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  • Eugene R Schiff
2019

Antithrombotic therapy after acute coronary syndrome or PCI in atrial fibrillation

Lopes, R. D., Heizer, G., Aronson, R., Vora, A. N., Massaro, T., Mehran, R., Goodman, S. G., Windecker, S., Darius, H., Li, J., Averkov, O., Bahit, M. C., Berwanger, O., Budaj, A., Hijazi, Z., Parkhomenko, A., Sinnaeve, P., Storey, R. F., Thiele, H., Vinereanu, D. & 486 others, Granger, C. B., Alexander, J. H., Hrabar, A. D., Caccavo, A., Licheri, A., Alvarisqueta, A. F., Abud, A. M., Estrada, C., Sueldo, C. P., Montenegro, E., Duronto, E. A., Blanco, F. L., Berra, F. C., Ferré Pácora, F. A., Lopez, G. M., Calvo, G., Azize, G. M., Luquez, H. A., Ramos, H., Colombo, H. R., Guetta, J. N., Resk, J. H., Medrano, J. C., Costabel, J. P., Carbajales, J., Schiavi, L. B., Saggia, L. I., Oliva, M. A., Casas, M., Snitman, M., Litvak Bruno, M. R., Cluigt, N., Vita, N. A., Guzman, P. N., Zangroniz, P. D., Villarreal, R. A., Bonato, R. R., Nani, S., Sassone, S. A., Macin, S. M., Arias, V. E., Alexopoulos, C., Brieger, D., Colquhoun, D., Heddle, W. F., Podczeck-Schweighofer, A., Ebner, C., Scherr, D., Lang, I. M., Huber, K., Guedes, A., Convens, C., Cools, F., Vercammen, J., Bartunek, J., Rossenbacker, T., Pereira, A. H., Kormann, A. M., Freitas, A. F., Fonseca, A. G. T., de Quadros, A., Janella, B. L., Kalil, C. A. A., Rodrigues, C. S., Precoma, D. B., Ramacciotti, E., Resende, E. S., Figueiredo, E. L., Manenti, E. R., Costa, F. A. D., Feitosa, G., Reis, H. J. L., Ribeiro, H. B., de Moraes, J. B. M. X., Dantas, J. M. M., Nicolau, J. C., Saraiva, J. F. K., Reolão, J., Piegas, L. S., Oliveira, L. F. A., Ritt, L. E. F., Braile, M. C. V. B., Dracoulakis, M. A., de Santos, M. O. N., Leães, P. E., Filho, P. P., Rech, R. L., Ueda, R., Silvestrini, T. L., Michalaros, Y. L., Manolova, A., Mihov, A. K., Yatseva, B., Velikov, C., Raev, D. H., Markov, D., Vassilev, D., Georgiev, E., Benov, H. O., Daskalov, I., Petrov, I. P., Milanova, M., Shehova-Yankova, N. S., Lazov, P. V., Beleva, S., Marchev, S. T., Gelev, V. L., Tyrrell, B., Wong, B., Dion, D., LaFlamme, D., Rupka, D. W., Shukla, D., Sabbah, E., Nadra, I. J., Bata, I., Cherry, J. M., Toleva, O., Dehghani, P., Vijayaraghavan, R., Welsh, R., Bagur, R., Labonte, R. E., Vizel, S., Fort, S., Huynh, T., Quan, V. H., Pesant, Y., Isaza, D., Accini Mendoza, J. L., Gomez, J. E., Jaramillo