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2019
35 Citations (Scopus)

An anti-CD3 antibody, teplizumab, in relatives at risk for type 1 diabetes

Herold, K. C., Bundy, B. N., Alice Long, S., Bluestone, J. A., DiMeglio, L. A., Dufort, M. J., Gitelman, S. E., Gottlieb, P. A., Krischer, J. P., Linsley, P. S., Marks, J. B., Moore, W., Moran, A., Rodriguez, H., Russell, W. E., Schatz, D., Skyler, J. S., Tsalikian, E., Wherrett, D. K., Ziegler, A. G. & 1 others, Greenbaum, C. J., Aug 15 2019, In : New England Journal of Medicine. 381, 7, p. 603-613 11 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Anti-Idiotypic Antibodies
Placebos
teplizumab
HLA-DR3 Antigen

Associations of HbA1c with the timing of C-peptide responses during the oral glucose tolerance test at the diagnosis of type 1 diabetes

Type 1 Diabetes Trial Net and Diabetes Prevention Trial-Type-1 (DPT-1) Study Groups, Jun 1 2019, In : Pediatric Diabetes. 20, 4, p. 408-413 6 p.

Research output: Contribution to journalArticle

C-Peptide
Glucose Tolerance Test
Type 1 Diabetes Mellitus
Hemoglobins
Area Under Curve

Bringing closure: towards achieving a better understanding of Israel

Rosenstock, J., Zimmet, P., Skyler, J. S., Atkinson, M., Schatz, D., Buse, J. B., Kahn, S., Hirsch, I. B., Leroith, D. & Alberti, K. G., Aug 17 2019, In : The Lancet. 394, 10198, 1 p.

Research output: Contribution to journalLetter

Open Access
Israel
1 Citation (Scopus)

Exploring patient preferences for adjunct-to-insulin therapy in type 1 diabetes

Perkins, B. A., Rosenstock, J., Skyler, J. S., Laffel, L. M., Cherney, D. Z., Mathieu, C., Pang, C., Wood, R., Kinduryte, O., George, J. T., Marquard, J. & Soleymanlou, N., Sep 1 2019, In : Diabetes care. 42, 9, p. 1716-1723 8 p.

Research output: Contribution to journalArticle

Sodium-Glucose Transport Proteins
Patient Preference
Type 1 Diabetes Mellitus
Insulin
Therapeutics

Imagining a better future for all people with type 1 diabetes mellitus

Korsgren, O., Skyler, J. S., Skog, O., Sundberg, F., Forsander, G. & Ludvigsson, J., Jan 1 2019, (Accepted/In press) In : Nature Reviews Endocrinology.

Research output: Contribution to journalComment/debate

Type 1 Diabetes Mellitus
32 Citations (Scopus)

International consensus on risk management of diabetic ketoacidosis in patients with type 1 diabetes treated with sodium-glucose cotransporter (SGLT) inhibitors

Danne, T., Garg, S., Peters, A. L., Buse, J. B., Mathieu, C., Pettus, J. H., Alexander, C. M., Battelino, T., Ampudia-Blasco, F. J., Bode, B. W., Cariou, B., Close, K. L., Dandona, P., Dutta, S., Ferrannini, E., Fourlanos, S., Grunberger, G., Heller, S. R., Henry, R. R., Kurian, M. J. & 10 others, Kushner, J. A., Oron, T., Parkin, C. G., Pieber, T. R., Rodbard, H. W., Schatz, D., Skyler, J. S., Tamborlane, W. V., Yokote, K. & Phillip, M., Jan 1 2019, In : Diabetes care. 42, 6, p. 1147-1154 8 p.

Research output: Contribution to journalArticle

Open Access
Sodium-Glucose Transport Proteins
Diabetic Ketoacidosis
Risk Management
Type 1 Diabetes Mellitus
Glycosylated Hemoglobin A
4 Citations (Scopus)

Low-dose anti-thymocyte globulin preserves C-peptide, reduces HbA1c, and increases regulatory to conventional T-cell ratios in new-onset type 1 diabetes: Two-year clinical trial data

Type 1 Diabetes TrialNet ATG-GCSF Study Group, Jun 1 2019, In : Diabetes. 68, 6, p. 1267-1276 10 p.

Research output: Contribution to journalArticle

Open Access
Antilymphocyte Serum
C-Peptide
Type 1 Diabetes Mellitus
Clinical Trials
T-Lymphocytes
2018
6 Citations (Scopus)

Abnormal neutrophil signature in the blood and pancreas of presymptomatic and symptomatic type 1 diabetes

