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2019
115 Citations (Scopus)

Antithrombotic therapy after acute coronary syndrome or PCI in atrial fibrillation

Lopes, R. D., Heizer, G., Aronson, R., Vora, A. N., Massaro, T., Mehran, R., Goodman, S. G., Windecker, S., Darius, H., Li, J., Averkov, O., Bahit, M. C., Berwanger, O., Budaj, A., Hijazi, Z., Parkhomenko, A., Sinnaeve, P., Storey, R. F., Thiele, H., Vinereanu, D. & 486 others, Granger, C. B., Alexander, J. H., Hrabar, A. D., Caccavo, A., Licheri, A., Alvarisqueta, A. F., Abud, A. M., Estrada, C., Sueldo, C. P., Montenegro, E., Duronto, E. A., Blanco, F. L., Berra, F. C., Ferré Pácora, F. A., Lopez, G. M., Calvo, G., Azize, G. M., Luquez, H. A., Ramos, H., Colombo, H. R., Guetta, J. N., Resk, J. H., Medrano, J. C., Costabel, J. P., Carbajales, J., Schiavi, L. B., Saggia, L. I., Oliva, M. A., Casas, M., Snitman, M., Litvak Bruno, M. R., Cluigt, N., Vita, N. A., Guzman, P. N., Zangroniz, P. D., Villarreal, R. A., Bonato, R. R., Nani, S., Sassone, S. A., Macin, S. M., Arias, V. E., Alexopoulos, C., Brieger, D., Colquhoun, D., Heddle, W. F., Podczeck-Schweighofer, A., Ebner, C., Scherr, D., Lang, I. M., Huber, K., Guedes, A., Convens, C., Cools, F., Vercammen, J., Bartunek, J., Rossenbacker, T., Pereira, A. H., Kormann, A. M., Freitas, A. F., Fonseca, A. G. T., de Quadros, A., Janella, B. L., Kalil, C. A. A., Rodrigues, C. S., Precoma, D. B., Ramacciotti, E., Resende, E. S., Figueiredo, E. L., Manenti, E. R., Costa, F. A. D., Feitosa, G., Reis, H. J. L., Ribeiro, H. B., de Moraes, J. B. M. X., Dantas, J. M. M., Nicolau, J. C., Saraiva, J. F. K., Reolão, J., Piegas, L. S., Oliveira, L. F. A., Ritt, L. E. F., Braile, M. C. V. B., Dracoulakis, M. A., de Santos, M. O. N., Leães, P. E., Filho, P. P., Rech, R. L., Ueda, R., Silvestrini, T. L., Michalaros, Y. L., Manolova, A., Mihov, A. K., Yatseva, B., Velikov, C., Raev, D. H., Markov, D., Vassilev, D., Georgiev, E., Benov, H. O., Daskalov, I., Petrov, I. P., Milanova, M., Shehova-Yankova, N. S., Lazov, P. V., Beleva, S., Marchev, S. T., Gelev, V. L., Tyrrell, B., Wong, B., Dion, D., LaFlamme, D., Rupka, D. W., Shukla, D., Sabbah, E., Nadra, I. J., Bata, I., Cherry, J. M., Toleva, O., Dehghani, P., Vijayaraghavan, R., Welsh, R., Bagur, R., Labonte, R. E., Vizel, S., Fort, S., Huynh, T., Quan, V. H., Pesant, Y., Isaza, D., Accini Mendoza, J. L., Gomez, J. E., Jaramillo Gomez, N. I., Knezevic, A., Ruzic, A., Horvat, D., Milicic, D., Selthofer-Relatic, K., Pesek, K., Pravecek, M. K., Kovacic, M., Manola, S., Persic, V., Alan, D., Belohlavek, J., Larsen, C. T., Brønnum-Schou, J., Veien, K. T., Christensen, L. S., Maeng, M., Steffensen, R., Angoulvant, D., Beygui, F., Range, G., Cayla, G., Aupetit, J. F., Elbaz, M., Delarche, N., Meneveau, N., Ghanem, A., Hagendorff, A., Wilke, A., Hummel, A., Axthelm, C., Kadel, C., Langer, C., Stellbrink, C., Jacobshagen, C., Gross, C. M., Blessing, E. E. B., Minden, H. H., Bogossian, H., Wienbergen, H., Ebelt, H., Dreger, H., Ince, H., Akin, I., Eitel, I., Kreis, I., Appel, K. F., Maier, L., Bergmann, M., Moser, M., Toursarkissian, N., Menck, N., Ritter, O., Bernhardt, P., Nordbeck, P., Stöhring, R., Schwinger, R., Braun-Dullaeus, R. C., Maier, S. K. G., Schellong, S., Steiner, S., Rudolph, T., Dengler, T. J., Geisler, T., Rauch-Kröhnert, U., Jung, W., Jungmair, W., Komócsi, A., Papp, A., Vértes, A., Mohácsi, A., Herczeg, B., Merkely, B., Dézsi, C. A., Kis, E., Lakatos, F., Kerecsen, G., Piros, G. A., Takács, J., Tomcsányi, J., Keltai, K., Kovács, Z., Mathur, A., Baxi, H. A., Narendra, J., Gupta, J., Kumbla, M., Jamwal, N. K., Arora, P., Katz, A., Shotan, A., Schiff, E., Freedberg, N. A., Amir, O., Hussein, O., Kracoff, O. H., Alcalai, R., Adawi, S. Y., Viskin, S., Hayek, T., Hasin, Y., Rozenman, Y., Nam, C. W., Lee, C. W., Choi, D. J., Jeon, D. S., Park, H. W., Son, J. W., Jeong, J. O., Cha, K. S., Oh, S., Rha, S. W., Park, Y. H., On, Y. K., Bazzoni