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2019

A prospective study of the immune reconstitution inflammatory syndrome (IRIS) in HIV-infected children from high prevalence countries

on behalf of the P1073 team, Jan 1 2019, In : PloS one. 14, 7, e0211155.

Research output: Contribution to journalArticle

Open Access
Immune Reconstitution Inflammatory Syndrome
Pediatrics
Biomarkers
prospective studies
Logistics
1 Citation (Scopus)
Methamphetamine
Cannabis
HIV Infections
Monocytes
HIV

Compromised steady-state germinal center activity with age in nonhuman primates

Shankwitz, K., Pallikkuth, S., Sirupangi, T., Kirk Kvistad, D., Russel, K. B., Pahwa, R., Gama, L., Koup, R. A., Pan, L., Villinger, F., Pahwa, S. & Petrovas, C., Jan 1 2019, (Accepted/In press) In : Aging Cell. e13087.

Research output: Contribution to journalArticle

Open Access
Germinal Center
Primates
B-Lymphocytes
Cell Aging
T-Lymphocytes

Current challenges and solutions in research and clinical care of older persons living with HIV: Findings presented at the 9th international workshop on HIV and aging

Sundermann, E. E., Erlandson, K. M., Pope, C. N., Rubtsova, A., Montoya, J., Moore, A. A., Marzolini, C., O'Brien, K. K., Pahwa, S., Payne, B. A. I., Rubin, L. H., Walmsley, S., Haughey, N. J., Montano, M., Karris, M. Y., Margolick, J. B. & Moore, D. J., Nov 1 2019, In : AIDS research and human retroviruses. 35, 11-12, p. 985-998 14 p.

Research output: Contribution to journalArticle

Open Access
HIV
Education
Research
Polypharmacy
Menopause
2 Citations (Scopus)

Dysfunctional peripheral T follicular helper cells dominate in people with impaired influenza vaccine responses: Results from the FLORAH study

Pallikkuth, S., De Armas, L. R., Rinaldi, S., George, V. K., Pan, L., Arheart, K. L., Pahwa, R. & Pahwa, S. G., May 1 2019, In : PLoS biology. 17, 5, e3000257.

Research output: Contribution to journalArticle

Open Access
Influenza Vaccines
Helper-Inducer T-Lymphocytes
Inducible T-Cell Co-Stimulator Protein
influenza
Vaccines

Harvard HIV and aging workshop: Perspectives and Priorities from Claude D. Pepper Centers and Centers for AIDS Research

Montano, M., Bhasin, S., D'Aquila, R. T., Erlandson, K. M., Evans, W. J., Funderburg, N. T., Justice, A., Ndhlovu, L. C., Ojikutu, B., Pahor, M., Pahwa, S., Ryan, A. S., Schrack, J., Schultz, M. B., Sebastiani, P., Sinclair, D. A., Tripp, J., Walker, B., Womack, J. A., Yung, R. & 1 others, Reeves, R. K., Nov 1 2019, In : AIDS research and human retroviruses. 35, 11-12, p. 999-1012 14 p.

Research output: Contribution to journalArticle

Open Access
Acquired Immunodeficiency Syndrome
HIV
Education
Research
HIV Infections

HIV and carotid atherosclerosis: a mediational model

Alcaide, M. L., Rodriguez, V. J., Abbamonte, J. M., Pallikuth, S., Langlie, J., Soni, M., Weiss, S. M., Hurwitz, B. E., Pahwa, S., Jones, D. L. & Kumar, M., Jan 1 2019, (Accepted/In press) In : AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV.

Research output: Contribution to journalArticle

Carotid Artery Diseases
Cocaine
HIV
path analysis
cause of death
1 Citation (Scopus)

HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells

Hyun, J., McMahon, R. S., Lang, A. L., Edwards, J. S., Badilla, A. D., Greene, M. E., Stone, G. W., Pallikkuth, S., Stevenson, M., Dykxhoorn, D. M., Kottilil, S., Pahwa, S. & Thomas, E., Jul 1 2019, In : PLoS pathogens. 15, 7, p. e1007883

Research output: Contribution to journalArticle

Open Access
Kupffer Cells
Myeloid Cells
Hepacivirus
HIV
Inflammation
2 Citations (Scopus)

Human Immunodeficiency Virus (HIV)-Antibody repertoire estimates reservoir size and time of antiretroviral therapy initiation in virally suppressed perinatally HIV-infected children

Rocca, S., Zangari, P., Cotugno, N., De Rossi, A., Ferns, B., Petricone, D., Rinaldi, S., Giaquinto, C., Bernardi, S., Rojo, P., Rossi, P., Pahwa, S., Nastouli, E. & Palma, P., Mar 20 2019, In : Journal of the Pediatric Infectious Diseases Society. 8, 5, p. 433-438 6 p.

