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  • Camillo Ricordi
2019

A Double Fail-Safe Approach to Prevent Tumorigenesis and Select Pancreatic β Cells from Human Embryonic Stem Cells

Qadir, M. M. F., Álvarez-Cubela, S., Belle, K., Sapir, T., Messaggio, F., Johnson, K. B., Umland, O., Hardin, D., Klein, D., Pérez-Álvarez, I., Sadiq, F., Alcázar, O., Inverardi, L. A., Ricordi, C., Buchwald, P., Fraker, C. A., Pastori, R. L. & Domínguez-Bendala, J., Mar 5 2019, In : Stem Cell Reports. 12, 3, p. 611-623 13 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Correction to: In vivo imaging of type 1 diabetes immunopathology using eye-transplanted islets in NOD mice (Diabetologia, (2019), 62, 7, (1237-1250), 10.1007/s00125-019-4879-0)

Abdulreda, M. H., Molano, R. D., Faleo, G., Lopez-Cabezas, M., Shishido, A., Ulissi, U., Fotino, C., Hernandez, L. F., Tschiggfrie, A., Aldrich, V. R., Tamayo-Garcia, A., Bayer, A. S., Ricordi, C., Caicedo, A., Buchwald, P., Pileggi, A. & Berggren, P. O., Jan 1 2019, In : Diabetologia.

Research output: Contribution to journalComment/debate

Influence of Vitamin D on Islet Autoimmunity and Beta-Cell Function in Type 1 Diabetes

Infante, M., Ricordi, C., Sanchez, J., Clare-Salzler, M. J., Padilla, N., Fuenmayor, V., Chavez, C., Alvarez, A., Baidal, D., Alejandro, R., Caprio, M. & Fabbri, A., Sep 11 2019, In : Nutrients. 11, 9

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

In vivo imaging of type 1 diabetes immunopathology using eye-transplanted islets in NOD mice

Abdulreda, M. H., Molano, R. D., Faleo, G., Lopez-Cabezas, M., Shishido, A., Ulissi, U., Fotino, C., Hernandez, L. F., Tschiggfrie, A., Aldrich, V. R., Tamayo-Garcia, A., Bayer, A. L., Ricordi, C., Caicedo-Vierkant, D. A., Buchwald, P., Pileggi, A. & Berggren, P. O., Jan 1 2019, In : Diabetologia.

Research output: Contribution to journalArticle

1 Scopus citations

Operational immune tolerance towards transplanted allogeneic pancreatic islets in mice and a non-human primate

Abdulreda, M. H., Berman, D. M., Shishido, A., Martin, C., Hossameldin, M., Tschiggfrie, A., Hernandez, L. F., Hernandez, A., Ricordi, C., Parel, J. M., Jankowska-Gan, E., Burlingham, W. J., Arrieta-Quintero, E. A., Perez, V. L., Kenyon, N. S. & Berggren, P. O., May 1 2019, In : Diabetologia. 62, 5, p. 811-821 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Proposed tandem effect of physical activity and sirtuin 1 and 3 activation in regulating glucose homeostasis

Pacifici, F., Di Cola, D., Pastore, D., Abete, P., Guadagni, F., Donadel, G., Bellia, A., Esposito, E., Salimei, C., Salimei, P. S., Ricordi, C., Lauro, D. & Della-Morte, D., Oct 1 2019, In : International journal of molecular sciences. 20, 19, 4748.

Research output: Contribution to journalReview article

Open Access

Serum copper profile in patients with type 1 diabetes in comparison to other metals

Squitti, R., Negrouk, V., Perera, M., Llabre, M. M., Ricordi, C., Rongioletti, M. C. A. & Mendez, A. J., Dec 1 2019, In : Journal of Trace Elements in Medicine and Biology. 56, p. 156-161 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

The role of vitamin D and omega-3 PUFAs in islet transplantation

Infante, M., Ricordi, C., Padilla, N., Alvarez, A., Linetsky, E., Lanzoni, G., Mattina, A., Bertuzzi, F., Fabbri, A., Baidal, D. & Alejandro, R., Dec 2019, In : Nutrients. 11, 12, 2937.