Ruiz, A. E., Valdespino, A. R., Castro Montes, B. E., Ramos Lopez, G. A., Llamas Esperón, G. A., Solache, G., Macías García, J. S., Leiva-Pons, J. L., De Los Rios Ibarra, M. O., Willems, F. F., Beyerbacht, H. P., van de Wal, R., Hysing, J., Lappegard, K. T., Vinge, L. E., Halvorsen, S., Pönitz, V., Chavez Ayala, C. A., Medina Palomino, F. A., Garcia Matheus, J. C., Włodarczak, A., Lubinski, A., Czarnecka, D., Wojciechowski, D., Skonieczny, G., Kasprzak, J. D., Wranicz, J. K., Szachniewicz, J., Kincel, K. K., Zmudka, K., Lesiak, M., Piekarski, M., Wujkowski, M., Lica-Gorzynska, M., Miekus, P., Feusette, P., Bartkowiak, R., Korzeniak, R., Sinkiewicz, W., Musial, W., Krolikowski, Z., Gaspar, A., Pinto, F., Almeida, F., Martinez, J., Brandão, L., Santos, L. M., Mateus, P., Monteiro, P., Pernencar, S., Mornoş, C., Olinic, D. M., Zdrenghea, D. T., Ortan, F. O., Cinteza, M., Popescu, M., Voicu, O., Todea, S. B. F., Babes, V., Vishnevskiy, A. Y., Kuimov, A. D., Duplyakov, D. V., Kosmacheva, E., Pokushalov, E., Gordeev, I. G., Zrazhevskiy, K. N., Sorokin, L. A., Ermoshkina, L. G., Zykov, M. V., Ruda, M. Y., Bulashova, O., Smolenskaya, O. G., Orlikova, O. V., Grishaev, S. L., Shalaev, S. V., Boldueva, S. A., Kuznetsov, V., Makukhin, V., Kostenko, V., Shvarts, Y., Kobalava, Z. D., Selakovic, A., Tosic, B. P., Sakac, D. B., Pavlovic, M., Dekleva, M., Tasic, N. M., Hinic, S., Jozic, T., Potpara, T., Dzupina, A., Pella, D., Majercak, I., Striezova, I., Fedacko, J., Gonsorcik, J., Fecik, J., Selecky, J., Antalik, L., Hranai, M., Gocar, M., Kokles, M., Oriesek, R., Regueiro, A., Ibánez, B., Djurovic, D. P., Gutierrez Ibañes, E., Ridocci-Soriano, F., Diaz Fernandez, J., Artaecheverria Zuazo, J. J., Escudier Villa, J. M., Nuñez Villota, J., Sanmartin Fernandez, M., Chinchurreta Capote, P. A., Muñoz Aguilera, R., Vera Ripoll, T., Mainar Tello, V., Björklund, F., Jensen, J., Andersson, J., Lauermann, J., Hamid, M., Angerås, O., Fischer, T. A., Yagensky, A. V., Goloborodko, B. I., Kyrychenko, I. I., Vakaliuk, I. P., Kovalskyy, I., Rishko, M. V., Sydor, N., Karpenko, O. I., Parkhomenko, O. M., Koval, O. A., Godlevska, O., Zhurba, S., Maslovskyi, V. Y., Netiazhenko, V. Z., Tashchuk, V. K., Shcherbak, V. P., Tseluyko, V. I., Cooke, A., Wrigley, B., Francis, C. M., Barr, C., Gorog, D. A., Lip, G. Y. H., Irving, J., Mills, J., Levy, T., Cheema, A. A., Salacata, A. S., Tenaglia, A. N., Meholick, A. W., Vedere, A. R., Patrello, A. J., Spaedy, A., Martin, A. C., Holland, B. H., Duffy, B. K., Schuler, B., Treasure, C. B., Paraboschi, C., Pickett, C. A., Rowan, C. J., Longnecker, C. R., Hess, C. N., Hinchman, D. A., Schneider, D. J., Murdock, D. K., Baldwin, D. E., Flores, E. A., Sirulnick, E. J., Ahmad, F., Aggarwala, G., Dhar, G., Kichura, G. M., Turitto, G., Sampognaro, G. C., Sharma, G. K., Chandna, H., Truong, H. T. D., Poock, J., Walia, J. S., Zelenka, J. T., Amin, J. K., Foucauld, J., Chambers, J., Abbott, J. D., Strobel, J. S., Dy, J. R., Nour, K. A., Sullenberger, L. E., Younis, L. T., Gonzales, L., Chane, M., Foster, M. T., King, M. Y., Grabarczyk, M. A., Izzo, M. R., Leesar, M. A., Bernabei, M. A., Cavender, M. D., Janik, M. J., Buchbinder, M., Arcarese, M., Yeh, M., Sheth, M. J., Sinno, M. C., Shoukfeh, M. F., Alhaddad, M., Ranadive, N. V., Jaffrani, N. A., Little, N. K., Shammas, N., Assi, N. A., Almousalli, O., Chan, P., Horwitz, P. A., Rozeman, P. A., Singh, P., Aggarwal, R., Gopinathannair, R., Manshadi, R., Korabathina, R., Gilmore, R. M., Feldman, R. B., Schnitzler, R. N., Harrison, R. W., Gandhi, S. N., Graham, S., Krueger, S. K., Jones, S. E., Rowe, S. K., Bazaz, S. B., Haddad, T. M., Povsic, T. J., Badami, U. A., Abernethy, W. B. & Mirza, Z. A., Apr 18 2019, In : New England Journal of Medicine. 380, 16, p. 1509-1524 16 p.

