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  • Charles Nemeroff

Abnormalities in corticotropin-releasing factor (CRF) in neurodegenerative diseases

De Souza, E. B., Bissette, G., Whitehouse, P. J., Powers, R. E., Price, D. L., Vale, W. & Nemeroff, C. B., Jan 1 2018, Corticotropin-Releasing Factor: Basic and Clinical Studies of a Neuropeptide. CRC Press, p. 335-349 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

A consensus statement on the use of ketamine in the treatment of mood disorders

for the American Psychiatric Association (APA) Council of Research Task Force on Novel Biomarkers and Treatments, Apr 1 2017, In : JAMA Psychiatry. 74, 4, p. 399-405 7 p.

Research output: Contribution to journalReview article

165 Scopus citations

Adult glucocorticoid receptor mRNA expression volatility in response to an acute stressor and juvenile CSF corticotropin-releasing factor: A pilot neurodevelopmental study

Syed, S. A., Smith, E. L. P., Batuman, O., Rosenblum, L. A., Owens, M. J., Nemeroff, C. B. & Coplan, J. D., Apr 24 2017, In : Neuroscience Letters. 647, p. 20-25 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

A health care workers mental health crisis line in the age of COVID-19

Feinstein, R. E., Kotara, S., Jones, B., Shanor, D. & Nemeroff, C. B., Aug 1 2020, In : Depression and anxiety. 37, 8, p. 822-826 5 p.

Research output: Contribution to journalReview article

Open Access

Amygdala Reactivity and Anterior Cingulate Habituation Predict Posttraumatic Stress Disorder Symptom Maintenance After Acute Civilian Trauma

Stevens, J. S., Kim, Y. J., Galatzer-Levy, I. R., Reddy, R., Ely, T. D., Nemeroff, C. B., Hudak, L. A., Jovanovic, T., Rothbaum, B. O. & Ressler, K. J., Jun 15 2017, In : Biological Psychiatry. 81, 12, p. 1023-1029 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

Antidepressant outcomes predicted by Genetic variation in corticotropin-releasing hormone binding protein

O'Connell, C. P., Goldstein-Piekarski, A. N., Nemeroff, C. B., Schatzberg, A. F., Debattista, C., Carrillo-Roa, T., Binder, E. B., Dunlop, B. W., Craighead, W. E., Mayberg, H. S. & Williams, L. M., Mar 1 2018, In : American Journal of Psychiatry. 175, 3, p. 251-261 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

A randomized, placebo-controlled 12-month trial of divalproex and lithium in treatment of outpatients with bipolar I disorder

For the Divalproex Maintenance Study Group, Jan 1 2019, Bipolar Disorder: The Science of Mental Health. Taylor and Francis, p. 241-250 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Association of prospective risk for chronic PTSD symptoms with low TNFa and IFNG concentrations in the immediate aftermath of trauma exposure

Michopoulos, V., Beurel, E., Gould, F., Dhabhar, F. S., Schultebraucks, K., Galatzer-Levy, I., Rothbaum, B. O., Ressler, K. J. & Nemeroff, C. B., Jan 1 2020, In : American Journal of Psychiatry. 177, 1, p. 58-65 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

A validated predictive algorithm of post-traumatic stress course following emergency department admission after a traumatic stressor

Schultebraucks, K., Shalev, A. Y., Michopoulos, V., Grudzen, C. R., Shin, S. M., Stevens, J. S., Maples-Keller, J. L., Jovanovic, T., Bonanno, G. A., Rothbaum, B. O., Marmar, C. R., Nemeroff, C. B., Ressler, K. J. & Galatzer-Levy, I. R., Jul 1 2020, In : Nature medicine. 26, 7, p. 1084-1088 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Balancing the Promise and Risks of Ketamine Treatment for Mood Disorders

Sanacora, G., Heimer, H., Hartman, D., Mathew, S. J., Frye, M., Nemeroff, C. & Robinson Beale, R., May 1 2017, In : Neuropsychopharmacology. 42, 6, p. 1179-1181 3 p.