Vecchio, F., Lo Buono, N., Stabilini, A., Nigi, L., Dufort, M. J., Geyer, S., Rancoita, P. M., Cugnata, F., Mandelli, A., Valle, A., Leete, P., Mancarella, F., Linsley, P. S., Krogvold, L., Herold, K. C., Larsson, H. E., Richardson, S. J., Morgan, N. G., Dahl-Jørgensen, K., Sebastiani, G. & 82 others, Dotta, F., Bosi, E., Bianconi, E., Bonfanti, R., Bonura, C., De Pellegrin, M., Frontino, G., Grogan, P., Laurenzi, A., Meschi, F., Ragogna, F., Rigamonti, A., Greenbaum, C. J., Atkinson, M., Baidal, D., Becker, D., Bingley, P., Buckner, J., Clements, M., Colman, P., DiMeglio, L., Gitelman, S., Goland, R., Gottlieb, P., Knip, M., Krischer, J., Lernmark, A., Moore, W., Moran, A., Muir, A., Palmer, J., Peakman, M., Philipson, L., Raskin, P., Redondo, M., Rodriguez, H., Russell, W., Spain, L., Schatz, D. A., Sosenko, J., Wentworth, J., Wherrett, D., Wilson, D., Winter, W., Ziegler, A., Anderson, M., Antinozzi, P., Benoist, C., Blum, J., Bourcier, K., Chase, P., Clare-Salzler, M., Clynes, R., Eisenbarth, G., Fathman, C. G., Grave, G., Hering, B., Insel, R., Kaufman, F., Kay, T., Leschek, E., Mahon, J., Marks, J. B., Nanto-Salonen, K., Nepom, G., Orban, T., Parkman, R., Pescovitz, M., Peyman, J., Pugliese, A., Roep, B., Roncarolo, M., Savage, P., Simell, O., Sherwin, R., Siegelman, M., Skyler, J. S., Steck, A., Thomas, J., Trucco, M., Wagner, J. & Battaglia, M., Sep 20 2018, In : JCI Insight. 3, 18, e122146.

Research output: Contribution to journalArticle

Open Access
Type 1 Diabetes Mellitus
Pancreas
Neutrophils
RNA Sequence Analysis
Gene Expression Profiling
1 Citation (Scopus)

Brief commentary: Confusing treatment guidelines for patients with type 2 diabetes

Hirsch, I. B. & Skyler, J. S., Aug 21 2018, In : Annals of Internal Medicine. 169, 4, 1 p.

Research output: Contribution to journalComment/debate

Type 2 Diabetes Mellitus
Guidelines
Therapeutics
108 Citations (Scopus)

Cardiovascular outcomes trials in type 2 diabetes: Where Do We Go From Here? Ref lections From a Diabetes Care Editors' Expert Forum

Cefalu, W. T., Kaul, S., Gerstein, H. C., Holman, R. R., Zinman, B., Skyler, J. S., Green, J. B., Buse, J. B., Inzucchi, S. E., Leiter, L. A., Raz, I., Rosenstock, J. & Riddle, M. C., Jan 1 2018, In : Diabetes Care. 41, 1, p. 14-31 18 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Drug Approval
Drug Industry
United States Food and Drug Administration
Pharmaceutical Preparations
46 Citations (Scopus)

Empagliflozin as adjunctive to insulin therapyin type 1 diabetes: The EASE trials

Rosenstock, J., Marquard, J., Laffel, L. M., Neubacher, D., Kaspers, S., Cherney, D. Z., Zinman, B., Skyler, J. S., George, J., Soleymanlou, N. & Perkins, B. A., Dec 1 2018, In : Diabetes Care. 41, 12, p. 2560-2569 10 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Insulin
Placebos
Hypoglycemia
Ketosis
5 Citations (Scopus)

In Response to Carter and Heinemann: Insulin Concentration in Vials Randomly Purchased in Pharmacies in the United States: Considerable Loss in the Cold Supply Chain

Petersen, M. P., Hirsch, I. B., Skyler, J. S., Ostlund, R. E. & Cefalu, W. T., Mar 1 2018, (Accepted/In press) In : Journal of diabetes science and technology.

Research output: Contribution to journalArticle

Medical problems
Supply chains
Insulin
16 Citations (Scopus)

Low-Dose Anti-Thymocyte Globulin (ATG) Preserves β-Cell Function and Improves HbA1c in New-Onset Type 1 Diabetes

Type 1 Diabetes TrialNet ATG-GCSF Study Group, Sep 1 2018, In : Diabetes Care. 41, 9, p. 1917-1925 9 p.

Research output: Contribution to journalArticle

Antilymphocyte Serum
Type 1 Diabetes Mellitus
C-Peptide
Granulocyte Colony-Stimulating Factor
Placebos
1 Citation (Scopus)

Sleeping oxygen saturation, rapid eye movement sleep, and the adaptation of postprandial metabolic function in insulin sensitive and resistant individuals without diabetes

Garcia, K. A., Wohlgemuth, W. K., Ferrannini, E., Mari, A., Gonzalez, A., Mendez, A. J., Bizzotto, R., Skyler, J. S., Schneiderman, N. & Hurwitz, B., Jul 1 2018, In : Physiology and Behavior. 191, p. 123-130 8 p.

Research output: Contribution to journalArticle

REM Sleep
Meals
Sleep
Insulin
Oxygen
7 Citations (Scopus)

The influence of body mass index and age on C-peptide at the diagnosis of type 1 diabetes in children who participated in the diabetes prevention trial-type 1

Sosenko, J. M., Geyer, S., Skyler, J. S., Rafkin, L., Ismail, H. M., Libman, I. M., Liu, Y. F., DiMeglio, L. A., Evans-Molina, C. & Palmer, J. P., May 1 2018, In : Pediatric Diabetes. 19, 3, p. 403-409 7 p.