Research output: Contribution to journalArticle

Percutaneous Coronary Intervention
Acute Coronary Syndrome
Atrial Fibrillation
Vitamin K
Aspirin
6 Citations (Scopus)

CONTROL: A randomized phase 2 study of obeticholic acid and atorvastatin on lipoproteins in nonalcoholic steatohepatitis patients

Pockros, P. J., Fuchs, M., Freilich, B., Schiff, E. R., Kohli, A., Lawitz, E. J., Hellstern, P. A., Owens-Grillo, J., Van Biene, C., Shringarpure, R., MacConell, L., Shapiro, D. & Cohen, D. E., Jan 1 2019, (Accepted/In press) In : Liver International.

Research output: Contribution to journalArticle

Lipoproteins
Hydroxymethylglutaryl-CoA Reductase Inhibitors
LDL Cholesterol
Fibrosis
Placebos
555 Citations (Scopus)

Dapagliflozin and cardiovascular outcomes in type 2 diabetes

DECLARE–TIMI 58 Investigators, Jan 24 2019, In : New England Journal of Medicine. 380, 4, p. 347-357 11 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Confidence Intervals
Placebos
Hospitalization
Heart Failure
2018
12 Citations (Scopus)

Deferred treatment with sofosbuvir–velpatasvir–voxilaprevir for patients with chronic hepatitis C virus who were previously treated with an NS5A inhibitor: an open-label substudy of POLARIS-1

Bourlière, M., Gordon, S. C., Schiff, E. R., Tran, T. T., Ravendhran, N., Landis, C. S., Hyland, R. H., Stamm, L. M., Zhang, J., Dvory-Sobol, H., Subramanian, G. M., Brainard, D. M., McHutchison, J. G., Serfaty, L., Thompson, A. J., Sepe, T. E., Curry, M. P., Reddy, K. R. & Manns, M. P., Jan 1 2018, (Accepted/In press) In : The Lancet Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Hepacivirus
Virus Diseases
Therapeutics
Placebos
6 Citations (Scopus)

Differentiation of hepatocyte-like cells from human pluripotent stem cells using small molecules

Asumda, F. Z., Hatzistergos, K. E., Dykxhoorn, D. M., Jakubski, S., Edwards, J., Thomas, E. & Schiff, E. R., May 1 2018, In : Differentiation. 101, p. 16-24 9 p.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Hepatocytes
Endoderm
Periodic Acid
Regenerative Medicine
20 Citations (Scopus)

Hepatitis B Virus Serum DNA and RNA Levels in Nucleos(t)ide Analog-Treated or Untreated Patients During Chronic and Acute Infection

Butler, E. K., Gersch, J., McNamara, A., Luk, K. C., Holzmayer, V., de Medina, M., Schiff, E. R., Kuhns, M. & Cloherty, G. A., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Hepatitis B virus
RNA
DNA
Infection
Serum
3 Citations (Scopus)

Obstacles to successful treatment of hepatitis C in uninsured patients from a minority population

DeBose-Scarlett, A., Balise, R., Kwon, D., Vadaparampil, S., Chen, X., Schiff, E. R., Ayala, G. P. & Thomas, E., Jun 28 2018, In : Journal of Translational Medicine. 16, 1, 178.

Research output: Contribution to journalArticle

Hepatitis C
Viruses
Insurance
Population
Therapeutics
12 Citations (Scopus)

Randomised clinical trial: emricasan versus placebo significantly decreases ALT and caspase activation in subjects with non-alcoholic fatty liver disease

Shiffman, M., Freilich, B., Vuppalanchi, R., Watt, K., Chan, J. L., Spada, A., Hagerty, D. T. & Schiff, E. R., Jan 1 2018, (Accepted/In press) In : Alimentary Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Caspases
Randomized Controlled Trials
Placebos
Transaminases
Keratin-18
10 Citations (Scopus)

Viral eradication is required for sustained improvement of patient-reported outcomes in patients with hepatitis C

Younossi, Z. M., Stepanova, M., Reddy, R., Manns, M. P., Bourliere, M., Gordon, S. C., Schiff, E. R., Tran, T., Younossi, I. & Racila, A., Jan 1 2018, (Accepted/In press) In : Liver International.

Research output: Contribution to journalArticle

Hepatitis C
Placebos
Patient Reported Outcome Measures
Therapeutics
Antiviral Agents
2017
3 Citations (Scopus)
Hepatitis C
Sexually Transmitted Diseases
contagious disease
mortality
minority
1501 Citations (Scopus)

Evolocumab and clinical outcomes in patients with cardiovascular disease

FOURIER Steering Committee and Investigators, May 4 2017, In : New England Journal of Medicine. 376, 18, p. 1713-1722 10 p.

Research output: Contribution to journalArticle

LDL Cholesterol
Cardiovascular Diseases
Placebos
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Stroke
219 Citations (Scopus)

Sofosbuvir, velpatasvir, and voxilaprevir for previously treated HCV infection

POLARIS-4 Investigators, Jun 1 2017, In : New England Journal of Medicine. 376, 22, p. 2134-2146 13 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepacivirus
Genotype
Antiviral Agents
velpatasvir

Supplement-induced liver injury

Schiff, E. R. & Navarro, V. J., Apr 1 2017, In : Gastroenterology and Hepatology. 13, 4, p. 245-247 3 p.

Research output: Contribution to journalComment/debate

Liver
Wounds and Injuries
2016
271 Citations (Scopus)

Daclatasvir with sofosbuvir and ribavirin for hepatitis C virus infection with advanced cirrhosis or post-liver transplantation recurrence

Poordad, F., Schiff, E. R., Vierling, J. M., Landis, C., Fontana, R. J., Yang, R., Mcphee, F., Hughes, E. A., Noviello, S. & Swenson, E. S., 2016, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Ribavirin
Virus Diseases
Hepacivirus
Liver Transplantation
Fibrosis

Early Detection of Steatohepatitis: Less Teeth NASHing and More Research?