Research output: Contribution to journalComment/debate

17 Scopus citations

Benefits of sequentially adding cognitive-behavioral therapy or antidepressant medication for adults with nonremitting depression

Dunlop, B. W., LoParo, D., Kinkead, B., Mletzko-Crowe, T., Cole, S. P., Nemeroff, C. B., Mayberg, H. S. & Craighead, W. E., Apr 2019, In : American Journal of Psychiatry. 176, 4, p. 275-286 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Biomarker-Guided Tailored Therapy

Lydiard, J. & Nemeroff, C. B., Jan 1 2019, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 199-224 26 p. (Advances in Experimental Medicine and Biology; vol. 1192).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Brain structural and amyloid correlates of recovery from semantic interference in cognitively normal individuals with or without family history of late-onset alzheimer’s disease

Abulafia, C., Loewenstein, D., Curiel-Cid, R., Duarte-Abritta, B., Sánchez, S. M., Vigo, D. E., Castro, M. N., Drucaroff, L. J., Vázquez, S., Sevlever, G., Nemeroff, C. B., Guinjoan, S. M. & Villarreal, M. F., Jan 1 2019, In : Journal of Neuropsychiatry and Clinical Neurosciences. 31, 1, p. 25-36 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Candidate Biomarkers of Suicide Crisis Syndrome: What to Test Next? A Concept Paper

Calati, R., Nemeroff, C. B., Lopez-Castroman, J., Cohen, L. J. & Galynker, I., Apr 21 2020, In : The international journal of neuropsychopharmacology. 23, 3, p. 192-205 14 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Child abuse and neglect: Stress responsivity and resilience. stress responsivity and resilience.

Syed, S. A., Cranshaw, M. & Nemeroff, C. B., Nov 1 2019, Stress Resilience: Molecular and Behavioral Aspects. Elsevier, p. 181-196 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Childhood trauma and METH abuse among men who have sex with men: Implications for intervention

Lopez-Patton, M., Kumar, M., Jones, D., Fonseca, M., Kumar, A. M. & Nemeroff, C. B., Jan 1 2016, In : Journal of Psychiatric Research. 72, p. 1-5 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Childhood trauma predicts antidepressant response in adults with major depression: Data from the randomized international study to predict optimized treatment for depression

Williams, L. M., Debattista, C., Duchemin, A. M., Schatzberg, A. F. & Nemeroff, C. B., May 3 2016, In : Translational psychiatry. 6, e799.

Research output: Contribution to journalArticle

78 Scopus citations

Clinical implementation of pharmacogenetic decision support tools for antidepressant drug prescribing

Zeier, Z., Carpenter, L. L., Kalin, N. H., Rodriguez, C. I., McDonald, W. M., Widge, A. S. & Nemeroff, C. B., Sep 2018, In : American Journal of Psychiatry. 175, 9, p. 873-886 14 p.

Research output: Contribution to journalArticle

37 Scopus citations

Clinical outcome of maintenance electroconvulsive therapy in comorbid Posttraumatic Stress Disorder and major depressive disorder

Ahmadi, N., Moss, L., Hauser, P., Nemeroff, C. & Atre-Vaidya, N., Oct 2018, In : Journal of Psychiatric Research. 105, p. 132-136 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity

Carrillo-Roa, T., Labermaier, C., Weber, P., Herzog, D. P., Lareau, C., Santarelli, S., Wagner, K. V., Rex-Haffner, M., Harbich, D., Scharf, S. H., Nemeroff, C. B., Dunlop, B. W., Craighead, W. E., Mayberg, H. S., Schmidt, M. V., Uhr, M., Holsboer, F., Sillaber, I., Binder, E. B. & Müller, M. B., Dec 28 2017, In : PLoS biology. 15, 12, e2002690.

Research output: Contribution to journalArticle

7 Scopus citations

Convergent neurobiological predictors of mood and anxiety symptoms and treatment response

Jabbi, M. & Nemeroff, C. B., Jun 3 2019, In : Expert review of neurotherapeutics. 19, 6, p. 587-597 11 p.