Research output: Contribution to journalArticle

HIV
Antibodies
Western Blotting
Therapeutics
DNA

Implications of immune checkpoint expression during aging in HIV-infected people on antiretroviral therapy

De Armas, L. R., Pallikkuth, S., Rinaldi, S., Pahwa, R. & Pahwa, S., Nov 1 2019, In : AIDS research and human retroviruses. 35, 11-12, p. 1112-1122 11 p.

Research output: Contribution to journalArticle

HIV
T-Lymphocytes
Therapeutics
Antigens
Influenza Vaccines
1 Citation (Scopus)

Pretransplant Levels of C-Reactive Protein, Soluble TNF Receptor-1, and CD38+HLADR+ CD8 T Cells Predict Risk of Allograft Rejection in HIV+ Kidney Transplant Recipients

Camargo, J. F., Pallikkuth, S., Moroz, I., Natori, Y., Alcaide, M. L., Rodriguez, A., Guerra, G., Burke, G. W. & Pahwa, S., Dec 2019, In : Kidney International Reports. 4, 12, p. 1705-1716 12 p.

Research output: Contribution to journalArticle

Open Access
Tumor Necrosis Factor Receptors
C-Reactive Protein
Allografts
HIV
T-Lymphocytes
2 Citations (Scopus)

Single Cell Profiling Reveals PTEN Overexpression in Influenza-Specific B cells in Aging HIV-infected individuals on Anti-retroviral Therapy

de Armas, L. R., Pallikkuth, S., Pan, L., Rinaldi, S., Cotugno, N., Andrews, S., Pahwa, R., McDermott, A. B., Palma, P. & Pahwa, S. G., Dec 1 2019, In : Scientific reports. 9, 1, 2482.

Research output: Contribution to journalArticle

Open Access
Cell Aging
Human Influenza
B-Lymphocytes
HIV
1-Phosphatidylinositol 4-Kinase
2018
15 Citations (Scopus)

Altered immune cell follicular dynamics in HIV infection following influenza vaccination

Moysi, E., Pallikkuth, S., De Armas, L. R., Gonzalez, L. E., Ambrozak, D., George, V., Huddleston, D., Pahwa, R., Koup, R. A., Petrovas, C. & Pahwa, S. G., Jul 2 2018, In : Journal of Clinical Investigation. 128, 7, p. 3171-3185 15 p.

Research output: Contribution to journalArticle

Human Influenza
HIV Infections
Helper-Inducer T-Lymphocytes
Vaccination
HIV

Cardiac morbidity in HIV infection is associated with checkpoint inhibitor LAG-3 on CD4 T cells

Pallikkuth, S., Pahwa, R., Kausalya, B., Saravanan, S., Pan, L., Vignesh, R., Iqbal, S., Solomon, S. S., Murugavel, K. G., Poongulali, S., Kumarasamy, N. & Pahwa, S. G., Jan 1 2018, In : PLoS One. 13, 10, p. e0206256

Research output: Contribution to journalArticle

T-cells
HIV infections
cardiac output
HIV Infections
morbidity
4 Citations (Scopus)

Circulating inflammatory monocytes contribute to impaired influenza vaccine responses in HIV-infected participants

George, V. K., Pallikkuth, S., Pahwa, R., De Armas, L. R., Rinaldi, S., Pan, L. & Pahwa, S. G., Jun 19 2018, In : AIDS. 32, 10, p. 1219-1228 10 p.

Research output: Contribution to journalArticle

Influenza Vaccines
Monocytes
HIV
Human Influenza
CC Chemokines
4 Citations (Scopus)

Effect of antiretroviral therapy on allele-associated Lp(a) level in women with HIV in the Women's Interagency HIV Study

Enkhmaa, B., Anuurad, E., Zhang, W., Li, C. S., Kaplan, R., Lazar, J., Merenstein, D., Karim, R., Aouizerat, B., Cohen, M., Butler, K., Pahwa, S. G., Ofotokun, I., Adimora, A. A., Golub, E. & Berglund, L., Jan 1 2018, In : Journal of Lipid Research. 59, 10, p. 1967-1976 10 p.