Research output: Contribution to journalArticle

Open Access

VITAL study: An incomplete picture?

Infante, M., Ricordi, C., Baidal, D. A., Alejandro, R., Lanzoni, G., Sears, B., Caprio, M. & Fabbri, A., Jan 1 2019, In : European review for medical and pharmacological sciences. 23, 7, p. 3142-3147 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Vitamin D and ω-3 Supplementations in Mediterranean Diet During the 1st Year of Overt Type 1 Diabetes: A Cohort Study

Cadario, F., Pozzi, E., Rizzollo, S., Stracuzzi, M., Beux, S., Giorgis, A., Carrera, D., Fullin, F., Riso, S., Rizzo, A. M., Montorfano, G., Bagnati, M., Dianzani, U., Caimmi, P., Bona, G. & Ricordi, C., Sep 9 2019, In : Nutrients. 11, 9

Research output: Contribution to journalArticle

Open Access
2018

Administration of Vitamin D and high dose of omega 3 to sustain remission of type 1 diabetes

Cadario, F., Savastio, S., Ricotti, R., Rizzo, A. M., Carrera, D., Maiuri, L. & Ricordi, C., Jan 1 2018, In : European review for medical and pharmacological sciences. 22, 2, p. 512-515 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Carnosine protects pancreatic beta cells and islets against oxidative stress damage

Miceli, V., Pampalone, M., Frazziano, G., Grasso, G., Rizzarelli, E., Ricordi, C., Casu, A., Iannolo, G. & Conaldi, P. G., Jan 1 2018, (Accepted/In press) In : Molecular and Cellular Endocrinology.

Research output: Contribution to journalArticle

8 Scopus citations

Chronic Liraglutide Administration Fails to Suppress Postprandial Glucagon Levels in Type 1 Diabetic Islet Allograft Recipients with Graft Dysfunction

Vendrame, F., Padilla, N., Peixoto, E., Baidal, D., Lagari-Libhaber, V., Gil, A. A., Mantero, A., Messinger, S., Ricordi, C. & Alejandro, R., Jan 1 2018, In : Transplantation. 102, 1, p. e39-e40

Research output: Contribution to journalLetter

Copper in Glucose Intolerance, Cognitive Decline, and Alzheimer's Disease

Squitti, R., Mendez, A., Ricordi, C., Siotto, M. & Goldberg, R., Jan 1 2018, (Accepted/In press) In : Alzheimer Disease and Associated Disorders.

Research output: Contribution to journalArticle

Divergent antioxidant capacity of human islet cell subsets: A potential cause of beta-cell vulnerability in diabetes and islet transplantation

Miki, A., Ricordi, C., Sakuma, Y., Yamamoto, T., Misawa, R., Mita, A., Molano, R., Vaziri, N. D., Pileggi, A. & Ichii, H., May 1 2018, In : PLoS One. 13, 5, e0196570.

Research output: Contribution to journalArticle

8 Scopus citations

Inflammasome Proteins in Serum and Serum-Derived Extracellular Vesicles as Biomarkers of Stroke

Kerr, N., García-Contreras, M., Abbassi, S., Mejias, N. H., Desousa, B. R., Ricordi, C., Dietrich, W. D., Keane, R. W. & de Rivero Vaccari, J. P., Sep 4 2018, In : Frontiers in Molecular Neuroscience. 11, 309.