Research output: Contribution to journalReview article

Correction: Lifetime stress accelerates epigenetic aging in an urban, African American cohort: Relevance of glucocorticoid signaling [Genome Biol., 16, 1, (2015) (266)] DOI: 10.1186/s13059-015-0828-5

Zannas, A. S., Arloth, J., Carrillo-Roa, T., Iurato, S., Röh, S., Ressler, K. J., Nemeroff, C. B., Smith, A. K., Bradley, B., Heim, C., Menke, A., Lange, J. F., Brückl, T., Ising, M., Wray, N. R., Erhardt, A., Binder, E. B. & Mehta, D., May 23 2018, In : Genome biology. 19, 1, 61.

Research output: Contribution to journalComment/debate

1 Scopus citations

Cortical thickness, brain metabolic activity, and in vivo amyloid deposition in asymptomatic, middle-aged offspring of patients with late-onset Alzheimer's disease

Duarte-Abritta, B., Villarreal, M. F., Abulafia, C., Loewenstein, D., Curiel Cid, R., Castro, M. N., Surace, E., Sánchez, S. M., Vigo, D. E., Vázquez, S., Nemeroff, C., Sevlever, G. & Guinjoan, S. M., Dec 1 2018, In : Journal of Psychiatric Research. 107, p. 11-18 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Corticotropin-releasing factor: Basic and clinical studies of a neuropeptide

De Souza, E. B. & Nemeroff, C. B., Jan 1 2018, CRC Press. 365 p.

Research output: Book/ReportBook

3 Scopus citations

Corticotropin-releasing factor: Cerebrospinal fluid studies

Bissett, G. & Nemeroff, C. B., Jan 1 2018, Corticotropin-Releasing Factor: Basic and Clinical Studies of a Neuropeptide. CRC Press, p. 327-333 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Corticotropin-Releasing Factor Receptor 1 Antagonism Is Ineffective for Women With Posttraumatic Stress Disorder

Dunlop, B. W., Binder, E. B., Iosifescu, D., Mathew, S. J., Neylan, T. C., Pape, J. C., Carrillo-Roa, T., Green, C., Kinkead, B., Grigoriadis, D., Rothbaum, B. O., Nemeroff, C. B. & Mayberg, H. S., Dec 15 2017, In : Biological Psychiatry. 82, 12, p. 866-874 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Defective Inflammatory Pathways in Never-Treated Depressed Patients Are Associated with Poor Treatment Response

Syed, S. A., Beurel, E., Loewenstein, D. A., Lowell, J. A., Craighead, W. E., Dunlop, B. W., Mayberg, H. S., Dhabhar, F., Dietrich, W. D., Keane, R. W., de Rivero Vaccari, J. P. & Nemeroff, C. B., Sep 5 2018, In : Neuron. 99, 5, p. 914-924.e3

Research output: Contribution to journalArticle

41 Scopus citations

Differences in adverse childhood experiences (ACEs) and quality of physical and mental health between transgender and cisgender sexual minorities

Schnarrs, P. W., Stone, A. L., Salcido, R., Baldwin, A. & Nemeroff, C. B., Dec 2019, In : Journal of Psychiatric Research. 119, p. 1-6 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Differential change on depressive symptom factors with antidepressant medication and cognitive behavior therapy for major depressive disorder

Dunlop, B. W., Cole, S. P., Nemeroff, C. B., Mayberg, H. S. & Craighead, W. E., Mar 15 2018, In : Journal of affective disorders. 229, p. 111-119 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Disrupted functional connectivity of the locus coeruleus in healthy adults with parental history of Alzheimer's disease

Del Cerro, I., Villarreal, M. F., Abulafia, C., Duarte-Abritta, B., Sánchez, S. M., Castro, M. N., Bocaccio, H., Ferrer, I., Menchón, J. M., Sevlever, G., Nemeroff, C. B., Soriano-Mas, C. & Guinjoan, S. M., Apr 2020, In : Journal of Psychiatric Research. 123, p. 81-88 8 p.