Research output: Contribution to journalArticle

Lipoprotein(a)
Viruses
Alleles
HIV
Therapeutics
7 Citations (Scopus)

Impact of aging and HIV infection on serologic response to seasonal influenza vaccination

Pallikkuth, S., De Armas, L. R., Pahwa, R., Rinaldi, S., George, V. K., Sanchez, C. M., Pan, L., Dickinson, G., Rodriguez, A. E., Fischl, M. A., Alcaide, M. L. & Pahwa, S. G., Jun 1 2018, In : AIDS. 32, 9, p. 1085-1094 10 p.

Research output: Contribution to journalArticle

Human Influenza
HIV Infections
Vaccination
HIV
Influenza Vaccines

Microbial Translocation and Immune Activation in HIV-1 Infected Pregnant Women

Mitchell, C. D., Dominguez, S., Roach, M., George, V., Rinaldi, S., Fischl, M. A., Potter, J. E., Tyson, B. & Pahwa, S. G., Jan 1 2018, In : Current HIV Research. 16, 3, p. 208-215 8 p.

Research output: Contribution to journalArticle

HIV-1
Pregnant Women
HIV
Biomarkers
Pregnancy
2 Citations (Scopus)

Psychosocial Correlates of Monocyte Activation and HIV Persistence in Methamphetamine Users

Grosgebauer, K., Salinas, J., Sharkey, M. E., Roach, M., Pallikkuth, S., Dilworth, S. E., Pahwa, S. G., Sengul, T., Stevenson, M. & Carrico, A., Jan 1 2018, (Accepted/In press) In : Journal of NeuroImmune Pharmacology.

Research output: Contribution to journalArticle

Methamphetamine
Monocytes
HIV
Psychology
DNA
4 Citations (Scopus)

Recent stimulant use and leukocyte gene expression in methamphetamine users with treated HIV infection

Carrico, A., Flentje, A., Kober, K., Lee, S., Hunt, P., Riley, E. D., Shoptaw, S., Flowers, E., Dilworth, S. E., Pahwa, S. G. & Aouizerat, B. E., Jan 1 2018, (Accepted/In press) In : Brain, Behavior, and Immunity.

Research output: Contribution to journalArticle

Methamphetamine
HIV Infections
Leukocytes
HIV
Gene Expression
6 Citations (Scopus)

Substance-associated elevations in monocyte activation among methamphetamine users with treated HIV infection

Carrico, A., Cherenack, E. M., Roach, M. E., Riley, E. D., Oni, O., DIlworth, S. E., Shoptaw, S., Hunt, P., Roy, S., Pallikkuth, S. & Pahwa, S. G., Mar 27 2018, In : AIDS. 32, 6, p. 767-771 5 p.

Research output: Contribution to journalArticle

Methamphetamine
HIV Infections
Monocytes
HIV
CD4 Lymphocyte Count
2017
5 Citations (Scopus)

Associations of Plasma Cytokine and Microbial Translocation Biomarkers With Immune Reconstitution Inflammatory Syndrome

AIDS Clinical Trials Group A5202 Study Team, Nov 27 2017, In : The Journal of infectious diseases. 216, 9, p. 1159-1163 5 p.

Research output: Contribution to journalArticle

Immune Reconstitution Inflammatory Syndrome
Biomarkers
Cytokines
CD4 Lymphocyte Count
Inflammation
2 Citations (Scopus)

Concomitant nevirapine impacts pharmacokinetic exposure to the antimalarial artemether-lumefantrine in African children

IMPAACT P1079 protocol team, Oct 1 2017, In : PLoS One. 12, 10, e0186589.

Research output: Contribution to journalArticle

Nevirapine
antimalarials
Pharmacokinetics
Antimalarials
pharmacokinetics
9 Citations (Scopus)
Bacterial Vaginosis
Therapeutic Irrigation
Cross-Sectional Studies
HIV
Cytokines
6 Citations (Scopus)

Immune development in HIV-exposed uninfected children born to HIV-infected women

Miyamoto, M., Gouvêa, A. F. T. B., Ono, E., Succi, R. C. M., Pahwa, S. G. & de Moraes-Pinto, M. I., Feb 28 2017, In : Revista do Instituto de Medicina Tropical de Sao Paulo. 59, e30.

