hepatocellular carcinoma and their detection

Waidely, E., Al-Yuobi, A. R. O., Bashammakh, A. S., El-Shahawi, M. S. & Leblanc, R., Jan 7 2016, In : Analyst. 141, 1, p. 36-44 9 p.

Research output: Contribution to journalArticle

Biomarkers
biomarker
Blood Proteins
serum
Hepatocellular Carcinoma
1 Citation (Scopus)

Study of the Alpha-l-Fucosidase Langmuir Monolayer at the Air-Water Interface

Waidely, E., Al-Youbi, A. O., Bashammakh, A. S., El-Shahawi, M. S. & Leblanc, R. M., Dec 22 2016, In : The journal of physical chemistry. B. 120, 50, p. 12843-12849 7 p.

Research output: Contribution to journalArticle

alpha-L-Fucosidase
monomolecular films
enzymes
Monolayers
Enzymes
18 Citations (Scopus)

Synthesis, characterization and in vivo drug delivery study of a biodegradable nano-structured molecularly imprinted polymer based on cross-linker of fructose

Asadi, E., Abdouss, M., Leblanc, R., Ezzati, N., Wilson, J. N. & Kordestani, D., Aug 5 2016, In : Polymer. 97, p. 226-237 12 p.

Research output: Contribution to journalArticle

Fructose
olanzapine
Drug delivery
Polymers
Brain