Gomez, N. I., Knezevic, A., Ruzic, A., Horvat, D., Milicic, D., Selthofer-Relatic, K., Pesek, K., Pravecek, M. K., Kovacic, M., Manola, S., Persic, V., Alan, D., Belohlavek, J., Larsen, C. T., Brønnum-Schou, J., Veien, K. T., Christensen, L. S., Maeng, M., Steffensen, R., Angoulvant, D., Beygui, F., Range, G., Cayla, G., Aupetit, J. F., Elbaz, M., Delarche, N., Meneveau, N., Ghanem, A., Hagendorff, A., Wilke, A., Hummel, A., Axthelm, C., Kadel, C., Langer, C., Stellbrink, C., Jacobshagen, C., Gross, C. M., Blessing, E. E. B., Minden, H. H., Bogossian, H., Wienbergen, H., Ebelt, H., Dreger, H., Ince, H., Akin, I., Eitel, I., Kreis, I., Appel, K. F., Maier, L., Bergmann, M., Moser, M., Toursarkissian, N., Menck, N., Ritter, O., Bernhardt, P., Nordbeck, P., Stöhring, R., Schwinger, R., Braun-Dullaeus, R. C., Maier, S. K. G., Schellong, S., Steiner, S., Rudolph, T., Dengler, T. J., Geisler, T., Rauch-Kröhnert, U., Jung, W., Jungmair, W., Komócsi, A., Papp, A., Vértes, A., Mohácsi, A., Herczeg, B., Merkely, B., Dézsi, C. A., Kis, E., Lakatos, F., Kerecsen, G., Piros, G. A., Takács, J., Tomcsányi, J., Keltai, K., Kovács, Z., Mathur, A., Baxi, H. A., Narendra, J., Gupta, J., Kumbla, M., Jamwal, N. K., Arora, P., Katz, A., Shotan, A., Schiff, E., Freedberg, N. A., Amir, O., Hussein, O., Kracoff, O. H., Alcalai, R., Adawi, S. Y., Viskin, S., Hayek, T., Hasin, Y., Rozenman, Y., Nam, C. W., Lee, C. W., Choi, D. J., Jeon, D. S., Park, H. W., Son, J. W., Jeong, J. O., Cha, K. S., Oh, S., Rha, S. W., Park, Y. H., On, Y. K., Bazzoni Ruiz, A. E., Valdespino, A. R., Castro Montes, B. E., Ramos Lopez, G. A., Llamas Esperón, G. A., Solache, G., Macías García, J. S., Leiva-Pons, J. L., De Los Rios Ibarra, M. O., Willems, F. F., Beyerbacht, H. P., van de Wal, R., Hysing, J., Lappegard, K. T., Vinge, L. E., Halvorsen, S., Pönitz, V., Chavez Ayala, C. A., Medina Palomino, F. A., Garcia Matheus, J. C., Włodarczak, A., Lubinski, A., Czarnecka, D., Wojciechowski, D., Skonieczny, G., Kasprzak, J. D., Wranicz, J. K., Szachniewicz, J., Kincel, K. K., Zmudka, K., Lesiak, M., Piekarski, M., Wujkowski, M., Lica-Gorzynska, M., Miekus, P., Feusette, P., Bartkowiak, R., Korzeniak, R., Sinkiewicz, W., Musial, W., Krolikowski, Z., Gaspar, A., Pinto, F., Almeida, F., Martinez, J., Brandão, L., Santos, L. M., Mateus, P., Monteiro, P., Pernencar, S., Mornoş, C., Olinic, D. M., Zdrenghea, D. T., Ortan, F. O., Cinteza, M., Popescu, M., Voicu, O., Todea, S. B. F., Babes, V., Vishnevskiy, A. Y., Kuimov, A. D., Duplyakov, D. V., Kosmacheva, E., Pokushalov, E., Gordeev, I. G., Zrazhevskiy, K. N., Sorokin, L. A., Ermoshkina, L. G., Zykov, M. V., Ruda, M. Y., Bulashova, O., Smolenskaya, O. G., Orlikova, O. V., Grishaev, S. L., Shalaev, S. V., Boldueva, S. A., Kuznetsov, V., Makukhin, V., Kostenko, V., Shvarts, Y., Kobalava, Z. D., Selakovic, A., Tosic, B. P., Sakac, D. B., Pavlovic, M., Dekleva, M., Tasic, N. M., Hinic, S., Jozic, T., Potpara, T., Dzupina, A., Pella, D., Majercak, I., Striezova, I., Fedacko, J., Gonsorcik, J., Fecik, J., Selecky, J., Antalik, L., Hranai, M., Gocar, M., Kokles, M., Oriesek, R., Regueiro, A., Ibánez, B., Djurovic, D. P., Gutierrez Ibañes, E., Ridocci-Soriano, F., Diaz Fernandez, J., Artaecheverria Zuazo, J. J., Escudier Villa, J. M., Nuñez Villota, J., Sanmartin Fernandez, M., Chinchurreta Capote, P. A., Muñoz Aguilera, R., Vera Ripoll, T., Mainar Tello, V., Björklund, F., Jensen, J., Andersson, J., Lauermann, J., Hamid, M., Angerås, O., Fischer, T. A., Yagensky, A. V., Goloborodko, B. I., Kyrychenko, I. I., Vakaliuk, I. P., Kovalskyy, I., Rishko, M. V., Sydor, N., Karpenko, O. I., Parkhomenko, O. M., Koval, O. A., Godlevska, O., Zhurba, S., Maslovskyi, V. Y., Netiazhenko, V. Z., Tashchuk, V. K., Shcherbak, V. P., Tseluyko, V. I., Cooke, A., Wrigley, B., Francis, C. M., Barr, C., Gorog, D. A., Lip, G. Y. H., Irving, J., Mills, J., Levy, T., Cheema, A. A., Salacata, A. S., Tenaglia, A. N., Meholick, A. W., Vedere, A. R., Patrello, A. J., Spaedy, A., Martin, A. C., Holland, B. H., Duffy, B. K., Schuler, B., Treasure, C. B., Paraboschi, C., Pickett, C. A., Rowan, C. J., Longnecker, C. R., Hess, C. N., Hinchman, D. A., Schneider, D. J., Murdock, D. K., Baldwin, D. E., Flores, E. A., Sirulnick, E. J., Ahmad, F., Aggarwala, G., Dhar, G., Kichura, G. M., Turitto, G., Sampognaro, G. C., Sharma, G. K., Chandna, H., Truong, H. T. D., Poock, J., Walia, J. S., Zelenka, J. T., Amin, J. K., Foucauld, J., Chambers, J., Abbott, J. D., Strobel, J. S., Dy, J. R., Nour, K. A., Sullenberger, L. E., Younis, L. T., Gonzales, L., Chane, M., Foster, M. T., King, M. Y., Grabarczyk, M. A., Izzo, M. R., Leesar, M. A., Bernabei, M. A., Cavender, M. D., Janik, M. J., Buchbinder, M., Arcarese, M., Yeh, M., Sheth, M. J., Sinno, M. C., Shoukfeh, M. F., Alhaddad, M., Ranadive, N. V., Jaffrani, N. A., Little, N. K., Shammas, N., Assi, N. A., Almousalli, O., Chan, P., Horwitz, P. A., Rozeman, P. A., Singh, P., Aggarwal, R., Gopinathannair, R., Manshadi, R., Korabathina, R., Gilmore, R. M., Feldman, R. B., Schnitzler, R. N., Harrison, R. W., Gandhi, S. N., Graham, S., Krueger, S. K., Jones, S. E., Rowe, S. K., Bazaz, S. B., Haddad, T. M., Povsic, T. J., Badami, U. A., Abernethy, W. B. & Mirza, Z. A., Apr 18 2019, In : New England Journal of Medicine. 380, 16, p. 1509-1524 16 p.