Research output: Contribution to journalArticle

HIV
Parturition
HLA-DR Antigens
Granulocyte-Macrophage Colony-Stimulating Factor
T-Cell Antigen Receptor
15 Citations (Scopus)

Induction of il21 in peripheral t follicular helper cells is an indicator of influenza vaccine response in a previously vaccinated HIV-infected pediatric cohort

De Armas, L. R., Cotugno, N., Pallikkuth, S., Pan, L., Rinaldi, S., Sanchez, M. C., Gonzalez, L., Cagigi, A., Rossi, P., Palma, P. & Pahwa, S. G., Mar 1 2017, In : Journal of Immunology. 198, 5, p. 1995-2005 11 p.

Research output: Contribution to journalArticle

Influenza Vaccines
Helper-Inducer T-Lymphocytes
HIV
Pediatrics
Human Influenza
4 Citations (Scopus)

Lipoprotein(a) and HIV: Allele-specific apolipoprotein(a) levels predict carotid intima-media thickness in hiv-infected young women in the women's interagency HIV study

Enkhmaa, B., Anuurad, E., Zhang, W., Li, C. S., Kaplan, R., Lazar, J., Merenstein, D., Karim, R., Aouizerat, B., Cohen, M., Butler, K., Pahwa, S. G., Ofotokun, I., Adimora, A. A., Golub, E. & Berglund, L., May 1 2017, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 37, 5, p. 997-1004 8 p.

Research output: Contribution to journalArticle

Apoprotein(a)
Carotid Intima-Media Thickness
Lipoprotein(a)
Alleles
HIV
11 Citations (Scopus)

Paradoxical aging in HIV: Immune senescence of B Cells is most prominent in young age

Rinaldi, S., Pallikkuth, S., George, V. K., de Armas, L. R., Pahwa, R., Sanchez, C. M., Pallin, M. F., Pan, L., Cotugno, N., Dickinson, G., Rodriguez, A. E., Fischl, M. A., Alcaide, M. L., Gonzalez, L., Palma, P. & Pahwa, S. G., 2017, In : Aging. 9, 4, p. 1307-1325 19 p.

Research output: Contribution to journalArticle

B-Lymphocytes
HIV
Human Influenza
Vaccination
Antibody-Producing Cells
7 Citations (Scopus)

Perturbation of B cell gene expression persists in HIV-infected children despite effective antiretroviral therapy and predicts H1N1 response

Cotugno, N., De Armas, L., Pallikkuth, S., Rinaldi, S., Issac, B., Cagigi, A., Rossi, P., Palma, P. & Pahwa, S. G., Sep 11 2017, In : Frontiers in Immunology. 8, SEP, 1083.

Research output: Contribution to journalArticle

B-Lymphocytes
Gene Expression
Vaccination
B-Lymphocyte Subsets
Therapeutics
13 Citations (Scopus)

T follicular helper cells and B cell dysfunction in aging and HIV-1 infection

Pallikkuth, S., de Armas, L., Rinaldi, S. & Pahwa, S. G., Oct 23 2017, In : Frontiers in Immunology. 8, OCT, 1380.

Research output: Contribution to journalShort survey

Helper-Inducer T-Lymphocytes
HIV Infections
HIV-1
B-Lymphocytes
HIV
2016
5 Citations (Scopus)

A survey of tuberculosis infection control practices at the NIH/NIAID/DAIDS-supported clinical trial sites in low and middle income countries

HIV Network Coordinating (HANC) TB Diagnostic Laboratory Working Division of AIDS, National Institute of Allergy and Infectious Diseases, Jun 10 2016, In : BMC Infectious Diseases. 16, 1, 269.

Research output: Contribution to journalArticle

National Institute of Allergy and Infectious Diseases (U.S.)
Infection Control
Tuberculosis
Clinical Trials
Surveys and Questionnaires
7 Citations (Scopus)

A therapeutic HIV-1 vaccine enhances anti-HIV-1 immune responses in patients under highly active antiretroviral therapy

Tung, F. Y., Tung, J. K., Pallikkuth, S., Pahwa, S. G. & Fischl, M. A., Apr 27 2016, In : Vaccine. 34, 19, p. 2225-2232 8 p.

Research output: Contribution to journalArticle

AIDS Vaccines
Highly Active Antiretroviral Therapy
Human immunodeficiency virus 1
HIV-1
immune response
61 Citations (Scopus)
Helper-Inducer T-Lymphocytes
T-lymphocytes
HIV
T-Lymphocytes
therapeutics