Research output: Contribution to journalArticle

DNA methylation levels are associated with CRF1 receptor antagonist treatment outcome in women with post-traumatic stress disorder

Pape, J. C., Carrillo-Roa, T., Rothbaum, B. O., Nemeroff, C. B., Czamara, D., Zannas, A. S., Iosifescu, D., Mathew, S. J., Neylan, T. C., Mayberg, H. S., Dunlop, B. W. & Binder, E. B., Nov 3 2018, In : Clinical Epigenetics. 10, 1, 136.

Research output: Contribution to journalArticle

5 Scopus citations

Double Trouble: Treatment Considerations for Patients with Comorbid PTSD and Depression

Rosen, V., Ortiz, N. F. & Nemeroff, C. B., Sep 1 2020, In : Current Treatment Options in Psychiatry. 7, 3, p. 258-274 17 p.

Research output: Contribution to journalReview article

Drug repositioning in glioblastoma: A pathway perspective

Tan, S. K., Jermakowicz, A., Mookhtiar, A. K., Nemeroff, C. B., Schürer, S. C. & Ayad, N. G., Mar 16 2018, In : Frontiers in Pharmacology. 9, MAR, 218.

Research output: Contribution to journalReview article

21 Scopus citations

EEG biomarkers for treatment response prediction in major depressive illness

Widge, A. S., Rodriguez, C. I., Carpenter, L. L., Kalin, N. H., McDonald, W. & Nemeroff, C. B., Jan 2019, In : American Journal of Psychiatry. 176, 1, p. 82 1 p.

Research output: Contribution to journalComment/debate

Effects of patient preferences on outcomes in the predictors of remission in depression to individual and combined treatments (PReDICT) Study

for the PReDICT Team, Jun 1 2017, In : American Journal of Psychiatry. 174, 6, p. 546-556 11 p.

Research output: Contribution to journalArticle

45 Scopus citations

EFFICACY AND LONG-TERM CLINICAL OUTCOME OF COMORBID POSTTRAUMATIC STRESS DISORDER AND MAJOR DEPRESSIVE DISORDER AFTER ELECTROCONVULSIVE THERAPY

Ahmadi, N., Moss, L., Simon, E., Nemeroff, C. & Atre-Vaidya, N., Jul 1 2016, In : Depression and Anxiety. 33, 7, p. 640-647 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Efficacy and safety of TS-121, a novel vasopressin V1B receptor antagonist, as adjunctive treatment for patients with major depressive disorder: A randomized, double-blind, placebo-controlled study

Kamiya, M., Sabia, H. D., Marella, J., Fava, M., Nemeroff, C. B., Umeuchi, H., Iijima, M., Chaki, S. & Nishino, I., Sep 2020, In : Journal of Psychiatric Research. 128, p. 43-51 9 p.

Research output: Contribution to journalArticle

Open Access

Electroencephalographic biomarkers for treatment response prediction in major depressive illness: A meta-analysis

Widge, A. S., Bilge, M. T., Montana, R., Chang, W., Rodriguez, C. I., Deckersbach, T., Carpenter, L. L., Kalin, N. H. & Nemeroff, C. B., Jan 2019, In : American Journal of Psychiatry. 176, 1, p. 44-56 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Erratum: More research needed on the association between genotype and antidepressant response: Response to Fabbri et al. (American Journal of Psychiatry (2018) DOI: 10.1176/appi.ajp.2018.18010070r)

O'Connell, C. P., Goldstein-Piekarski, A. N., Nemeroff, C. B., Schatzberg, A. F., Debattista, C., Carrillo-Roa, T., Binder, E. B., Dunlop, B. W., Craighead, W. E., Mayberg, H. S. & Williams, L. M., Jun 1 2018, In : American Journal of Psychiatry. 175, 7, 1 p.