Research output: Contribution to journalArticle

183 Scopus citations

CONTROL: A randomized phase 2 study of obeticholic acid and atorvastatin on lipoproteins in nonalcoholic steatohepatitis patients

Pockros, P. J., Fuchs, M., Freilich, B., Schiff, E., Kohli, A., Lawitz, E. J., Hellstern, P. A., Owens-Grillo, J., Van Biene, C., Shringarpure, R., MacConell, L., Shapiro, D. & Cohen, D. E., Nov 1 2019, In : Liver International. 39, 11, p. 2082-2093 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Dapagliflozin and cardiovascular outcomes in type 2 diabetes

DECLARE–TIMI 58 Investigators, Jan 24 2019, In : New England Journal of Medicine. 380, 4, p. 347-357 11 p.

Research output: Contribution to journalArticle

801 Scopus citations

Viral eradication is required for sustained improvement of patient-reported outcomes in patients with hepatitis C

Younossi, Z. M., Stepanova, M., Reddy, R., Manns, M. P., Bourliere, M., Gordon, S. C., Schiff, E., Tran, T., Younossi, I. & Racila, A., Jan 2019, In : Liver International. 39, 1, p. 54-59 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
2018

Deferred treatment with sofosbuvir–velpatasvir–voxilaprevir for patients with chronic hepatitis C virus who were previously treated with an NS5A inhibitor: an open-label substudy of POLARIS-1

Bourlière, M., Gordon, S. C., Schiff, E. R., Tran, T. T., Ravendhran, N., Landis, C. S., Hyland, R. H., Stamm, L. M., Zhang, J., Dvory-Sobol, H., Subramanian, G. M., Brainard, D. M., McHutchison, J. G., Serfaty, L., Thompson, A. J., Sepe, T. E., Curry, M. P., Reddy, K. R. & Manns, M. P., Jan 1 2018, (Accepted/In press) In : The Lancet Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

13 Scopus citations

Differentiation of hepatocyte-like cells from human pluripotent stem cells using small molecules

Asumda, F. Z., Hatzistergos, K. E., Dykxhoorn, D. M., Jakubski, S., Edwards, J., Thomas, E. & Schiff, E. R., May 1 2018, In : Differentiation. 101, p. 16-24 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Hepatitis B Virus Serum DNA andRNA Levels in Nucleos(t)ide Analog-Treated or Untreated Patients During Chronic and Acute Infection

Butler, E. K., Gersch, J., McNamara, A., Luk, K. C., Holzmayer, V., de Medina, M., Schiff, E., Kuhns, M. & Cloherty, G. A., Dec 2018, In : Hepatology. 68, 6, p. 2106-2117 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

Obstacles to successful treatment of hepatitis C in uninsured patients from a minority population

DeBose-Scarlett, A., Balise, R., Kwon, D., Vadaparampil, S., Chen, X., Schiff, E. R., Ayala, G. P. & Thomas, E., Jun 28 2018, In : Journal of Translational Medicine. 16, 1, 178.

Research output: Contribution to journalArticle

4 Scopus citations

Randomised clinical trial: emricasan versus placebo significantly decreases ALT and caspase activation in subjects with non-alcoholic fatty liver disease

Shiffman, M., Freilich, B., Vuppalanchi, R., Watt, K., Chan, J. L., Spada, A., Hagerty, D. T. & Schiff, E. R., Jan 1 2018, (Accepted/In press) In : Alimentary Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

19 Scopus citations
2017
3 Scopus citations

Evolocumab and clinical outcomes in patients with cardiovascular disease

FOURIER Steering Committee and Investigators, May 4 2017, In : New England Journal of Medicine. 376, 18, p. 1713-1722 10 p.

Research output: Contribution to journalArticle

1701 Scopus citations

Sofosbuvir, velpatasvir, and voxilaprevir for previously treated HCV infection

POLARIS-4 Investigators, Jun 1 2017, In : New England Journal of Medicine. 376, 22, p. 2134-2146 13 p.

Research output: Contribution to journalArticle

246 Scopus citations

Supplement-induced liver injury

Schiff, E. R. & Navarro, V. J., Apr 1 2017, In : Gastroenterology and Hepatology. 13, 4, p. 245-247 3 p.