Research output: Contribution to journalArticle

10 Scopus citations

Insulin-mimetic effects of short-term rapamycin in type 1 diabetic patients prior to islet transplantation

Benedini, S., Ermetici, F., Briganti, S., Codella, R., Terruzzi, I., Maffi, P., Caldara, R., Secchi, A., Nano, R., Piemonti, L., Alejandro, R., Ricordi, C. & Luzi, L., Apr 13 2018, (Accepted/In press) In : Acta Diabetologica. p. 1-8 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Islet-derived EATP fuels autoreactive CD8 + T cells and facilitates the onset of type 1 diabetes

Tezza, S., Nasr, M. B., D'Addio, F., Vergani, A., Usuelli, V., Falzoni, S., Bassi, R., Dellepiane, S., Fotino, C., Rossi, C., Maestroni, A., Solini, A., Corradi, D., Giani, E., Mameli, C., Bertuzzi, F., Pezzolesi, M. G., Wasserfall, C. H., Atkinson, M. A., Füchtbauer, E. M. & 7 others, Ricordi, C., Folli, F., Virgilio, F. D., Pileggi, A., Dhe-Paganon, S., Zuccotti, G. V. & Fiorina, P., Oct 1 2018, In : Diabetes. 67, 10, p. 2038-2053 16 p.

Research output: Contribution to journalArticle

4 Scopus citations

Islet-Like Structures Generated In Vitro from Adult Human Liver Stem Cells Revert Hyperglycemia in Diabetic SCID Mice

Navarro-Tableros, V., Gai, C., Gomez, Y., Giunti, S., Pasquino, C., Deregibus, M. C., Tapparo, M., Pitino, A., Tetta, C., Brizzi, M. F., Ricordi, C. & Camussi, G., Jan 1 2018, (Accepted/In press) In : Stem Cell Reviews and Reports.

Research output: Contribution to journalArticle

4 Scopus citations

Metabolomic changes in human adipose tissue derived products following non-enzymatic microfacturing

Garcia-Contreras, M., Messaggio, F., Mendez, A. J. & Ricordi, C., Jan 1 2018, In : European Review for Medical and Pharmacological Sciences. 22, 10, p. 3249-3260 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Microencapsulated adult porcine islets transplanted intraperitoneally in streptozotocin-diabetic non-human primates

Safley, S. A., Kenyon, N. S., Berman-Weinberg, D., Barber, G. F., Willman, M., Duncanson, S., Iwakoshi, N., Holdcraft, R., Gazda, L., Thompson, P., Badell, I. R., Sambanis, A., Ricordi, C. & Weber, C. J., Jan 1 2018, (Accepted/In press) In : Xenotransplantation.

Research output: Contribution to journalArticle

13 Scopus citations

Omega-3 PUFAs and vitamin D co-supplementation as a safe-effective therapeutic approach for core symptoms of autism spectrum disorder: case report and literature review

Infante, M., Sears, B., Rizzo, A. M., Mariani Cerati, D., Caprio, M., Ricordi, C. & Fabbri, A., Jan 1 2018, (Accepted/In press) In : Nutritional Neuroscience.

Research output: Contribution to journalArticle

3 Scopus citations

P2RY1/ALK3-Expressing Cells within the Adult Human Exocrine Pancreas Are BMP-7 Expandable and Exhibit Progenitor-like Characteristics

Qadir, M. M. F., Álvarez-Cubela, S., Klein, D., Lanzoni, G., García-Santana, C., Montalvo, A., Pláceres-Uray, F., Mazza, E. M. C., Ricordi, C., Inverardi, L. A., Pastori, R. & Dominguez-Bendala, J., Feb 27 2018, In : Cell Reports. 22, 9, p. 2455-2468 14 p.