Research output: Contribution to journalComment/debate

Executive functioning in cognitively normal middle-aged offspring of late-onset Alzheimer's disease patients

Abulafia, C., Fiorentini, L., Loewenstein, D. A., Curiel-Cid, R., Sevlever, G., Nemeroff, C. B., Villarreal, M. F., Vigo, D. E. & Guinjoan, S. M., May 2019, In : Journal of Psychiatric Research. 112, p. 23-29 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Failure to Recover from Proactive Semantic Interference and Abnormal Limbic Connectivity in Asymptomatic, Middle-Aged Offspring of Patients with Late-Onset Alzheimer's Disease

Śanchez, S. M., Abulafia, C., Duarte-Abritta, B., De Guevara, M. S. L., Castro, M. N., Drucaroff, L., Sevlever, G., Nemeroff, C. B., Vigo, D. E., Loewenstein, D. A., Villarreal, M. F. & Guinjoan, S. M., 2017, In : Journal of Alzheimer's Disease. 60, 3, p. 1183-1193 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Follow-up of monotherapy remitters in the PReDICT study: Maintenance treatment outcomes and clinical predictors of recurrence.

Kennedy, J. C., Dunlop, B. W., Craighead, L. W., Nemeroff, C. B., Mayberg, H. S. & Edward Craighead, W., Feb 1 2018, In : Journal of consulting and clinical psychology. 86, 2, p. 189-199 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Functional connectivity of the subcallosal cingulate cortex and differential outcomes to treatment with cognitive-behavioral therapy or antidepressant medication for major depressive disorder

Dunlop, B. W., Rajendra, J. K., Craighead, W. E., Kelley, M. E., McGrath, C. L., Choi, K. S., Kinkead, B., Nemeroff, C. B. & Mayberg, H. S., Jun 1 2017, In : American Journal of Psychiatry. 174, 6, p. 533-545 13 p.

Research output: Contribution to journalArticle

100 Scopus citations

Further study warranted to evaluate TNFa and IFNG as biomarkers for PTSD risk: Response to Na

Michopoulos, V., Ressler, K. J. & Nemeroff, C. B., Jan 1 2020, In : American Journal of Psychiatry. 177, 1, p. 93-94 2 p.

Research output: Contribution to journalLetter

Genome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans

Houtepen, L. C., Vinkers, C. H., Carrillo-Roa, T., Hiemstra, M., Van Lier, P. A., Meeus, W., Branje, S., Heim, C. M., Nemeroff, C. B., Mill, J., Schalkwyk, L. C., Creyghton, M. P., Kahn, R. S., Joëls, M., Binder, E. B. & Boks, M. P. M., Mar 21 2016, In : Nature communications. 7, 10967.

Research output: Contribution to journalArticle

86 Scopus citations

Hormonal treatments for major depressive disorder: State of the art

Dwyer, J. B., Aftab, A., Widge, A., Rodriguez, C. I., Carpenter, L. L., Nemeroff, C. B., McDonald, W. M. & Kalin, N. H., Aug 1 2020, In : American Journal of Psychiatry. 177, 8, p. 686-705 20 p.

Research output: Contribution to journalReview article

1 Scopus citations

Human amygdala engagement moderated by early life stress exposure is a biobehavioral target for predicting recovery on antidepressants

Goldstein-Piekarski, A. N., Korgaonkar, M. S., Green, E., Suppes, T., Schatzberg, A. F., Hastie, T., Nemeroff, C. B. & Williams, L. M., Oct 18 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 42, p. 11955-11960 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

Implementation of advanced methods for reproductive pharmacovigilance in autism: A meta-analysis of the effects of prenatal antidepressant exposure

Vega, M. L., Newport, G. C., Bozhdaraj, D., Saltz, S. B., Nemeroff, C. B. & Newport, D. J., Jun 2020, In : American Journal of Psychiatry. 177, 6, p. 506-517 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Insular functional alterations in emotional processing of schizophrenia patients revealed by Multivariate Pattern Analysis fMRI

Drucaroff, L. J., Fazzito, M. L., Castro, M. N., Nemeroff, C. B., Guinjoan, S. M. & Villarreal, M. F., Nov 2020, In : Journal of Psychiatric Research. 130, p. 128-136 9 p.

Research output: Contribution to journalArticle