Research output: Contribution to journalComment/debate

2016

Daclatasvir with sofosbuvir and ribavirin for hepatitis C virus infection with advanced cirrhosis or post-liver transplantation recurrence

Poordad, F., Schiff, E. R., Vierling, J. M., Landis, C., Fontana, R. J., Yang, R., Mcphee, F., Hughes, E. A., Noviello, S. & Swenson, E. S., May 1 2016, In : Hepatology. 63, 5, p. 1493-1505 13 p.

Research output: Contribution to journalArticle

278 Scopus citations

Early Detection of Steatohepatitis: Less Teeth NASHing and More Research?

Thomas, E. & Schiff, E. R., Jul 1 2016, In : Digestive Diseases and Sciences. 61, 7, p. 1788-1789 2 p.

Research output: Contribution to journalEditorial

Effectiveness of Simeprevir Plus Sofosbuvir, with or Without Ribavirin, in Real-World Patients with HCV Genotype 1 Infection

HCV-TARGET Study Group, Feb 1 2016, In : Gastroenterology. 150, 2, p. 419-429 11 p.

Research output: Contribution to journalArticle

127 Scopus citations

Efficacy of Sofosbuvir, Velpatasvir, and GS-9857 in Patients With Genotype 1 Hepatitis C Virus Infection in an Open-Label, Phase 2 Trial

Lawitz, E., Reau, N., Hinestrosa, F., Rabinovitz, M., Schiff, E. R., Sheikh, A., Younes, Z., Herring, R., Reddy, K. R., Tran, T., Bennett, M., Nahass, R., Yang, J. C., Lu, S., Dvory-Sobol, H., Stamm, L. M., Brainard, D. M., McHutchison, J. G., Pearlman, B., Shiffman, M. & 3 others, Hawkins, T., Curry, M. & Jacobson, I., Nov 1 2016, In : Gastroenterology. 151, 5, p. 893-901.e1

Research output: Contribution to journalArticle

38 Scopus citations

Empagliflozin and progression of kidney disease in type 2 diabetes

EMPA-REG OUTCOME Investigators, Jul 28 2016, In : New England Journal of Medicine. 375, 4, p. 323-334 12 p.

Research output: Contribution to journalArticle

1100 Scopus citations

Hepatitis B virus and DNA stimulation trigger a rapid innate immune response through NF-kB

Yoneda, M., Hyun, J., Jakubski, S., Saito, S., Nakajima, A., Schiff, E. R. & Thomas, E., Jul 15 2016, In : Journal of Immunology. 197, 2, p. 630-643 14 p.

Research output: Contribution to journalArticle

18 Scopus citations

Hepatotoxicity by herbs: a practical review of a neglected disease

Donet, J. A., Sornmayura, K., Gulau, M. & Schiff, E. R., Oct 1 2016, In : Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru. 36, 4, p. 350-353 4 p.

Research output: Contribution to journalReview article

Liver Retransplantation in Patients with HIV-1 Infection: An International Multicenter Cohort Study

The FIPSE/NIH HIVTR/ NEAT023 Investigators, Feb 1 2016, In : American Journal of Transplantation. 16, 2, p. 679-687 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Reply

Yoneda, M., Thomas, E. & Schiff, E. R., Mar 1 2016, In : Clinical Gastroenterology and Hepatology. 14, 3, p. 484-485 2 p.

Research output: Contribution to journalArticle

Simeprevir plus sofosbuvir (12 and 8 weeks) in hepatitis C virus genotype 1-infected patients without cirrhosis: OPTIMIST-1, a phase 3, randomized study

Kwo, P., Gitlin, N., Nahass, R., Bernstein, D., Etzkorn, K., Rojter, S., Schiff, E., Davis, M., Ruane, P., Younes, Z., Kalmeijer, R., Sinha, R., Peeters, M., Lenz, O., Fevery, B., De La Rosa, G., Scott, J. & Witek, J., Aug 1 2016, In : Hepatology. 64, 2, p. 370-380 11 p.

Research output: Contribution to journalArticle

135 Scopus citations