Research output: Contribution to journalArticle

6 Scopus citations

Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point

Rodriguez Diaz, R., Molano, R., Weitz, J. R., Abdulreda, M. H., Berman-Weinberg, D., Leibiger, B., Leibiger, I. B., Kenyon, N. S., Ricordi, C., Pileggi, A., Caicedo-Vierkant, D. A. & Berggren, P. O., Mar 6 2018, In : Cell Metabolism. 27, 3, p. 549-558.e4

Research output: Contribution to journalArticle

27 Scopus citations

Regenerative Medicine in the State of Florida: Letter Outlining the Florida Organization for Regenerative Medicine

Bruce, C. J., Bu, G., Centanni, J. M., Davis, M. D., Dobson, J., Hare, J., Fields, G. B., Jove, R., Kenyon, N. S., Khan, A., March, K., Matosevic, S., Mahmood, A., Pepine, C. J., Ricordi, C., Shapiro, S. A., Zylberberg, C. & Zylberberg, E., Jul 1 2018, In : Stem cells translational medicine. 7, 7, p. 511-512 2 p.

Research output: Contribution to journalLetter

Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells

Odorico, J., Markmann, J., Melton, D., Greenstein, J., Hwa, A., Nostro, C., Rezania, A., Oberholzer, J., Pipeleers, D., Yang, L., Cowan, C., Huangfu, D., Egli, D., Ben-David, U., Vallier, L., Grey, S. T., Tang, Q., Roep, B., Ricordi, C., Naji, A. & 16 others, Orlando, G., Anderson, D. G., Poznansky, M., Ludwig, B., Tomei, A., Greiner, D. L., Graham, M., Carpenter, M., Migliaccio, G., D'Amour, K., Hering, B., Piemonti, L., Berney, T., Rickels, M., Kay, T. & Adams, A., Aug 1 2018, In : Transplantation. 102, 8, p. 1223-1229 7 p.

Research output: Contribution to journalReview article

6 Scopus citations
2017

Active subjects with autoimmune type 1 diabetes have better metabolic profiles than sedentary controls

Adamo, M., Codella, R., Casiraghi, F., Ferrulli, A., Macrì, C., Bazzigaluppi, E., Terruzzi, I., Inverardi, L. A., Ricordi, C. & Luzi, L., 2017, In : Cell Transplantation. 26, 1, p. 23-32 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Bioengineering of an intraabdominal endocrine pancreas

Baidal, D., Ricordi, C., Berman-Weinberg, D., Alvarez, A., Padilla, N., Ciancio, G., Linetsky, E., Pileggi, A. & Alejandro, R., May 11 2017, In : New England Journal of Medicine. 376, 19, 19.

Research output: Contribution to journalLetter

41 Scopus citations

Can Type 1 diabetes progression be halted? Possible role of high dose vitamin D and omega 3 fatty acids

Cadario, F., Savastio, S., Rizzo, A. M., Carrera, D., Bona, G. & Ricordi, C., Apr 1 2017, In : European Review for Medical and Pharmacological Sciences. 21, 7, p. 1604-1609 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Comprehensive metabolomics study to assess longitudinal biochemical changes and potential early biomarkers in nonobese diabetic mice that progress to diabetes

Buchwald, P., Tamayo-Garcia, A., Ramamoorthy, S., Garcia-Contreras, M., Mendez, A. J. & Ricordi, C., Oct 6 2017, In : Journal of Proteome Research. 16, 10, p. 3873-3890 18 p.

Research output: Contribution to journalArticle

4 Scopus citations

Diabetes and Alzheimer's Disease: Can Elevated Free Copper Predict the Risk of the Disease?

Squitti, R., Mendez, A. J., Simonelli, I. & Ricordi, C., 2017, In : Journal of Alzheimer's Disease. 56, 3, p. 1055-1064 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Does the Mesenchymal Stem Cell Source Influence Smooth Muscle Regeneration in Tissue-Engineered Urinary Bladders?