Thomas, E. & Schiff, E. R., Jul 1 2016, In : Digestive Diseases and Sciences. 61, 7, p. 1788-1789 2 p.

Research output: Contribution to journalEditorial

Fatty Liver
Liver Cirrhosis
Early Diagnosis
Tooth
Research
121 Citations (Scopus)

Effectiveness of Simeprevir Plus Sofosbuvir, with or Without Ribavirin, in Real-World Patients with HCV Genotype 1 Infection

HCV-TARGET Study Group, Feb 1 2016, In : Gastroenterology. 150, 2, p. 419-429 11 p.

Research output: Contribution to journalArticle

Ribavirin
Hepacivirus
Genotype
Infection
Therapeutics
37 Citations (Scopus)

Efficacy of Sofosbuvir, Velpatasvir, and GS-9857 in Patients With Genotype 1 Hepatitis C Virus Infection in an Open-Label, Phase 2 Trial

Lawitz, E., Reau, N., Hinestrosa, F., Rabinovitz, M., Schiff, E. R., Sheikh, A., Younes, Z., Herring, R., Reddy, K. R., Tran, T., Bennett, M., Nahass, R., Yang, J. C., Lu, S., Dvory-Sobol, H., Stamm, L. M., Brainard, D. M., McHutchison, J. G., Pearlman, B., Shiffman, M. & 3 others, Hawkins, T., Curry, M. & Jacobson, I., Nov 1 2016, In : Gastroenterology. 151, 5, p. 893-901.e1

Research output: Contribution to journalArticle

Virus Diseases
Hepacivirus
Fibrosis
Confidence Intervals
Antiviral Agents
965 Citations (Scopus)

Empagliflozin and progression of kidney disease in type 2 diabetes

EMPA-REG OUTCOME Investigators, Jul 28 2016, In : New England Journal of Medicine. 375, 4, p. 323-334 12 p.

Research output: Contribution to journalArticle

Kidney Diseases
Type 2 Diabetes Mellitus
Kidney
Placebos
Albuminuria
15 Citations (Scopus)

Hepatitis B virus and DNA stimulation trigger a rapid innate immune response through NF-kB

Yoneda, M., Hyun, J., Jakubski, S., Saito, S., Nakajima, A., Schiff, E. R. & Thomas, E., Jul 15 2016, In : Journal of Immunology. 197, 2, p. 630-643 14 p.

Research output: Contribution to journalArticle

NF-kappa B
Innate Immunity
Hepatitis B virus
DNA
Liver

Hepatotoxicity by herbs: a practical review of a neglected disease

Donet, J. A., Sornmayura, K., Gulau, M. & Schiff, E. R., Oct 1 2016, In : Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru. 36, 4, p. 350-353 4 p.

Research output: Contribution to journalReview article

Neglected Diseases
Liver
Acute Liver Failure
Wounds and Injuries
Gastroenterology

Reply

Yoneda, M., Thomas, E. & Schiff, E. R., Mar 1 2016, In : Clinical Gastroenterology and Hepatology. 14, 3, p. 484-485 2 p.

Research output: Contribution to journalArticle

Elasticity Imaging Techniques
Chronic Hepatitis
Liver Cirrhosis
Ultrasonography
Obesity
130 Citations (Scopus)

Simeprevir plus sofosbuvir (12 and 8 weeks) in hepatitis C virus genotype 1-infected patients without cirrhosis: OPTIMIST-1, a phase 3, randomized study

Kwo, P., Gitlin, N., Nahass, R., Bernstein, D., Etzkorn, K., Rojter, S., Schiff, E. R., Davis, M., Ruane, P., Younes, Z., Kalmeijer, R., Sinha, R., Peeters, M., Lenz, O., Fevery, B., De La Rosa, G., Scott, J. & Witek, J., Aug 1 2016, In : Hepatology. 64, 2, p. 370-380 11 p.

Research output: Contribution to journalArticle

Hepacivirus
Fibrosis
Genotype
Therapeutics
Sofosbuvir