Research output: Contribution to journalArticle

C-Peptide
Type 1 Diabetes Mellitus
Body Mass Index
Fasting
Glucose Tolerance Test
2017
2 Citations (Scopus)

Diabetes research and care through the ages

Zinman, B., Skyler, J. S., Riddle, M. C. & Ferrannini, E., Oct 1 2017, In : Diabetes Care. 40, 10, p. 1302-1313 12 p.

Research output: Contribution to journalArticle

Cardiovascular Diseases
Research
Direction compound
94 Citations (Scopus)

Differentiation of diabetes by pathophysiology, natural history, and prognosis

Skyler, J. S., Bakris, G. L., Bonifacio, E., Darsow, T., Eckel, R. H., Groop, L., Groop, P. H., Handelsman, Y., Insel, R. A., Mathieu, C., McElvaine, A. T., Palmer, J. P., Pugliese, A., Schatz, D. A., Sosenko, J. M., Wilding, J. P. H. & Ratner, R. E., Feb 1 2017, In : Diabetes. 66, 2, p. 241-255 15 p.

Research output: Contribution to journalReview article

Natural History
Systems Biology
Endocrinology
Allergy and Immunology
Type 1 Diabetes Mellitus
6 Citations (Scopus)

Dysglycemia and Index60 as prediagnostic end points for type 1 diabetes prevention trials

Nathan, B. M., Boulware, D., Geyer, S., Atkinson, M. A., Colman, P., Goland, R., Russell, W., Wentworth, J. M., Wilson, D. M., Evans-Molina, C., Wherrett, D., Skyler, J. S., Moran, A. & Sosenko, J. M., Nov 1 2017, In : Diabetes Care. 40, 11, p. 1494-1499 6 p.

Research output: Contribution to journalArticle

Glucose Tolerance Test
Type 1 Diabetes Mellitus
C-Peptide
Incidence
Glucose
12 Citations (Scopus)

Hope vs hype: where are we in type 1 diabetes?

Skyler, J. S., Dec 23 2017, (Accepted/In press) In : Diabetologia. p. 1-8 8 p.

Research output: Contribution to journalArticle

Hope
Type 1 Diabetes Mellitus
Islets of Langerhans
Insulin Infusion Systems
Pancreas Transplantation
1 Citation (Scopus)

Neurovascular uncoupling after rapid glycemic control as a trigger of the diabetic-uremic striatopallidal syndrome

Lizarraga, K. J., Adams, D., Judith Post, M., Skyler, J. S. & Singer, C., 2017, (Accepted/In press) In : Parkinsonism and Related Disorders.

Research output: Contribution to journalArticle

7 Citations (Scopus)

The shape of the glucose concentration curve during an oral glucose tolerance test predicts risk for type 1 diabetes

Type 1 Diabetes TrialNet Study Group, Sep 27 2017, (Accepted/In press) In : Diabetologia. p. 1-9 9 p.

Research output: Contribution to journalArticle

Glucose Tolerance Test
Type 1 Diabetes Mellitus
Glucose
C-Peptide
Autoantibodies
8 Citations (Scopus)

The Use of Electrochemiluminescence Assays to Predict Autoantibody and Glycemic Progression Toward Type 1 Diabetes in Individuals with Single Autoantibodies

Sosenko, J. M., Yu, L., Skyler, J. S., Krischer, J. P., Gottlieb, P. A., Boulware, D., Miao, D., Palmer, J. P. & Steck, A. K., Mar 1 2017, In : Diabetes Technology and Therapeutics. 19, 3, p. 183-187 5 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Autoantibodies
Natural History
Confidence Intervals
2016
6 Citations (Scopus)

Discovery of Phosphorylated Peripherin as a Major Humoral Autoantigen in Type 1 Diabetes Mellitus

Doran, T. M., Morimoto, J., Simanski, S., Koesema, E. J., Clark, L. F., Pels, K., Stoops, S. L., Pugliese, A., Skyler, J. S. & Kodadek, T., May 19 2016, In : Cell Chemical Biology. 23, 5, p. 618-628 11 p.

Research output: Contribution to journalArticle

Peripherins
Autoantigens
Medical problems
Type 1 Diabetes Mellitus
Antigens
9 Citations (Scopus)

Effect of ranolazine on glycaemic control in patients with type 2 diabetes treated with either glimepiride or metformin

Pettus, J., Mcnabb, B., Eckel, R. H., Skyler, J. S., Dhalla, A., Guan, S., Jochelson, P., Belardinelli, L. & Henry, R. H., May 1 2016, In : Diabetes, Obesity and Metabolism. 18, 5, p. 463-474 12 p.

Research output: Contribution to journalArticle

glimepiride
Metformin
Type 2 Diabetes Mellitus
Placebos
Glycosylated Hemoglobin A