Pokrywczynska, M., Jundzill, A., Warda, K., Buchholz, L., Rasmus, M., Adamowicz, J., Bodnar, M., Marszalek, A., Helmin-Basa, A., Michalkiewicz, J., Gagat, M., Grzanka, A., Frontczak-Baniewicz, M., Gastecka, A. M., Kloskowski, T., Nowacki, M., Ricordi, C. & Drewa, T., Nov 1 2017, In : Cell Transplantation. 26, 11, p. 1780-1791 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Exosomes as biomarkers and therapeutic tools for type 1 diabetes mellitus

Garcia-Contreras, M., Brooks, R. W., Boccuzzi, L., Robbins, P. D. & Ricordi, C., Jun 1 2017, In : European Review for Medical and Pharmacological Sciences. 21, 12, p. 2940-2956 17 p.

Research output: Contribution to journalReview article

22 Scopus citations

Immunoisolation of murine islet allografts in vascularized sites through conformal coating with polyethylene glycol

Manzoli, V., Villa, C., Bayer, A. L., Morales, L. C., Molano, R., Torrente, Y., Ricordi, C., Hubbell, J. A. & Tomei, A., Jan 1 2017, (Accepted/In press) In : American Journal of Transplantation.

Research output: Contribution to journalArticle

18 Scopus citations

Islet transplantation for hypoglycemia unawareness/severe hypoglycemia: Caveat emptor

Hering, B. J., Bridges, N. D., Eggerman, T. L. & Ricordi, C., Aug 1 2017, In : Diabetes Care. 40, 8, p. e111-e112

Research output: Contribution to journalLetter

Metabolomics Study of the Effects of Inflammation, Hypoxia, and High Glucose on Isolated Human Pancreatic Islets

Garcia-Contreras, M., Tamayo-Garcia, A., Pappan, K. L., Michelotti, G. A., Stabler, C. L., Ricordi, C. & Buchwald, P., Jun 2 2017, In : Journal of Proteome Research. 16, 6, p. 2294-2306 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Plasma-derived exosome characterization reveals a distinct microRNA signature in long duration Type 1 diabetes

Garcia-Contreras, M., Shah, S. H., Tamayo, A., Robbins, P. D., Golberg, R. B., Mendez, A. J. & Ricordi, C., Dec 1 2017, In : Scientific Reports. 7, 1, 5998.

Research output: Contribution to journalArticle

30 Scopus citations
2016

A multicenter study: North american islet donor score in donor pancreas selection for human islet isolation for transplantation

Wang, L. J., Kin, T., O’Gorman, D., Shapiro, A. M. J., Naziruddin, B., Takita, M., Levy, M. F., Posselt, A. M., Szot, G. L., Savari, O., Barbaro, B., McGarrigle, J., Yeh, C., Oberholzer, J., Lei, J., Chen, T., Lian, M., Markmann, J. F., Alvarez, A., Linetsky, E. & 16 others, Ricordi, C., Balamurugan, A. N., Loganathan, G., Wilhelm, J. J., Hering, B. J., Bottino, R., Trucco, M., Liu, C., Min, Z., Li, Y., Naji, A., Fernandez, L. A., Ziemelis, M., Danobeitia, J. S., Millis, J. M. & Witkowski, P., 2016, In : Cell Transplantation. 25, 8, p. 1515-1523 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Bioengineering the endocrine pancreas: Intraomental islet transplantation within a biologic resorbable scaffold

Berman-Weinberg, D., Molano, R., Fotino, C., Ulissi, U., Gimeno, J., Mendez, A. J., Kenyon, N. M., Kenyon, N. S., Andrews, D., Ricordi, C. & Pileggi, A., May 1 2016, In : Diabetes. 65, 5, p. 1350-1361 12 p.

Research output: Contribution to journalArticle

46 Scopus citations

CD52-negative NK cells are abundant in the liver and less susceptible to alemtuzumab treatment

Hotta, R., Ohira, M., Matsuura, T., Muraoka, I., Tryphonopoulos, P., Fan, J., Tekin, A., Selvaggi, G., Levi, D., Ruiz, P., Ricordi, C., Vianna, R., Ohdan, H., Waldmann, H., Tzakis, A. G. & Nishida, S., Aug 1 2016, In : PLoS One. 11, 8, e0161618.

Research output: Contribution to journalArticle

3 Scopus citations

Clinical pancreatic islet transplantation

Shapiro, A. M. J., Pokrywczynska, M. & Ricordi, C., Nov 11 2016, (Accepted/In press) In : Nature Reviews Endocrinology.

Research output: Contribution to journalArticle

154 Scopus citations
17 Scopus citations

Effects of Composition of Alginate-Polyethylene Glycol Microcapsules and Transplant Site on Encapsulated Islet Graft Outcomes in Mice

Villa, C., Manzoli, V., Abreu, M. M., Verheyen, C. A., Seskin, M., Najjar, M., Molano, R., Torrente, Y., Ricordi, C. & Tomei, A., Aug 12 2016, (Accepted/In press) In : Transplantation.

Research output: Contribution to journalArticle

18 Scopus citations

Engineering human renal epithelial cells for transplantation in regenerative medicine

Manzoli, V., Colter, D. C., Dhanaraj, S., Fornoni, A., Ricordi, C., Pileggi, A. & Tomei, A., Dec 15 2016, (Accepted/In press) In : Medical Engineering and Physics.

Research output: Contribution to journalArticle

3 Scopus citations

Executive summary of IPITA-TTS opinion leaders report on the future of b-cell replacement

Markmann, J. F., Bartlett, S. T., Johnson, P., Korsgren, O., Hering, B. J., Scharp, D., Kay, T. W. H., Bromberg, J., Odorico, J. S., Weir, G. C., Bridges, N., Kandaswamy, R., Stock, P., Friend, P., Gotoh, M., Cooper, D. K. C., Park, C. G., O'Connell, P. J., Stabler, C., Matsumoto, S. & 14 others, Ludwig, B., Choudhary, P., Khovatchev, B., Rickels, M. R., Sykes, M., Wood, K., Kraemer, K., Hwa, A., Stanley, E., Ricordi, C., Zimmerman, M., Greenstein, J., Montanya, E. & Otonkoski, T., Jun 21 2016, In : Transplantation. 100, 7, p. e25-e31

Research output: Contribution to journalArticle

16 Scopus citations

Fully automated islet cell counter (ICC) for the assessment of islet mass, purity, and size distribution by digital image analysis

Buchwald, P., Bernal, A., Echeverri, F., Tamayo-Garcia, A., Linetsky, E. & Ricordi, C., 2016, In : Cell Transplantation. 25, 10, p. 1747-1761 15 p.

Research output: Contribution to journalArticle

6 Scopus citations

G-CSF and Exenatide Might Be Associated with Increased Long-Term Survival of Allogeneic Pancreatic Islet Grafts

Zoso, A., Serafini, P., Lanzoni, G., Peixoto, E., Messinger, S., Mantero, A., Padilla-Téllez, N. D., Baidal, D., Alejandro, R., Ricordi, C. & Inverardi, L. A., 2016, In : PLoS One. 11, 6, p. e0157245

Research output: Contribution to journalArticle

3 Scopus citations

Mesenchymal stem cells in Lipogems, a reverse story: From clinical practice to basic science

Tremolada, C., Ricordi, C., Caplan, A. I. & Ventura, C., 2016, Methods in Molecular Biology. Humana Press Inc., Vol. 1416. p. 109-122 14 p. (Methods in Molecular Biology; vol. 1416).

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations

Metformin restrains pancreatic duodenal homeobox-1 (PDX-1) function by inhibiting ERK signaling in pancreatic ductal adenocarcinoma

Zhou, G., Yu, J., Wang, A., Liu, S. H., Sinnett-Smith, J., Wu, J., Sanchez, R., Nemunaitis, J., Ricordi, C., Rozengurt, E. & Brunicardi, F. C., Jan 1 2016, In : Current Molecular Medicine. 16, 1, p. 83-90 8 p.

Research output: Contribution to journalArticle

8 Scopus citations